Strategies for enhancing intratumoral spread of oncolytic adenoviruses
Publication date: Available online 30 May 2020Source: Pharmacology & TherapeuticsAuthor(s): Nasser Hashemi Goradel, Babak Negahdari, Sajjad Ghorghanlu, Samira Jahangiri, Arash Arashkia (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - May 31, 2020 Category: Drugs & Pharmacology Source Type: research

Lipid lowering therapy in cardiovascular disease: From myth to molecular reality
Publication date: Available online 31 May 2020Source: Pharmacology & TherapeuticsAuthor(s): Philipp Mourikis, Saif Zako, Lisa Dannenberg, Amir M. Nia, Yvonne Heinen, Lucas Busch, Hannah Richter, Thomas Hohlfeld, Tobias Zeus, Malte Kelm, Amin Polzin (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - May 31, 2020 Category: Drugs & Pharmacology Source Type: research

FGFR4: A promising therapeutic target for breast cancer and other solid tumors
Publication date: Available online 31 May 2020Source: Pharmacology & TherapeuticsAuthor(s): Kevin M. Levine, Kai Ding, Lyuqin Chen, Steffi Oesterreich (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - May 31, 2020 Category: Drugs & Pharmacology Source Type: research

Induction of programmed necrosis: A novel anti-cancer strategy for natural compounds
Publication date: Available online 31 May 2020Source: Pharmacology & TherapeuticsAuthor(s): Jie Yu, Bingling Zhong, Qingwen Xiao, Lida Du, Ying Hou, Hong-Shuo Sun, Jin-Jian Lu, Xiuping Chen (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - May 31, 2020 Category: Drugs & Pharmacology Source Type: research

Long noncoding RNA loss in immune suppression in cancer
Publication date: Available online 29 May 2020Source: Pharmacology & TherapeuticsAuthor(s): Qingsong Hu, Sergey D. Egranov, Chunru Lin, Liuqing Yang (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - May 30, 2020 Category: Drugs & Pharmacology Source Type: research

New perspectives on the role of Drp1 isoforms in regulating mitochondrial pathophysiology
Publication date: Available online 29 May 2020Source: Pharmacology & TherapeuticsAuthor(s): Ayeshah A. Rosdah, William J. Smiles, Jonathan S. Oakhill, John W. Scott, Christopher G. Langendorf, Lea M.D. Delbridge, Jessica K. Holien, Shiang Y. Lim (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - May 30, 2020 Category: Drugs & Pharmacology Source Type: research

Impact of metformin on immunological markers: Implication in its anti-tumor mechanism
Publication date: Available online 29 May 2020Source: Pharmacology & TherapeuticsAuthor(s): George G. Chen, Peter Y.M. Woo, Stephanie C.P. Ng, George K.C. Wong, Danny T.M. Chan, Charles A. van Hasselt, Michael C.F. Tong, Wai Sang Poon (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - May 30, 2020 Category: Drugs & Pharmacology Source Type: research

Dopamine D2 autoreceptor interactome: Targeting the receptor complex as a strategy for treatment of substance use disorder
Publication date: Available online 27 May 2020Source: Pharmacology & TherapeuticsAuthor(s): Rong Chen, Mark Ferris, Shiyu Wang (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - May 28, 2020 Category: Drugs & Pharmacology Source Type: research

Important lessons learned from studies on the pharmacology of glucocorticoids in human airway smooth muscle cells: Too much of a good thing may be a problem
Publication date: Available online 27 May 2020Source: Pharmacology & TherapeuticsAuthor(s): Yassine Amrani, Reynold A. Panettieri, Patricia Ramos-Ramírez, Dedmer Schaafsma, Klaudia Kaczmarek, Omar Tliba (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - May 28, 2020 Category: Drugs & Pharmacology Source Type: research

Cathepsin L-selective inhibitors: A potentially promising treatment for COVID-19 patients
Publication date: Available online 26 May 2020Source: Pharmacology & TherapeuticsAuthor(s): Tianxiao Liu, Songyuan Luo, Peter Libby, Guo-Ping Shi (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - May 28, 2020 Category: Drugs & Pharmacology Source Type: research

Chemokines in chronic pain: cellular and molecular mechanisms and therapeutic potential
Publication date: Available online 22 May 2020Source: Pharmacology & TherapeuticsAuthor(s): Bao-Chun Jiang, Tong Liu, Yong-Jing Gao (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - May 23, 2020 Category: Drugs & Pharmacology Source Type: research

VMAT2 inhibitors for the treatment of hyperkinetic movement disorders
Publication date: Available online 23 May 2020Source: Pharmacology & TherapeuticsAuthor(s): Jessa Koch, Wei-Xing Shi, Khashayar Dashtipour (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - May 23, 2020 Category: Drugs & Pharmacology Source Type: research

Fine-tuning bispecific therapeutics
Publication date: Available online 23 May 2020Source: Pharmacology & TherapeuticsAuthor(s): Sung In Lim (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - May 23, 2020 Category: Drugs & Pharmacology Source Type: research

PARP inhibition in the ovarian cancer patient: Current approvals and future directions
Publication date: Available online 23 May 2020Source: Pharmacology & TherapeuticsAuthor(s): Katherine C. Kurnit, Monica Avila, Emily Hinchcliff, Robert L. Coleman, Shannon N. Westin (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - May 23, 2020 Category: Drugs & Pharmacology Source Type: research

Targeting the human microbiome and its metabolite TMAO in cardiovascular prevention and therapy
Publication date: Available online 22 May 2020Source: Pharmacology & TherapeuticsAuthor(s): Lisa Dannenberg, Dorothee Zikeli, Marcel Benkhoff, Samantha Ahlbrecht, Malte Kelm, Bodo Levkau, Amin Polzin (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - May 22, 2020 Category: Drugs & Pharmacology Source Type: research