Acyclovir
Publication date: October–December 2013 Source:Pediatric Infectious Disease, Volume 5, Issue 4 Author(s): Parang Mehta Acyclovir is one of the oldest antiviral drugs, having been in use for three decades now. It is an acyclic guanosine derivative and has activity mainly against herpes virus-1 (HSV-1), herpes virus-2 (HSV-2), and varicella zoster virus (VZV). It is only weakly active against Epstein–Barr virus (EBV), cytomegalovirus (CMV), and human herpes virus-6 (HHV-6), and not used for these infections. It acts by inhibition of viral DNA synthesis. Before it can act, it has to be phosphorylated by virus-specifi...
Source: Pediatric Infectious Disease - October 13, 2014 Category: Pediatrics Source Type: research
A case report of acute glomerulonephritis associated with typhoid fever
We present this case of acute glomerulonephritis associated with typhoid fever in a 4-year-old boy who presented with high fever, abdominal symptoms, edema, oliguria, hypertension and hematuria and who recovered completely with treatment. (Source: Pediatric Infectious Disease)
Source: Pediatric Infectious Disease - October 13, 2014 Category: Pediatrics Source Type: research
Acute pancreatitis in hepatitis A infection in a 10-year-old boy
Publication date: October–December 2013 Source:Pediatric Infectious Disease, Volume 5, Issue 4 Author(s): Sudhir Kumar Rana , Ragini Singh , Bindu Aggarwal , Shruti Kumar Association of acute pancreatitis with hepatitis A infection is very low in younger children. Usually pancreatitis occurs in early stage of illness and may present as acute abdomen in a setting of viral hepatitis infection. Clinical features are usually milder than radiological features. We are reporting a case of 10-year-old boy with acute hepatitis A infection who later developed acute pancreatitis in course of illness. He improved with conser...
Source: Pediatric Infectious Disease - October 13, 2014 Category: Pediatrics Source Type: research
Survey of Indian pediatricians: Clinic-prevalence, diagnostic and management strategies for acute otitis media
Conclusions The reported perceived clinic-prevalence of AOM was higher (35%) than anticipated (about 10%) in pediatric practice. More than half of the clinicians surveyed used otoscopy to diagnose AOM, and majority of the respondents who diagnosed AOM otoscopically opted to use an antibiotic at presentation. Amoxicillin/clavulanic acid was the preferred antibiotic for treating acute otitis media. Most pediatricians also used analgesics and decongestants for symptomatic relief. (Source: Pediatric Infectious Disease)
Source: Pediatric Infectious Disease - October 13, 2014 Category: Pediatrics Source Type: research
Neonatal infections: Challenges & opportunities
Publication date: October–December 2013 Source:Pediatric Infectious Disease, Volume 5, Issue 4 Author(s): Rhishikesh Thakre (Source: Pediatric Infectious Disease)
Source: Pediatric Infectious Disease - October 13, 2014 Category: Pediatrics Source Type: research
Neonatal septicemia – Emergence of coagulase negative Staphylococcus as major etiological agent
Publication date: Available online 2 December 2013 Source:Pediatric Infectious Disease Author(s): Sandesh Guleria , Ram Krishan Kaushal , Jyoti Sharma This prospective observational study done at tertiary care hospital was designed to know clinico–etiological profile & sensitivity pattern of neonatal septicemia in this region. Newborns with clinical suspicion of septicemia and positive blood culture were studied. 42.6% cases with suspected sepsis were blood culture positive. Most frequent organism isolated was coagulase negative Staphylococcus (CONS) in 23.5% followed by Staphylococcus aureus 19%, and Kleb...
Source: Pediatric Infectious Disease - October 13, 2014 Category: Pediatrics Source Type: research
Co-existence of lupus vulgaris with lichen scrofulosorum – A rare association
We report two cases of co-existence of lupus vulgaris with lichen scrofulosorum, where any systemic focus of tuberculosis could not be identified, and responded to anti-tubercular therapy. (Source: Pediatric Infectious Disease)
Source: Pediatric Infectious Disease - October 13, 2014 Category: Pediatrics Source Type: research
What's in
Publication date: January–March 2014 Source:Pediatric Infectious Disease, Volume 6, Issue 1 Author(s): Anita Shet (Source: Pediatric Infectious Disease)
Source: Pediatric Infectious Disease - October 13, 2014 Category: Pediatrics Source Type: research
A three-year-old female child with peri-orbital cellulitis
Publication date: January–March 2014 Source:Pediatric Infectious Disease, Volume 6, Issue 1 Author(s): S. Balasubramanian , Sumanth Amperayani , K. Dhanalakshmi , Narayanan (Source: Pediatric Infectious Disease)
Source: Pediatric Infectious Disease - October 13, 2014 Category: Pediatrics Source Type: research
Common laboratory errors
Publication date: January–March 2014 Source:Pediatric Infectious Disease, Volume 6, Issue 1 Author(s): Baldev S. Prajapati , Rajal B. Prajapati , Hetal D. Vora In this modern era of technology, there is plethora of investigations available in the market, but without deriving clinical diagnosis, indiscriminate use of laboratory investigations is expensive & misguiding. Laboratory investigations are neither shortcut nor final answer to the diagnosis. Laboratory investigations should be planned after clinical diagnosis, derived from history & clinical examination. The clinician should also know the se...
Source: Pediatric Infectious Disease - October 13, 2014 Category: Pediatrics Source Type: research
Immunization status of children and the influence of social factors: A hospital based study in western Uttar Pradesh
Conclusions There is need for improving economic and educational status of families for reducing the burden of vaccine preventable diseases. (Source: Pediatric Infectious Disease)
Source: Pediatric Infectious Disease - October 13, 2014 Category: Pediatrics Source Type: research
Evaluation of efficacy and adherence to INH preventive therapy in children at risk to develop active tuberculosis
Conclusions Our study suggests that IPT is effective in preventing active disease in both children in contact with infectious adults and those with nephrotic syndrome and latent infection. Adherence can be enhanced by counseling of parents at the start of therapy and reemphasis during subsequent follow-ups. (Source: Pediatric Infectious Disease)
Source: Pediatric Infectious Disease - October 13, 2014 Category: Pediatrics Source Type: research
Subacute sclerosing panencephalitis after measles vaccination and without clinical measles, vaccine induced or something else: A case report
Publication date: January–March 2014 Source:Pediatric Infectious Disease, Volume 6, Issue 1 Author(s): Nikhil Bansal , Raghvendra Narayan Subacute sclerosing panencephalitis (SSPE) is a progressive neurological disorder characterized by behavioral changes, myoclonus, dementia, visual disturbances, pyramidal and extra pyramidal signs. The disease has a gradual progressive course leading to death within few years of its onset. SSPE in a child who has received measles vaccine and having no clinically apparent measles in the past is a rare occurrence. Although these type of cases have been reported worldwide its pathog...
Source: Pediatric Infectious Disease - October 13, 2014 Category: Pediatrics Source Type: research
Life threatening allergic bronchopulmonary aspergillosis (ABPA) in a previously well child due to acute exposure to pulse infested with Aspergillus flavus
We report a well 14-year-old boy progressing to respiratory failure following exposure to fungal infested grains, causing severe life-threatening bronchospasm. Such an acute severe presentation of ABPA in a previously well child has not been reported before. (Source: Pediatric Infectious Disease)
Source: Pediatric Infectious Disease - October 13, 2014 Category: Pediatrics Source Type: research
Diagnosis and management of malaria in children: Recommendations and IAP plan of action
Publication date: January–March 2014 Source:Pediatric Infectious Disease, Volume 6, Issue 1 Author(s): Ritabrata Kundu The problem of malaria is further exacerbated by development of resistance to first line antimalarial chloroquine (CQ). This is mainly due to presumptive use of CQ with increase drug pressure. Hence every case of suspected malaria needs a parasitological diagnosis. Rapid diagnostic test (RDT) are ready to use test available even in remote parts which does not need any expertise. For management of uncomplicated vivax malaria CQ is still the drug of choice. Whereas, falciparum malaria should be treate...
Source: Pediatric Infectious Disease - October 13, 2014 Category: Pediatrics Source Type: research
