Subacute sclerosing panencephalitis after measles vaccination and without clinical measles, vaccine induced or something else: A case report

Publication date: January–March 2014 Source:Pediatric Infectious Disease, Volume 6, Issue 1 Author(s): Nikhil Bansal , Raghvendra Narayan Subacute sclerosing panencephalitis (SSPE) is a progressive neurological disorder characterized by behavioral changes, myoclonus, dementia, visual disturbances, pyramidal and extra pyramidal signs. The disease has a gradual progressive course leading to death within few years of its onset. SSPE in a child who has received measles vaccine and having no clinically apparent measles in the past is a rare occurrence. Although these type of cases have been reported worldwide its pathogenesis is still not well established. Many authors linked it to be due to mutant strain of measles virus and some it to its live vaccines. To our knowledge there are very scant literature from India about such cases so here we are reporting this case in an 8-year-old girl child.
Source: Pediatric Infectious Disease - Category: Pediatrics Source Type: research