Extracorporeal membrane oxygenation as a bridge to decision or recovery: Medical and ethical dilemmas
Publication date: July 2013 Source:Personalized Medicine Universe, Volume 2 Author(s): Shigeki Tabata , James T. Diehl , Nicholas C. Cavarocchi , Hitoshi Hirose Extracorporeal life support has advanced from its humble beginnings over 3 decades ago, with the first description of its success in a patient with Acute Respiratory Distress Syndrome (ARDS), going as far back as 1971. The indications for extracorporeal membrane oxygenation (ECMO) therapy include refractory respiratory and/or cardiac failure, and ECMO is now being increasingly used in adult patients. In this case report, we present a patient who had travele...
Source: Personalized Medicine Universe - November 6, 2014 Category: Drugs & Pharmacology Source Type: research
High dose IV vitamin C for treatment of prostate adenocarcinoma
We report here a case study of a patient who has diagnosed prostate cancer of Gleason's pattern 7. We found that, at the end of ten months of treatment with high dose IV vitamin C, the vascular tumor that was present before on the left mid-gland area of the prostate was no longer detectable on the ultrasound. In the light of the recent evidence showing anti-tumor activity of vitamin C, the role of high dose IV vitamin C for cancer should be considered further. (Source: Personalized Medicine Universe)
Source: Personalized Medicine Universe - November 6, 2014 Category: Drugs & Pharmacology Source Type: research
Mineral fasting based on ortho-molecular medicine for healthy weight control
Publication date: July 2013 Source:Personalized Medicine Universe, Volume 2 Author(s): Minoru Arakaki , Li Li , Toyofumi Yamada In slimming therapy in plastic and cosmetic surgery, treatment based on internal medicine rather than surgical treatments is a viable option. Such surgical treatments, which include liposuction and plastic surgery of the abdominal wall, are contour plasty or partial-slimming techniques, and are not intended for the purpose of weight loss. For reduction of body weight and visceral fat as well as relief from lifestyle-related diseases, this article describes the application of ortho-molecular...
Source: Personalized Medicine Universe - November 6, 2014 Category: Drugs & Pharmacology Source Type: research
A Coleus forskohlii extract improves body composition in healthy volunteers: An open-label trial
Conclusion These findings suggest that CF root extract has potential as an adjunct therapy for the treatment of obesity. Further studies using double-blind, randomized, placebo-controlled designs are warranted to conclusively demonstrate the effectiveness of CF root extract in personalized supplements and/or pharmacological interventions. (Source: Personalized Medicine Universe)
Source: Personalized Medicine Universe - November 6, 2014 Category: Drugs & Pharmacology Source Type: research
Detection of aberrant methylation of tumor suppressor genes in plasma from cancer patients
Conclusion Our results indicate that the frequency of methylation of cancer-related genes is dependent on the type of cancer and patient. Therefore, DNA methylation of cancer-related genes has a high potential as a biomarker for personalized medicine. (Source: Personalized Medicine Universe)
Source: Personalized Medicine Universe - November 6, 2014 Category: Drugs & Pharmacology Source Type: research
DL–/PO–phosphatidylcholine serves as a memory enhancer for normal healthy subjects
Conclusion The results of the present study indicate that DL–/PO–PC could enhance long-term memory potential for normal healthy subjects. (Source: Personalized Medicine Universe)
Source: Personalized Medicine Universe - November 6, 2014 Category: Drugs & Pharmacology Source Type: research
DL-/PO-phosphatidylcholine may shed light on the treatment of Alzheimer dementia
Conclusion The results of the present study demonstrate that DL-/PO-PC could be an effective therapeutic agent for Alzheimer dementia. (Source: Personalized Medicine Universe)
Source: Personalized Medicine Universe - November 6, 2014 Category: Drugs & Pharmacology Source Type: research
Use of diagnostic and therapeutic biomarkers in personalized oncology based on adult T-cell leukemia/lymphoma research
Publication date: July 2013 Source:Personalized Medicine Universe, Volume 2 Author(s): Hiroo Hasegawa , Shimeru Kamihira Human T-lymphotropic virus type 1 (HTLV-1) infection is linked to a spectrum of diverse diseases, including adult T-cell leukemia/lymphoma (ATLL) and the chronic neuromyelopathy tropical spastic paraparesis or HTLV-1 associated myelopathy (TSP/HAM). ATLL is a neoplasm of mature CD4+ T-cell origin known to be resistant to standard anti-cancer therapies. Based on ATLL research performed in our laboratory as well as other reports, we discuss diagnostic, predictive, and pharmacological biomarkers for c...
Source: Personalized Medicine Universe - November 6, 2014 Category: Drugs & Pharmacology Source Type: research
Current status of myocardial regeneration therapy
Publication date: July 2013 Source:Personalized Medicine Universe, Volume 2 Author(s): Yoshiki Sawa Myocardial regeneration therapy has emerged as an alternative therapy for heart failure and is expected to replace the current conventional therapies. Resident cardiac stem cells have been detected and reported as a cell source by many researchers. These resident cardiac stem cells show multipotency and are considered to differentiate into myocytes. Meanwhile, bone marrow stem cells have received the greatest attention as a cell source for cell transplantation therapy in the current era, with a larger number of clinical...
Source: Personalized Medicine Universe - November 6, 2014 Category: Drugs & Pharmacology Source Type: research
Expectations for innovation of personalized medicine
Publication date: July 2013 Source:Personalized Medicine Universe, Volume 2 Author(s): Hiroyuki Abe (Source: Personalized Medicine Universe)
Source: Personalized Medicine Universe - November 6, 2014 Category: Drugs & Pharmacology Source Type: research
Comments on the business of genetic testing
Publication date: July 2014 Source:Personalized Medicine Universe, Volume 3 Author(s): Hirohiko Matsumoto (Source: Personalized Medicine Universe)
Source: Personalized Medicine Universe - November 6, 2014 Category: Drugs & Pharmacology Source Type: research
Role of mitochondrial DNA changes in prostate cancer progression
Publication date: July 2014 Source:Personalized Medicine Universe, Volume 3 Author(s): Masahiro Higuchi , Ara Kim , Cody C. Cook , Sara Prior , Akinobu Gotoh (Source: Personalized Medicine Universe)
Source: Personalized Medicine Universe - November 6, 2014 Category: Drugs & Pharmacology Source Type: research
Serum concentrations of diterpenoid alkaloids after oral administration of powdered processed aconite root
Publication date: July 2014 Source:Personalized Medicine Universe, Volume 3 Author(s): Hajime Nakae , Yuji Fujita , Shigeatsu Endo (Source: Personalized Medicine Universe)
Source: Personalized Medicine Universe - November 6, 2014 Category: Drugs & Pharmacology Source Type: research
Improvement of refractory schizophrenia on using Amyloban®3399 extracted from Hericium erinaceum
Publication date: July 2014 Source:Personalized Medicine Universe, Volume 3 Author(s): Kazutoyo Inanaga , Taketoshi Matsuki , Yoshio Hoaki , Koji Miki , Akira Shigemoto , Susumu Hirota , Nobuhiro Mori , Nobuyuki Hattori (Source: Personalized Medicine Universe)
Source: Personalized Medicine Universe - November 6, 2014 Category: Drugs & Pharmacology Source Type: research
Marked improvement of neurocognitive impairment after treatment with compounds from Hericium erinaceum: A case study of recurrent depressive disorder
Publication date: July 2014 Source:Personalized Medicine Universe, Volume 3 Author(s): Kazutoyo Inanaga (Source: Personalized Medicine Universe)
Source: Personalized Medicine Universe - November 6, 2014 Category: Drugs & Pharmacology Source Type: research
