Typhoid fever complicated with hemophagocytic syndrome in an 11-year-old child
We report here the case of an 11-year-old child who has developed a hemophagocytic syndrome secondary to typhoid fever which has been managed successfully by antibacterial therapy alone without the need of intensive therapy. (Source: Pediatric Infectious Disease)
Source: Pediatric Infectious Disease - December 12, 2015 Category: Pediatrics Source Type: research

Laboratory investigations can be double-edged swords
Publication date: Available online 17 November 2015 Source:Pediatric Infectious Disease Author(s): Yash Paul (Source: Pediatric Infectious Disease)
Source: Pediatric Infectious Disease - December 4, 2015 Category: Pediatrics Source Type: research

Encephalitis outbreaks in India: A cluttered landscape
Publication date: Available online 2 December 2015 Source:Pediatric Infectious Disease Author(s): Vipin M Vashishtha (Source: Pediatric Infectious Disease)
Source: Pediatric Infectious Disease - December 3, 2015 Category: Pediatrics Source Type: research

Scrub typhus: A rare cause of encephalitis in pediatric age group
We present a case of a 4-year-old child from Delhi presenting with hepatosplenomegaly, thrombocytopenia, and altered sensorium, whose timely diagnosis and management saved her life, and this brings to our notice the emergence of scrub encephalitis in children. (Source: Pediatric Infectious Disease)
Source: Pediatric Infectious Disease - November 29, 2015 Category: Pediatrics Source Type: research

Spontaneous remission of acute myeloblastic leukemia with improvement in CD4 counts in HIV-infected child co-infested with Demodex mite
We present an 11-year-old HIV-infected boy who developed acute myeloid leukemia that showed spontaneous remission along with improvement in CD4 counts with documented Demodex mite infestation. The child presented with fever without localization during course of illness, and developed crusted lesion at angle of mouth. Direct microscopy of skin biopsy revealed Demodex mite infestation. The child was continued on highly active antiretroviral treatment along with single dose of ivermectin and local application of permethrin. The crusted lesion improved within a weeks’ time. His CD4 counts improved from baseline of 534/μL to...
Source: Pediatric Infectious Disease - November 27, 2015 Category: Pediatrics Source Type: research

Sacral Herpes Zoster Causing Acute Urinary Retention
We report a 12-year-old girl presented with urinary retention due to varicella zoster virus infection involving the sacral nerves. The perineum over dermatomes S2 - S4 on the left was involved with a vesicular and superficially erosive rash. Initial management included urethral catheterization as well as full course of oral acyclovir therapy. At follow-up 4 weeks later, the perineal skin lesions had healed, the catheter was removed and the patient was able to pass urine. (Source: Pediatric Infectious Disease)
Source: Pediatric Infectious Disease - November 27, 2015 Category: Pediatrics Source Type: research

Rickettsial infections
Publication date: Available online 27 November 2015 Source:Pediatric Infectious Disease Author(s): Atul A. Kulkarni (Source: Pediatric Infectious Disease)
Source: Pediatric Infectious Disease - November 27, 2015 Category: Pediatrics Source Type: research

Empyema thoracis with acute glomerulonephritis: a rare concurrence and etiological enigma
Publication date: Available online 27 November 2015 Source:Pediatric Infectious Disease Author(s): Vishnu Kumar Goyal, Sandeep Choudhary, N P Chhangani, Akash Sharma We are reporting a five year male child of empyema thoracis, who developed acute glomeruolnephritis as a complication. Post infectious glomeruolnephritis in children commonly follows group A β-hemolytic streptococcal infections. Development of nephritis in empyema is rare in children. (Source: Pediatric Infectious Disease)
Source: Pediatric Infectious Disease - November 27, 2015 Category: Pediatrics Source Type: research

Laboratory Investigations can be double edged swords
Publication date: Available online 17 November 2015 Source:Pediatric Infectious Disease Author(s): Yash Paul (Source: Pediatric Infectious Disease)
Source: Pediatric Infectious Disease - November 17, 2015 Category: Pediatrics Source Type: research

Atypical presentation of scrub typhus in children
We report a rare case of scrub typhus presenting with refractory seizures in a 9year old child, not previously reported in children from India. (Source: Pediatric Infectious Disease)
Source: Pediatric Infectious Disease - November 10, 2015 Category: Pediatrics Source Type: research

Clinico-laboratory profile of Scrub Typhus from mid and lower Himalayan region in north India
Conclusion Scrub typhus has emerged as an important cause of febrile illness with multi-systemic involvement and high rate of MODS. (Source: Pediatric Infectious Disease)
Source: Pediatric Infectious Disease - November 10, 2015 Category: Pediatrics Source Type: research

Scrub typhus: a rare cause of encehalitis in pediatric age group
We present a case of 4 year old child from Delhi presenting with hepatosplenomegaly, thrombocytopenia, altered sensorium, whose timely diagnosis and management saved her life and brings to our notice the emergence of scrub encephalitis in children. (Source: Pediatric Infectious Disease)
Source: Pediatric Infectious Disease - November 10, 2015 Category: Pediatrics Source Type: research

Spontaneous remission of acute myeloblastic leukemia with improvement in CD 4 counts in HIV infected child co-infested with Demodex Mite
We present an 11 year old HIV infected boy who developed acute myeloid leukemia that showed spontaneous remission along with improvement in CD4 counts with documented Demodex mite infestation. The child presented with fever without localization during course of illness, developed crusted lesion at angle of mouth. Direct microscopy of skin biopsy revealed demodex mite infestation. Child was continued on highly active antiretroviral treatment along with single dose of ivermectin and local application of permethrin. The crusted lesion improved within a weeks’ time. His CD4 counts improved from baseline of 534/μL to 1674/μ...
Source: Pediatric Infectious Disease - November 10, 2015 Category: Pediatrics Source Type: research

Current Challenges and Future Perspectives in Neonatal Sepsis
Publication date: Available online 10 November 2015 Source:Pediatric Infectious Disease Author(s): S Kingsley Manoj Kumar, B. Vishnu Bhat Sepsis poses a great threat to the newborns and different approaches are in practice to tackle this problem. The signs and symptoms of neonatal sepsis are non-specific and this makes accurate diagnosis difficult. Commonly used biomarkers such as acute phase reactants and cytokines have not been completely conclusive though they have shown some promise. Newer approaches such as flow cytometry and real time PCR could be valuable tools for the timely diagnosis and management of neon...
Source: Pediatric Infectious Disease - November 10, 2015 Category: Pediatrics Source Type: research

An unusual case of Typhus group rickettsial infection presenting as cerebrovascular stroke.
Publication date: Available online 10 November 2015 Source:Pediatric Infectious Disease Author(s): C L Srinivasa Murthy, P Namitha, K Raghavendra, Naveen Kumar, Rajath Pejaver Rickettsial diseases are a group of infections caused by obligate intracellular gram negative bacilli and transmitted to man by arthropod vectors. They are prevalent in many parts in India and are characterized by microvasculitis, causing microinfarcts in various organs 1). Complications of rickettsial infection include pneumonias, renal failures and neurological involvement. Neurological complications such as meningitis and meningoence...
Source: Pediatric Infectious Disease - November 10, 2015 Category: Pediatrics Source Type: research