The effects of Hericium erinaceus (Amyloban ® 3399) on sleep quality and subjective well-being among female undergraduate students: A pilot study
Publication date: July 2015 Source:Personalized Medicine Universe, Volume 4 Author(s): Hisayoshi Okamura, Nobuko Anno, Akira Tsuda, Takahiro Inokuchi, Naohisa Uchimura, Kazutoyo Inanaga (Source: Personalized Medicine Universe)
Source: Personalized Medicine Universe - July 20, 2016 Category: Drugs & Pharmacology Source Type: research

Protein factors and chemical compounds regulating hypoxic or  oxidative stress responses
Conclusions Hypoxic and oxidative stress responses are regulated by common factors and are closely linked to each other. (Source: Personalized Medicine Universe)
Source: Personalized Medicine Universe - July 20, 2016 Category: Drugs & Pharmacology Source Type: research

An attempt to design optimal personalized exercise prescriptions using the KEIO-SENIOR treadmill protocol for patients with type 2 diabetes
In conclusion, our results suggest that this protocol, the main purpose of which was not to detect coronary ischemia, was a useful tool to evaluate physical fitness and to prescribe exercises for middle-aged or elderly Japanese patients. (Source: Personalized Medicine Universe)
Source: Personalized Medicine Universe - July 2, 2016 Category: Drugs & Pharmacology Source Type: research

Evolution of autologous endothelial progenitor cell therapy for tissue regeneration and vasculogenesis
Publication date: Available online 14 June 2016 Source:Personalized Medicine Universe Author(s): Hiroko Hagiwara, Rica Tanaka Endothelial progenitor cell (EPC) transplantation therapy is a promising method in the field of regenerative therapy. EPCs, which were identified in adult peripheral blood, have the ability to differentiate into endothelial cells (ECs). Because of the potential for EPCs to promote tissue regeneration, transplantation of autologous EPCs is now recognized as a novel therapeutic option for revascularization and blood vessel repair in ischemic diseases, diabetic refractory limb ulcers, and other...
Source: Personalized Medicine Universe - June 13, 2016 Category: Drugs & Pharmacology Source Type: research

Discussion of current ethical issues regarding the use of assisted reproductive treatment in Japan
Conclusions In modern Japan, legislation on ART urgently needs to be prepared. Such laws must sufficiently take into consideration the human rights of the next generation. The welfare of the child should be afforded the utmost respect. (Source: Personalized Medicine Universe)
Source: Personalized Medicine Universe - June 1, 2016 Category: Drugs & Pharmacology Source Type: research

Perspectives on targeting the phosphatidylinositol 3-kinase pathway for personalized medicine in endometrial and ovarian cancers
Publication date: Available online 11 May 2016 Source:Personalized Medicine Universe Author(s): Katsutoshi Oda, Yuji Ikeda, Tomoko Kashiyama, Aki Miyasaka, Kanako Inaba, Yuichiro Miyamoto, Osamu Wada-Hiraike, Kei Kawana, Yutaka Osuga, Tomoyuki Fujii Endometrial and ovarian cancers show similar genetic and pathological backgrounds. In particular, high frequencies of activating mutations in the phosphatidylinositol 3-kinase (PI3K) pathway, including mutations in PIK3CA and PTEN, are found in both estrogen-dependent endometrial cancer (type I endometrioid carcinomas) and ovarian clear cell and endometr...
Source: Personalized Medicine Universe - May 10, 2016 Category: Drugs & Pharmacology Source Type: research

New era in personalized medicine
Publication date: Available online 6 May 2016 Source:Personalized Medicine Universe Author(s): Hiroyuki Abe (Source: Personalized Medicine Universe)
Source: Personalized Medicine Universe - May 6, 2016 Category: Drugs & Pharmacology Source Type: research

An evidence-based review: Anti-obesity effects of Coleus forskohlii
Conclusion The C. forskohlii extract showed a substantial effect on weight loss and was safe and effective in reducing body fat in overweight/obese people. However, additional trials with high quality are required to establish a high level of evidence for the appropriate use of C. forskohlii extract as a personalized supplement and/or a pharmacological intervention. (Source: Personalized Medicine Universe)
Source: Personalized Medicine Universe - April 1, 2016 Category: Drugs & Pharmacology Source Type: research

Computed tomography-guided balloon-assisted endovascular recanalization and angioplasty in Leriche syndrome
We present a report of a novel angioplasty technique for Leriche syndrome; we performed computed tomography (CT)-guided balloon-assisted recanalization after failure of a conventional recanalization technique. A 58-year-old man with occlusion of the infrarenal abdominal aorta was treated using endovascular stenting after failure to cross the occlusion using a guidewire. With a balloon catheter placed at the distal end of the abdominal aorta, the opposite end of the guidewire was advanced from the proximal side of the aortic occlusion under CT guidance, following which stents were placed in left and right iliac arteries and...
Source: Personalized Medicine Universe - March 12, 2016 Category: Drugs & Pharmacology Source Type: research

On the neuronal connectivity of our thoughts into actions
Publication date: Available online 27 February 2016 Source:Personalized Medicine Universe Author(s): Jack Kushner (Source: Personalized Medicine Universe)
Source: Personalized Medicine Universe - February 29, 2016 Category: Drugs & Pharmacology Source Type: research

Improvised prophecy using regularization method of machine learning algorithms on medical data
Publication date: Available online 21 October 2015 Source:Personalized Medicine Universe Author(s): Vadamodula Prasad, T. Srinivasa Rao, P.V.G.D. Prasad Reddy Patients with thyroid disease (TD) boast continuously increasing because of excessive growth of thyroid gland and its hormones. Automatic classification tools may reduce the burden on doctors. This paper evaluates the selected algorithms for predicting thyroid disease diagnoses (TDD). The algorithms considered here are regularization methods (RM) of machine learning algorithms (MLA). The analysis report generated by the proposed work suggests the best algor...
Source: Personalized Medicine Universe - October 23, 2015 Category: Drugs & Pharmacology Source Type: research

Corrigendum to “DL-/PO-phosphatidylcholine serves as a memory enhancer for normal healthy subjects” [Pers Med Univ 2 (2013) 16–19]
Publication date: Available online 18 July 2015 Source:Personalized Medicine Universe Author(s): Takaaki Nishimoto, Takeshi Kanno, Akinobu Gotoh, Tomoyuki Nishizaki (Source: Personalized Medicine Universe)
Source: Personalized Medicine Universe - July 19, 2015 Category: Drugs & Pharmacology Source Type: research

A novel therapeutic strategy for mycoplasma infectious diseases
Publication date: Available online 9 May 2015 Source:Personalized Medicine Universe Author(s): Kazuhiro Matsuda Mycoplasma Infectious Diseases (MID) are systemic illnesses that cause vasculitis and neuritis. MID not only includes pneumonia but also diseases such as asthma, arthritis, nephritis, meningitis, encephalitis, dermatitis, pancreatitis, hepatitis, and hematologic illnesses. The broader concept of MID encompasses acute to chronic phases with diverse symptoms. Therefore, it is often confusing and difficult to identify Mycoplasma-infected patients among those with incurable diseases, such as autoimmune diseases,...
Source: Personalized Medicine Universe - May 9, 2015 Category: Drugs & Pharmacology Source Type: research

Protein factors and chemical compounds regulating hypoxic or oxidative stress responses
Conclusions Hypoxic and oxidative stress responses are regulated by common factors and are closely linked to each other. (Source: Personalized Medicine Universe)
Source: Personalized Medicine Universe - May 9, 2015 Category: Drugs & Pharmacology Source Type: research

The effects of Hericium erinaceus (Amyloban® 3399) on sleep quality and subjective well-being among female undergraduate students: A pilot study
Publication date: Available online 9 May 2015 Source:Personalized Medicine Universe Author(s): Hisayoshi Okamura , Nobuko Anno , Akira Tsuda , Takahiro Inokuchi , Naohisa Uchimura , Kazutoyo Inanaga (Source: Personalized Medicine Universe)
Source: Personalized Medicine Universe - May 9, 2015 Category: Drugs & Pharmacology Source Type: research