Spontaneous remission of acute myeloblastic leukemia with improvement in CD 4 counts in HIV infected child co-infested with Demodex Mite

We present an 11 year old HIV infected boy who developed acute myeloid leukemia that showed spontaneous remission along with improvement in CD4 counts with documented Demodex mite infestation. The child presented with fever without localization during course of illness, developed crusted lesion at angle of mouth. Direct microscopy of skin biopsy revealed demodex mite infestation. Child was continued on highly active antiretroviral treatment along with single dose of ivermectin and local application of permethrin. The crusted lesion improved within a weeks’ time. His CD4 counts improved from baseline of 534/μL to 1674/μL over a period of 4 weeks.
Source: Pediatric Infectious Disease - Category: Pediatrics Source Type: research