Current state and issues related to cell therapy under the Act on the Safety of Regenerative Medicine
Publication date: July 2018Source: Personalized Medicine Universe, Volume 7Author(s): Morikuni TobitaAbstractIn May the 2013, Regenerative Medicine Promotion Act was enacted in order to promote regenerative medicine in Japan. Based on this Act, in November 2014, the Act on the Safety of Regenerative Medicine, which ensured the safety of regenerative medicine, was put into effect. The Act on the Safety of Regenerative Medicine was intended to promote the swift and safe provision and promulgation of regenerative medicine, and it applies to both clinical research and private practice that utilizes regenerative medicine.In thi...
Source: Personalized Medicine Universe - July 6, 2018 Category: Drugs & Pharmacology Source Type: research
Novel biologic products and Post-Bio strategy
Publication date: July 2018Source: Personalized Medicine Universe, Volume 7Author(s): Kusuki Nishioka (Source: Personalized Medicine Universe)
Source: Personalized Medicine Universe - July 6, 2018 Category: Drugs & Pharmacology Source Type: research
Novel biologic products and Post-Bio strategy
Publication date: Available online 12 April 2018 Source:Personalized Medicine Universe Author(s): Kusuki Nishioka (Source: Personalized Medicine Universe)
Source: Personalized Medicine Universe - April 13, 2018 Category: Drugs & Pharmacology Source Type: research
Clinical study of the efficacy of a yeast containing S-adenosyl methionine on knee osteoarthritis
Publication date: July 2017 Source:Personalized Medicine Universe, Volume 6 Author(s): Yukio Mitsui, Maki Satou, Shinichi Shimizu, Hiroshi Mitsui, Hirohiko Matsumoto (Source: Personalized Medicine Universe)
Source: Personalized Medicine Universe - July 11, 2017 Category: Drugs & Pharmacology Source Type: research
Diagnosis and treatment in the era of precision medicine – Precision medicine and tailor-made medicine
Publication date: Available online 23 June 2017 Source:Personalized Medicine Universe Author(s): Masayoshi Nagata, Shigeo Horie Recently, precision medicine has gained attention in several fields of medical society. Today's medical consensus revolves around Evidence-Based Medicine (EBM) built on the results of many randomized controlled trials. Ever since the advent of EBM, guidelines based on EBM have provided a basis for clinical decision-making. Treatments based on these guidelines largely improved the prognosis of a certain ailment. However, these guidelines can only provide the best fit based on the statistics. Tr...
Source: Personalized Medicine Universe - June 24, 2017 Category: Drugs & Pharmacology Source Type: research
Detection of aberrant DNA methylation of tumor suppressor genes in circulating tumor cells from a pancreatic cancer patient
Publication date: Available online 2 June 2017 Source:Personalized Medicine Universe Author(s): Hiroaki Kawasaki, Hiroyuki Abe (Source: Personalized Medicine Universe)
Source: Personalized Medicine Universe - June 2, 2017 Category: Drugs & Pharmacology Source Type: research
A case of advanced ovarian cancer effectively treated with a combination of multi-peptide dendritic cell immunotherapy, surgery, and chemotherapy
Publication date: Available online 2 June 2017 Source:Personalized Medicine Universe Author(s): Amane Sasada, Minako Abe, Hiroyuki Abe (Source: Personalized Medicine Universe)
Source: Personalized Medicine Universe - June 2, 2017 Category: Drugs & Pharmacology Source Type: research
Oral administration of freeze-dried powders of honey bee larvae inhibits the development of atopic dermatitis-like skin lesions in NC/Nga mice
Conclusions Our results indicate that oral administration of the freeze-dried honey bee larvae powder could provide an adjunctive therapy for the management of AD. (Source: Personalized Medicine Universe)
Source: Personalized Medicine Universe - May 29, 2017 Category: Drugs & Pharmacology Source Type: research
Gap in perception regarding recovery between patients and nurses in recovery-stage rehabilitation ward
Publication date: Available online 28 May 2017 Source:Personalized Medicine Universe Author(s): Masumi Kumada, Miki Matsunami (Source: Personalized Medicine Universe)
Source: Personalized Medicine Universe - May 28, 2017 Category: Drugs & Pharmacology Source Type: research
Chlorogenic acid modulates hypoxia response of Hep3B cells
Publication date: Available online 27 May 2017 Source:Personalized Medicine Universe Author(s): Ferbian Milas Siswanto, Ami Oguro, Susumu Imaoka Coffee is the most widely consumed beverage around the world, and it contains many compounds that have beneficial effects on human health. Chlorogenic acid (CGA), the most abundant polyphenol in coffee, has been reported to inhibit cancer cell growth and has a beneficial effect on ameliorating aging-related diseases. We found that CGA decreased HIF-1α levels in human hepatoma cell line Hep3B under hypoxic conditions (O2 = 1%) in a dose-dependent manner, thereby decreasing ...
Source: Personalized Medicine Universe - May 27, 2017 Category: Drugs & Pharmacology Source Type: research
DNA methylation analysis of cancer-related genes from cell-free DNA of patients with cancer
Publication date: Available online 26 May 2017 Source:Personalized Medicine Universe Author(s): Yukie Saeki, Minako Abe, Fumika Kono, Akane Nakazato, Yoshimori Ishihara, Hiroyuki Abe DNA methylation is a very important mechanism for regulating gene expression in normal development and cell differentiation. However, DNA methylation, when acting on the promoter region of a tumor suppressor gene, suppresses transcription and is one of the major epigenetic modifications involved in the development and progression of many cancers (Wajed et al., 2001; Morris and Chan 2015) [1,2]. In our laboratory, we have carried out m...
Source: Personalized Medicine Universe - May 26, 2017 Category: Drugs & Pharmacology Source Type: research
Efficacy and safety of a compound supplement containing glucosamine, chondroitin, and five bioactive ingredients in volunteers with knee joint pain
Conclusion These findings suggest that the compound supplementation of functional food ingredients has potential as an adjunctive and safe therapy for knee OA. (Source: Personalized Medicine Universe)
Source: Personalized Medicine Universe - May 16, 2017 Category: Drugs & Pharmacology Source Type: research
On molecularly personalized medicine clinical trials
Publication date: Available online 2 February 2017 Source:Personalized Medicine Universe Author(s): Reza Sanaye, Babak Daneshfard (Source: Personalized Medicine Universe)
Source: Personalized Medicine Universe - February 1, 2017 Category: Drugs & Pharmacology Source Type: research
DL –/PO–phosphatidylcholine serves as a memory enhancer for normal healthy subjects
Conclusion The results of the present study indicate that DL–/PO–PC could enhance long-term memory potential for normal healthy subjects. (Source: Personalized Medicine Universe)
Source: Personalized Medicine Universe - July 20, 2016 Category: Drugs & Pharmacology Source Type: research
Improvement of refractory schizophrenia on using Amyloban ®3399 extracted from Hericium erinaceum
Publication date: July 2014 Source:Personalized Medicine Universe, Volume 3 Author(s): Kazutoyo Inanaga, Taketoshi Matsuki, Yoshio Hoaki, Koji Miki, Akira Shigemoto, Susumu Hirota, Nobuhiro Mori, Nobuyuki Hattori (Source: Personalized Medicine Universe)
Source: Personalized Medicine Universe - July 20, 2016 Category: Drugs & Pharmacology Source Type: research
