Functional metabolomics innovates therapeutic discovery of traditional Chinese medicine derived functional compounds
Publication date: Available online 2 March 2021Source: Pharmacology & TherapeuticsAuthor(s): Tianyu Wang, Jingjing Liu, Xialin Luo, Longlong Hu, Haitao Lu (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - March 3, 2021 Category: Drugs & Pharmacology Source Type: research

Inter and intra-tumoral heterogeneity as a platform for personalized therapies in medulloblastoma
Publication date: Available online 1 March 2021Source: Pharmacology & TherapeuticsAuthor(s): Marina Danilenko, Steven C. Clifford, Edward C. Schwalbe (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - March 3, 2021 Category: Drugs & Pharmacology Source Type: research

Benzamide derivative radiotracers targeting melanin for melanoma imaging and therapy: Preclinical/clinical development and combination with other treatments
Publication date: Available online 1 March 2021Source: Pharmacology & TherapeuticsAuthor(s): Jacques Rouanet, Mercedes Quintana, Philippe Auzeloux, Florent Cachin, Françoise Degoul (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - March 3, 2021 Category: Drugs & Pharmacology Source Type: research

SARS-CoV-2 and other coronaviruses negatively influence mitochondrial quality control: beneficial effects of melatonin
Publication date: Available online 1 March 2021Source: Pharmacology & TherapeuticsAuthor(s): Saeed Mehrzadi, Mohammad Yahya Karimi, Alireza Fatemi, Russel J. Reiter, Azam Hosseinzadeh (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - March 3, 2021 Category: Drugs & Pharmacology Source Type: research

Cyclic nucleotide phosphodiesterase inhibitors as therapeutic interventions for cystic fibrosis
Publication date: Available online 1 March 2021Source: Pharmacology & TherapeuticsAuthor(s): Mark J. Turner, Kathy Abbott-Banner, David Y. Thomas, John W. Hanrahan (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - March 3, 2021 Category: Drugs & Pharmacology Source Type: research

Endothelial function and dysfunction: Impact of sodium-glucose cotransporter 2 inhibitors
Publication date: Available online 1 March 2021Source: Pharmacology & TherapeuticsAuthor(s): Azizah Ugusman, Jaya Kumar, Amilia Aminuddin (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - March 3, 2021 Category: Drugs & Pharmacology Source Type: research

Metabolomics, metabolic flux analysis and cancer pharmacology
Publication date: Available online 1 March 2021Source: Pharmacology & TherapeuticsAuthor(s): Lingfan Liang, Fei Sun, Hongbo Wang, Zeping Hu (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - March 3, 2021 Category: Drugs & Pharmacology Source Type: research

TAS-102: A resurrected novel Fluoropyrimidine with expanding role in the treatment of gastrointestinal malignancies
Publication date: Available online 2 March 2021Source: Pharmacology & TherapeuticsAuthor(s): Sakti Chakrabarti, Grant Wintheiser, Sri Harsha Tella, Carolyn Oxencis, Amit Mahipal (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - March 3, 2021 Category: Drugs & Pharmacology Source Type: research

Advances in the pathophysiology of atopic dermatitis revealed by novel therapeutics and clinical trials
Publication date: Available online 2 March 2021Source: Pharmacology & TherapeuticsAuthor(s): Xiaoliang Yang, Naotomo Kambe, Riko Takimoto-Ito, Kenji Kabashima (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - March 3, 2021 Category: Drugs & Pharmacology Source Type: research

Exploring the “other” subfamily of HECT E3-ligases for therapeutic intervention
Publication date: Available online 16 February 2021Source: Pharmacology & TherapeuticsAuthor(s): Sunil Singh, Joel Ng, J. Sivaraman (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - February 17, 2021 Category: Drugs & Pharmacology Source Type: research

Purinergic transmission in depressive disorders
Publication date: Available online 17 February 2021Source: Pharmacology & TherapeuticsAuthor(s): Aleksandra Szopa, Katarzyna Socała, Anna Serefko, Urszula Doboszewska, Andrzej Wróbel, Ewa Poleszak, Piotr Wlaź (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - February 17, 2021 Category: Drugs & Pharmacology Source Type: research

RGS proteins, GRKs, and beta-arrestins modulate G protein-mediated signaling pathways in asthma
Publication date: Available online 15 February 2021Source: Pharmacology & TherapeuticsAuthor(s): Nathalie Fuentes, Morgan McCullough, Reynold A. Panettieri, Kirk M. Druey (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - February 16, 2021 Category: Drugs & Pharmacology Source Type: research

Nitrite and myocardial ischaemia reperfusion injury. Where are we now?
Publication date: Available online 15 February 2021Source: Pharmacology & TherapeuticsAuthor(s): Kayleigh Griffiths, Jordan J. Lee, Michael P. Frenneaux, Martin Feelisch, Melanie Madhani (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - February 16, 2021 Category: Drugs & Pharmacology Source Type: research

Oxytocin signaling in the treatment of drug addiction: Therapeutic opportunities and challenges
Publication date: Available online 15 February 2021Source: Pharmacology & TherapeuticsAuthor(s): Xiaohang Che, Jialing Cai, Yueyang Liu, Tianyu Xu, Jingyu Yang, Chunfu Wu (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - February 16, 2021 Category: Drugs & Pharmacology Source Type: research

Cellular senescence and hematological malignancies: From pathogenesis to therapeutics
Publication date: Available online 12 February 2021Source: Pharmacology & TherapeuticsAuthor(s): Dingyu Hu, Shunling Yuan, Jing Zhong, Zhaoping Liu, Yanyan Wang, Li Liu, Junjun Li, Feng Wen, Jing Liu, Ji Zhang (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - February 14, 2021 Category: Drugs & Pharmacology Source Type: research