LETTER TO THE EDITOR Atypical Granulomatous Myositis and Pulmonary Sarcoidosis.
Authors: Scalco RS, Brady S, Becker J, Gomes I, Holton JL, Staub HL
PMID: 26312107 [PubMed - as supplied by publisher] (Source: Open Rheumatology Journal)
Source: Open Rheumatology Journal - August 28, 2015 Category: Rheumatology Tags: Open Rheumatol J Source Type: research
A Case Report of Successful Treatment of Recalcitrant Childhood Localized Scleroderma with Infliximab and Leflunomide.
Authors: Ferguson ID, Weiser P, Torok KS
Abstract
Herein we report successful treatment of an adolescent Caucasian female with severe progressive localized scleroderma (mixed subtype, including generalized morphea and linear scleroderma of the trunk/limb) using infliximab and leflunomide. The patient demonstrated improvement after the first 9 months of therapy based on her clinical examination, objective measures, and patient and parent global assessments. Infliximab is a potential treatment option for pediatric localized scleroderma patients who have progression of disease or who are unable to tolerate th...
Source: Open Rheumatology Journal - July 13, 2015 Category: Rheumatology Tags: Open Rheumatol J Source Type: research
Clinical Characteristics and Outcome of Primary Sjogren's Syndrome: A Large Asian Indian Cohort.
CONCLUSION: Our cohort of patients with SS has characteristic clinical features; some of them are in contrast with previous observations reported in European patients. This cohort consisted of two distinct patient clusters. The first cluster was associated with major systemic illness and high antibody titers, where as the second cluster comprised of seronegative patients with mild disease. Association of antibody positivity with systemic features was further confirmed on logistic regression analysis.
PMID: 26161156 [PubMed] (Source: Open Rheumatology Journal)
Source: Open Rheumatology Journal - July 13, 2015 Category: Rheumatology Tags: Open Rheumatol J Source Type: research
Diagnosis and Treatment of Acute Gout at a University Hospital Emergency Department.
CONCLUSION: The diagnosis of acute gout in the ED is commonly clinical and not crystal proven. Anti-inflammatory drugs are the mainstay of treatment in acute gout; yet, during more than 50% of ED visits, anti-inflammatory drugs were not given during the visit. Thus, improvement in the diagnosis and treatment of acute gout in the ED may be required.
PMID: 26106456 [PubMed] (Source: Open Rheumatology Journal)
Source: Open Rheumatology Journal - June 26, 2015 Category: Rheumatology Tags: Open Rheumatol J Source Type: research
An Unusual Mimicker of Systemic Lupus Erythematosus: A Case Report.
We present a case of a 47 year-old African American female with 15 pack-years of tobacco use and heavy alcohol use who presented with arthritis and was found to have a positive antinuclear antibodies (ANA), anti double stranded DNA antibodies (anti-dsDNA), and anti-Sjogren's syndrome-related antigen A and antigen B (anti-SSA and anti-SSB). She was subsequently found to have a lung adenocarcinoma associated with hypertrophic pulmonary osteoarthropathy (HPO). This demonstrates a case of positive antinuclear antibodies and arthritis in a patient with lung adenocarcinoma, which can be falsely diagnosed as systemic lupus erythe...
Source: Open Rheumatology Journal - June 26, 2015 Category: Rheumatology Tags: Open Rheumatol J Source Type: research
Development of Canadian Recommendations for the Management of ANCA-Associated Vasculitides: Results of the National Needs Assessment Questionnaire.
CONCLUSION: Practice variations identified in this needs assessment survey will serve to formulate key questions for the development of CanVasc recommendations.
PMID: 25893028 [PubMed] (Source: Open Rheumatology Journal)
Source: Open Rheumatology Journal - April 23, 2015 Category: Rheumatology Tags: Open Rheumatol J Source Type: research
Comparisons of Body Image Perceptions of a Sample of Black and White Women with Rheumatoid Arthritis and Fibromyalgia in the US.
CONCLUSION: The body image perceptions evidenced by the majority of participants were generally negative and included specific focus on their disease-affected body parts (e.g. joints), mental function, self-identity, health care experiences, activity limitations and overall quality of life. Given the global effect of RA and FM, assessment and integration of findings about the BI perceptions of individuals with FM and RA may help define suitable interdisciplinary strategies for managing these conditions and improving participants' quality of life.
PMID: 25674181 [PubMed] (Source: Open Rheumatology Journal)
Source: Open Rheumatology Journal - February 14, 2015 Category: Rheumatology Tags: Open Rheumatol J Source Type: research
Comparing Five Year Out-Come in Two Cohorts of Patients with Early Rheumatoid Arthritis - A BARFOT Study.
CONCLUSION: Patients included in the 2000s achieved higher frequency of remission at the 5 year follow-up compared with those included in the 1990s, suggested to reflect the more active medical treatment. Interestingly, however, improvement in pain and HAQ did not differ between the two patient cohorts.
PMID: 25674182 [PubMed] (Source: Open Rheumatology Journal)
Source: Open Rheumatology Journal - February 14, 2015 Category: Rheumatology Tags: Open Rheumatol J Source Type: research
Felty's Syndrome, Insights and Updates.
Authors: Owlia MB, Newman K, Akhtari M
Abstract
Felty's syndrome (FS) is characterized by the triad of seropositive rheumatoid arthritis (RA) with destructive joint involvement, splenomegaly and neutropenia. Current data shows that 1-3 % of RA patients are complicated with FS with an estimated prevalence of 10 per 100,000 populations. The complete triad is not an absolute requirement, but persistent neutropenia with an absolute neutrophil count (ANC) generally less than 1500/mm3 is necessary for establishing the diagnosis. Felty's syndrome may be asymptomatic but serious local or systemic infections may be...
Source: Open Rheumatology Journal - January 25, 2015 Category: Rheumatology Tags: Open Rheumatol J Source Type: research
Osteoarthritis at young age, a diagnostic challenge: a case of stickler syndrome.
Authors: de Wergifosse I, Westhovens R
Abstract
A young woman presents with severe polyarticular osteoarthritis with relevant family history potentially suggesting a hereditary disease. Previously, the patient's mother had been diagnosed with rheumatoid arthritis and reported to have suffered from some locomotor problems. Careful clinical evaluation with an extensive personal and familial history pointed towards a diagnosis of Stickler syndrome, an autosomal dominant condition with progressive arthro-ophthalmopathy, (early osteoarthritis and myopia). Following this timely diagnosis, genetic counselling was...
Source: Open Rheumatology Journal - January 20, 2015 Category: Rheumatology Tags: Open Rheumatol J Source Type: research
Monitoring complete blood counts and haemoglobin levels in osteoarthritis patients: results from a European survey investigating primary care physician behaviours and understanding.
CONCLUSION: Physician practice in relation to carrying out blood tests in OA patients and their understanding of the potential significance of specific results obtained, namely haemoglobin values, varies substantially across the countries surveyed. As NSAIDs form a pivotal part in the chronic treatment of osteoarthritis and are well recognised agents that can precipitate blood loss, guidelines may be needed to advise physicians as to when monitoring a patient's haemoglobin levels may be appropriate.
PMID: 25598854 [PubMed] (Source: Open Rheumatology Journal)
Source: Open Rheumatology Journal - January 20, 2015 Category: Rheumatology Tags: Open Rheumatol J Source Type: research
Metabolic factors in diffuse idiopathic skeletal hyperostosis - a review of clinical data.
CONCLUSION: Current research indicates that certain metabolic factors associate with DISH. More precise studies deriving from these findings on these and other newly identified bone-growth factors are needed.
PMID: 25598855 [PubMed] (Source: Open Rheumatology Journal)
Source: Open Rheumatology Journal - January 20, 2015 Category: Rheumatology Tags: Open Rheumatol J Source Type: research
Sjögren's, Renal Tubular Acidosis And Osteomalacia - An Asian Indian Series.
CONCLUSION: Most patients were asymptomatic for RTA inspite of clinically overt and elicitable features. Skeletal manifestation was a common finding in patients with Sjögren and RTA, despite normal levels of 25 (OH) D3 in a majority.
PMID: 25584094 [PubMed] (Source: Open Rheumatology Journal)
Source: Open Rheumatology Journal - January 15, 2015 Category: Rheumatology Tags: Open Rheumatol J Source Type: research
A positive association between foot posture index and medial compartment knee osteoarthritis in moroccan people.
CONCLUSION: Pronated foot posture and flat foot are significantly associated with medial compartment knee osteoarthritis.
PMID: 25553141 [PubMed] (Source: Open Rheumatology Journal)
Source: Open Rheumatology Journal - January 2, 2015 Category: Rheumatology Tags: Open Rheumatol J Source Type: research
Physical Exercise and Weight Loss for Hip and Knee Osteoarthritis in Very Old Patients: A Systematic Review of the Literature.
CONCLUSION: Our systematic review confirms that international recommendations on exercise for knee osteoarthritis also apply to subjects aged 70-80 years. Long-term effectiveness requires a maintenance strategy. Specific trials on very old patients with various comorbidities are mandatory, given that these subjects are more exposed to drug-related iatrogenesis.
PMID: 25489352 [PubMed - as supplied by publisher] (Source: Open Rheumatology Journal)
Source: Open Rheumatology Journal - December 11, 2014 Category: Rheumatology Tags: Open Rheumatol J Source Type: research
