Translating biased agonists from molecules to medications: Serotonin 5-HT1A receptor functional selectivity for CNS disorders
Publication date: Available online 24 June 2021Source: Pharmacology & TherapeuticsAuthor(s): Adrian Newman-Tancredi, Ronan Y. Depoortère, Mark S. Kleven, Marcin Kolaczkowski, Luc Zimmer (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - June 25, 2021 Category: Drugs & Pharmacology Source Type: research
Stepping forward in antibody-drug conjugate development
Publication date: Available online 24 June 2021Source: Pharmacology & TherapeuticsAuthor(s): Yiming Jin, Megan A. Schladetsch, Xueting Huang, Marcy J. Balunas, Andrew J. Wiemer (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - June 25, 2021 Category: Drugs & Pharmacology Source Type: research
Drug repurposing for COVID-19: Approaches, challenges and promising candidates
Publication date: Available online 23 June 2021Source: Pharmacology & TherapeuticsAuthor(s): Yan Ling Ng, Cyrill Kafi Salim, Justin Jang Hann Chu (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - June 24, 2021 Category: Drugs & Pharmacology Source Type: research
TLR4 biased small molecule modulators
Publication date: Available online 23 June 2021Source: Pharmacology & TherapeuticsAuthor(s): Cong Lin, Hongshuang Wang, Miyuan Zhang, Sanam Mustafa, Yibo Wang, Hongyuan Li, Hang Yin, Mark R. Hutchinson, Xiaohui Wang (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - June 24, 2021 Category: Drugs & Pharmacology Source Type: research
Genotoxic therapy and resistance mechanism in gliomas
Publication date: Available online 23 June 2021Source: Pharmacology & TherapeuticsAuthor(s): Fengchao Lang, Yang Liu, Fu-Ju Chou, Chunzhang Yang (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - June 24, 2021 Category: Drugs & Pharmacology Source Type: research
The role of osteoprotegerin (OPG) in fibrosis: Its potential as a biomarker and/or biological target for the treatment of fibrotic diseases
Publication date: Available online 23 June 2021Source: Pharmacology & TherapeuticsAuthor(s): Habibie Habibie, Adhyatmika Adhyatmika, Dedmer Schaafsma, Barbro N. Melgert (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - June 24, 2021 Category: Drugs & Pharmacology Source Type: research
Evidence-based pharmacological treatment options for ADHD in children and adolescents
Publication date: Available online 23 June 2021Source: Pharmacology & TherapeuticsAuthor(s): Konstantin Mechler, Tobias Banaschewski, Sarah Hohmann, Alexander Häge (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - June 24, 2021 Category: Drugs & Pharmacology Source Type: research
Obesity-induced changes in human islet G protein-coupled receptor expression: Implications for metabolic regulation
Publication date: Available online 23 June 2021Source: Pharmacology & TherapeuticsAuthor(s): Patricio Atanes, Tanyel Ashik, Shanta J. Persaud (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - June 24, 2021 Category: Drugs & Pharmacology Source Type: research
Secukinumab for the treatment of psoriasis, psoriatic arthritis, and axial spondyloarthritis: Physical and pharmacological properties underlie the observed clinical efficacy and safety
Publication date: Available online 23 June 2021Source: Pharmacology & TherapeuticsAuthor(s): Frank Kolbinger, Franco Di Padova, Atul Deodhar, Jason E. Hawkes, Christine Huppertz, Torsten Kuiper, Iain B. McInnes, Christopher T. Ritchlin, David Rosmarin, Georg Schett, José M. Carballido, Peter Häusermann, Claudio Calonder, Beate Vogel, Jean-Michel Rondeau, Gerard Bruin (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - June 24, 2021 Category: Drugs & Pharmacology Source Type: research
A review of pre-clinical models for Gulf War Illness
Publication date: Available online 22 June 2021Source: Pharmacology & TherapeuticsAuthor(s): Ana C.R. Ribeiro, Laxmikant S. Deshpande (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - June 23, 2021 Category: Drugs & Pharmacology Source Type: research
Sleep apnea and pulmonary hypertension: A riddle waiting to be solved
Publication date: Available online 22 June 2021Source: Pharmacology & TherapeuticsAuthor(s): Sunil Sharma, Robert Stansbury, Benjamin Hackett, Henrik Fox (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - June 23, 2021 Category: Drugs & Pharmacology Source Type: research
The mechanism of action of N-acetylcysteine (NAC): The emerging role of H2S and sulfane sulfur species
Publication date: Available online 23 June 2021Source: Pharmacology & TherapeuticsAuthor(s): Brandán Pedre, Uladzimir Barayeu, Daria Ezeriņa, Tobias P. Dick (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - June 23, 2021 Category: Drugs & Pharmacology Source Type: research
Animal models of SARS-CoV-2 and COVID-19 for the development of prophylactic and therapeutic interventions
Publication date: Available online 23 June 2021Source: Pharmacology & TherapeuticsAuthor(s): Marcel Renn, Eva Bartok, Thomas Zillinger, Gunther Hartmann, Rayk Behrendt (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - June 23, 2021 Category: Drugs & Pharmacology Source Type: research
Efferocytosis of vascular cells in cardiovascular disease
Publication date: Available online 23 June 2021Source: Pharmacology & TherapeuticsAuthor(s): Jody Tori O. Cabrera, Ayako Makino (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - June 23, 2021 Category: Drugs & Pharmacology Source Type: research
The gabapentinoid drugs and their abuse potential
Publication date: Available online 22 June 2021Source: Pharmacology & TherapeuticsAuthor(s): Aleyah Goins, Keisha Patel, Sascha R.A. Alles (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - June 22, 2021 Category: Drugs & Pharmacology Source Type: research
