Multiple erythematous penile erosions in a preschool child: An unusual presentation of common infection
We report an uncommon manifestation of candidiasis presenting as multiple erythematous penile erosions in a preschool child. The 4 year old boy presented with painful, reddish ulcers in the glans penis and mucosa of prepuce for 3 days without any history of itching or fever. KOH mount from the lesion revealed numerous budding yeasts and child responded well to antifungal therapy. As such presentation is uncommon, high index of suspicion is required to clinch the diagnosis. (Source: Pediatric Infectious Disease)
Source: Pediatric Infectious Disease - October 13, 2014 Category: Pediatrics Source Type: research

Ciprofloxacin and imipenem for Chryseobacterium indologenes presumed meningitis in a preterm neonate
Publication date: Available online 18 June 2014 Source:Pediatric Infectious Disease Author(s): Elizabeth L. Alford , Chasity M. Shelton Chryseobacterium species are a rarely reported cause of meningitis in neonates, but treatment can be difficult as drug resistance is common. This case report describes the management of presumed meningitis using ciprofloxacin and imipenem in a preterm neonate with renal dysfunction and blood cultures positive for Chryseobacterium indologenes. The dosing for both antibiotics was especially challenging due to the lack of available information regarding appropriate dosage adjustment in...
Source: Pediatric Infectious Disease - October 13, 2014 Category: Pediatrics Source Type: research

Febrile neutropenia in pediatric cancer patients: Experience from a tertiary health care facility of Pakistan
Conclusion Prospective studies in large cooperative trials may be beneficial in evaluating these risk factors further. (Source: Pediatric Infectious Disease)
Source: Pediatric Infectious Disease - October 13, 2014 Category: Pediatrics Source Type: research

“Infantile botulism: Forgotten etiology of acute hypotonia in infancy”
We report here the effectiveness and safety of equine botulinum antitoxin (EqBA) as an alternative treatment of infantile botulism. (Source: Pediatric Infectious Disease)
Source: Pediatric Infectious Disease - October 13, 2014 Category: Pediatrics Source Type: research

Plasmablastic lymphoma of bone in a human immunodeficiency virus positive child – A rare extra-oral presentation
We report the case of a ten year old girl presenting with multiple bone lesions and hepatosplenomegaly. Histopathology and immunophenotyping was suggestive of PBL. ELISA for HIV 1 was reactive. Despite her advanced stage at presentation, she responded well to Highly Active Anti Retroviral Therapy (HAART) and six cycles of chemotherapy (CHOP). She is continued on HAART and is on follow-up for 38 months. (Source: Pediatric Infectious Disease)
Source: Pediatric Infectious Disease - October 13, 2014 Category: Pediatrics Source Type: research

Anthrax meningo-encephalitis in a neonate
We report a 28 day old male infant, youngest of all reported Indian anthrax patients with Cutaneous anthrax which disseminated and lead to fatal anthrax meningo-encephalitis. The child's parents or siblings did not report contact with dead animals or animal by-products. Mechanical transmission through insect bite was the likely route for acquisition of this infection by the infant. (Source: Pediatric Infectious Disease)
Source: Pediatric Infectious Disease - October 13, 2014 Category: Pediatrics Source Type: research

Herpes zoster in a six month old infant: A case report
Publication date: Available online 1 October 2014 Source:Pediatric Infectious Disease Author(s): Emy Abi Thomas , Abhilasha Williams Herpes zoster occurs due to reactivation of the latent varicella zoster virus and is usually a disease of the elderly. Infantile herpes zoster is believed to be rare, though recent reports suggests an increasing incidence in infants. Here we report a six month old immunocompetent infant with herpes zoster whose mother had varicella during antenatal period. (Source: Pediatric Infectious Disease)
Source: Pediatric Infectious Disease - October 13, 2014 Category: Pediatrics Source Type: research

Diagnostic utility of dengue NS1 antigen
This article reviews the various NS1 antigen tests available. The overall sensitivities were 72.3% for the pan-E Early ELISA test, 83.6% for the Platelia™ NS1 kit, and 89.6% for the NS1 Ag Strip kit. Specificities were 100%, 98.7% and 99.1% for the PanBio kit, for the Platelia™ NS1 kit and for the NS1 Ag Strip, respectively, Positive predictive values were 98.3%, 99.5% and 100% for the Platelia™ NS1, NS1 Ag Strip and pan-E Early ELISA tests respectively. However, the pan-E Early ELISA showed the lowest negative predictive value (78.3%), followed by the Platelia™ NS1 test with 86.3% and the NS1 Ag Strip with 91.1%. ...
Source: Pediatric Infectious Disease - October 13, 2014 Category: Pediatrics Source Type: research