Marginal zone B cells control the response of follicular helper T cells to a high-cholesterol diet
Nature Medicine 23, 601 (2017).
doi:10.1038/nm.4315
Authors: Meritxell Nus, Andrew P Sage, Yuning Lu, Leanne Masters, Brian Y H Lam, Stephen Newland, Sandra Weller, Dimitrios Tsiantoulas, Juliette Raffort, Damiënne Marcus, Alison Finigan, Lauren Kitt, Nichola Figg, Reinhold Schirmbeck, Manfred Kneilling, Giles S H Yeo, Christoph J Binder, José Luis de la Pompa & Ziad Mallat (Source: Nature Medicine)
Source: Nature Medicine - April 17, 2017 Category: General Medicine Authors: Meritxell Nus Andrew P Sage Yuning Lu Leanne Masters Brian Y H Lam Stephen Newland Sandra Weller Dimitrios Tsiantoulas Juliette Raffort Dami ë nne Marcus Alison Finigan Lauren Kitt Nichola Figg Reinhold Schirmbeck Manfred Kneilling Giles S H Yeo Christop Tags: Article Source Type: research
HIV persistence in tissue macrophages of humanized myeloid-only mice during antiretroviral therapy
Nature Medicine 23, 638 (2017).
doi:10.1038/nm.4319
Authors: Jenna B Honeycutt, William O Thayer, Caroline E Baker, Ruy M Ribeiro, Steven M Lada, Youfang Cao, Rachel A Cleary, Michael G Hudgens, Douglas D Richman & J Victor Garcia
Despite years of fully suppressive antiretroviral therapy (ART), HIV persists in its hosts and is never eradicated. One major barrier to eradication is that the virus infects multiple cell types that may individually contribute to HIV persistence. Tissue macrophages are critical contributors to HIV pathogenesis; however, their specific role in HIV persistence during long-term suppress...
Source: Nature Medicine - April 17, 2017 Category: Journals (General) Authors: Jenna B Honeycutt William O Thayer Caroline E Baker Ruy M Ribeiro Steven M Lada Youfang Cao Rachel A Cleary Michael G Hudgens Douglas D Richman J Victor Garcia Tags: Letter Source Type: research
Alternatively activated macrophages do not synthesize catecholamines or contribute to adipose tissue adaptive thermogenesis
Nature Medicine 23, 623 (2017).
doi:10.1038/nm.4316
Authors: Katrin Fischer, Henry H Ruiz, Kevin Jhun, Brian Finan, Douglas J Oberlin, Verena van der Heide, Anastasia V Kalinovich, Natasa Petrovic, Yochai Wolf, Christoffer Clemmensen, Andrew C Shin, Senad Divanovic, Frank Brombacher, Elke Glasmacher, Susanne Keipert, Martin Jastroch, Joachim Nagler, Karl-Werner Schramm, Dasa Medrikova, Gustav Collden, Stephen C Woods, Stephan Herzig, Dirk Homann, Steffen Jung, Jan Nedergaard, Barbara Cannon, Matthias H Tschöp, Timo D Müller & Christoph Buettner (Source: Nature Medicine)
Source: Nature Medicine - April 17, 2017 Category: Journals (General) Authors: Katrin Fischer Henry H Ruiz Kevin Jhun Brian Finan Douglas J Oberlin Verena van der Heide Anastasia V Kalinovich Natasa Petrovic Yochai Wolf Christoffer Clemmensen Andrew C Shin Senad Divanovic Frank Brombacher Elke Glasmacher Susanne Keipert Martin Jastr Tags: Article Source Type: research
Marginal zone B cells control the response of follicular helper T cells to a high-cholesterol diet
Nature Medicine 23, 601 (2017).
doi:10.1038/nm.4315
Authors: Meritxell Nus, Andrew P Sage, Yuning Lu, Leanne Masters, Brian Y H Lam, Stephen Newland, Sandra Weller, Dimitrios Tsiantoulas, Juliette Raffort, Damiënne Marcus, Alison Finigan, Lauren Kitt, Nichola Figg, Reinhold Schirmbeck, Manfred Kneilling, Giles S H Yeo, Christoph J Binder, José Luis de la Pompa & Ziad Mallat (Source: Nature Medicine)
Source: Nature Medicine - April 17, 2017 Category: Journals (General) Authors: Meritxell Nus Andrew P Sage Yuning Lu Leanne Masters Brian Y H Lam Stephen Newland Sandra Weller Dimitrios Tsiantoulas Juliette Raffort Dami ënne Marcus Alison Finigan Lauren Kitt Nichola Figg Reinhold Schirmbeck Manfred Kneilling Giles S H Yeo Christoph Tags: Article Source Type: research
A live-attenuated Zika virus vaccine candidate induces sterilizing immunity in mouse models
Nature Medicine 23, 763 (2017).
doi:10.1038/nm.4322
Authors: Chao Shan, Antonio E Muruato, Bruno T D Nunes, Huanle Luo, Xuping Xie, Daniele B A Medeiros, Maki Wakamiya, Robert B Tesh, Alan D Barrett, Tian Wang, Scott C Weaver, Pedro F C Vasconcelos, Shannan L Rossi & Pei-Yong Shi
Zika virus (ZIKV) infection of pregnant women can cause a wide range of congenital abnormalities, including microcephaly, in the infant, a condition now collectively known as congenital ZIKV syndrome. A vaccine to prevent or significantly attenuate viremia in pregnant women who are residents of or travelers to epidemic or endemic regio...
Source: Nature Medicine - April 10, 2017 Category: General Medicine Authors: Chao Shan Antonio E Muruato Bruno T D Nunes Huanle Luo Xuping Xie Daniele B A Medeiros Maki Wakamiya Robert B Tesh Alan D Barrett Tian Wang Scott C Weaver Pedro F C Vasconcelos Shannan L Rossi Pei-Yong Shi Tags: Letter Source Type: research
MAFB prevents excess inflammation after ischemic stroke by accelerating clearance of damage signals through MSR1
Nature Medicine 23, 723 (2017).
doi:10.1038/nm.4312
Authors: Takashi Shichita, Minako Ito, Rimpei Morita, Kyoko Komai, Yoshiko Noguchi, Hiroaki Ooboshi, Ryusuke Koshida, Satoru Takahashi, Tatsuhiko Kodama & Akihiko Yoshimura (Source: Nature Medicine)
Source: Nature Medicine - April 10, 2017 Category: General Medicine Authors: Takashi Shichita Minako Ito Rimpei Morita Kyoko Komai Yoshiko Noguchi Hiroaki Ooboshi Ryusuke Koshida Satoru Takahashi Tatsuhiko Kodama Akihiko Yoshimura Tags: Article Source Type: research
A heart – brain – kidney network controls adaptation to cardiac stress through tissue macrophage activation
Nature Medicine 23, 611 (2017).
doi:10.1038/nm.4326
Authors: Katsuhito Fujiu, Munehiko Shibata, Yukiteru Nakayama, Fusa Ogata, Sahohime Matsumoto, Koji Noshita, Shingo Iwami, Susumu Nakae, Issei Komuro, Ryozo Nagai & Ichiro Manabe (Source: Nature Medicine)
Source: Nature Medicine - April 10, 2017 Category: General Medicine Authors: Katsuhito Fujiu Munehiko Shibata Yukiteru Nakayama Fusa Ogata Sahohime Matsumoto Koji Noshita Shingo Iwami Susumu Nakae Issei Komuro Ryozo Nagai Ichiro Manabe Tags: Article Source Type: research
Thymosin α 1 represents a potential potent single-molecule-based therapy for cystic fibrosis
Nature Medicine 23, 590 (2017).
doi:10.1038/nm.4305
Authors: Luigina Romani, Vasilis Oikonomou, Silvia Moretti, Rossana G Iannitti, Maria Cristina D'Adamo, Valeria R Villella, Marilena Pariano, Luigi Sforna, Monica Borghi, Marina M Bellet, Francesca Fallarino, Maria Teresa Pallotta, Giuseppe Servillo, Eleonora Ferrari, Paolo Puccetti, Guido Kroemer, Mauro Pessia, Luigi Maiuri, Allan L Goldstein & Enrico Garaci (Source: Nature Medicine)
Source: Nature Medicine - April 10, 2017 Category: General Medicine Authors: Luigina Romani Vasilis Oikonomou Silvia Moretti Rossana G Iannitti Maria Cristina D'Adamo Valeria R Villella Marilena Pariano Luigi Sforna Monica Borghi Marina M Bellet Francesca Fallarino Maria Teresa Pallotta Giuseppe Servillo Eleonora Ferrari Paolo Puc Tags: Article Source Type: research
A stemness-related ZEB1 – MSRB3 axis governs cellular pliancy and breast cancer genome stability
Nature Medicine 23, 568 (2017).
doi:10.1038/nm.4323
Authors: Anne-Pierre Morel, Christophe Ginestier, Roxane M Pommier, Olivier Cabaud, Emmanuelle Ruiz, Julien Wicinski, Mojgan Devouassoux-Shisheboran, Valérie Combaret, Pascal Finetti, Christelle Chassot, Christiane Pinatel, Frédérique Fauvet, Pierre Saintigny, Emilie Thomas, Caroline Moyret-Lalle, Joël Lachuer, Emmanuelle Despras, Jean-Luc Jauffret, François Bertucci, Jérôme Guitton, Anne Wierinckx, Qing Wang, Nina Radosevic-Robin, Frédérique Penault-Llorca, David G Cox, Frédéric Hollande, Stéphane Ansiea...
Source: Nature Medicine - April 10, 2017 Category: General Medicine Authors: Anne-Pierre Morel Christophe Ginestier Roxane M Pommier Olivier Cabaud Emmanuelle Ruiz Julien Wicinski Mojgan Devouassoux-Shisheboran Val é rie Combaret Pascal Finetti Christelle Chassot Christiane Pinatel Fr é d é rique Fauvet Pierre Saintigny Emilie Tags: Article Source Type: research
Dectin 1 activation on macrophages by galectin 9 promotes pancreatic carcinoma and peritumoral immune tolerance
Nature Medicine 23, 556 (2017).
doi:10.1038/nm.4314
Authors: Donnele Daley, Vishnu R Mani, Navyatha Mohan, Neha Akkad, Atsuo Ochi, Daniel W Heindel, Ki Buom Lee, Constantinos P Zambirinis, Gautam SD Balasubramania Pandian, Shivraj Savadkar, Alejandro Torres-Hernandez, Shruti Nayak, Ding Wang, Mautin Hundeyin, Brian Diskin, Berk Aykut, Gregor Werba, Rocky M Barilla, Robert Rodriguez, Steven Chang, Lawrence Gardner, Lara K Mahal, Beatrix Ueberheide & George Miller (Source: Nature Medicine)
Source: Nature Medicine - April 10, 2017 Category: General Medicine Authors: Donnele Daley Vishnu R Mani Navyatha Mohan Neha Akkad Atsuo Ochi Daniel W Heindel Ki Buom Lee Constantinos P Zambirinis Gautam SD Balasubramania Pandian Shivraj Savadkar Alejandro Torres-Hernandez Shruti Nayak Ding Wang Mautin Hundeyin Brian Diskin Berk A Tags: Article Source Type: research
A heart –brain–kidney network controls adaptation to cardiac stress through tissue macrophage activation
Nature Medicine 23, 611 (2017).
doi:10.1038/nm.4326
Authors: Katsuhito Fujiu, Munehiko Shibata, Yukiteru Nakayama, Fusa Ogata, Sahohime Matsumoto, Koji Noshita, Shingo Iwami, Susumu Nakae, Issei Komuro, Ryozo Nagai & Ichiro Manabe (Source: Nature Medicine)
Source: Nature Medicine - April 10, 2017 Category: Journals (General) Authors: Katsuhito Fujiu Munehiko Shibata Yukiteru Nakayama Fusa Ogata Sahohime Matsumoto Koji Noshita Shingo Iwami Susumu Nakae Issei Komuro Ryozo Nagai Ichiro Manabe Tags: Article Source Type: research
Thymosin α1 represents a potential potent single-molecule-based therapy for cystic fibrosis
Nature Medicine 23, 590 (2017).
doi:10.1038/nm.4305
Authors: Luigina Romani, Vasilis Oikonomou, Silvia Moretti, Rossana G Iannitti, Maria Cristina D'Adamo, Valeria R Villella, Marilena Pariano, Luigi Sforna, Monica Borghi, Marina M Bellet, Francesca Fallarino, Maria Teresa Pallotta, Giuseppe Servillo, Eleonora Ferrari, Paolo Puccetti, Guido Kroemer, Mauro Pessia, Luigi Maiuri, Allan L Goldstein & Enrico Garaci (Source: Nature Medicine)
Source: Nature Medicine - April 10, 2017 Category: Journals (General) Authors: Luigina Romani Vasilis Oikonomou Silvia Moretti Rossana G Iannitti Maria Cristina D'Adamo Valeria R Villella Marilena Pariano Luigi Sforna Monica Borghi Marina M Bellet Francesca Fallarino Maria Teresa Pallotta Giuseppe Servillo Eleonora Ferrari Paolo Puc Tags: Article Source Type: research
A stemness-related ZEB1 –MSRB3 axis governs cellular pliancy and breast cancer genome stability
Nature Medicine 23, 568 (2017).
doi:10.1038/nm.4323
Authors: Anne-Pierre Morel, Christophe Ginestier, Roxane M Pommier, Olivier Cabaud, Emmanuelle Ruiz, Julien Wicinski, Mojgan Devouassoux-Shisheboran, Valérie Combaret, Pascal Finetti, Christelle Chassot, Christiane Pinatel, Frédérique Fauvet, Pierre Saintigny, Emilie Thomas, Caroline Moyret-Lalle, Joël Lachuer, Emmanuelle Despras, Jean-Luc Jauffret, François Bertucci, Jérôme Guitton, Anne Wierinckx, Qing Wang, Nina Radosevic-Robin, Frédérique Penault-Llorca, David G Cox, Frédéric Hollande, Stéphane Ansiea...
Source: Nature Medicine - April 10, 2017 Category: Journals (General) Authors: Anne-Pierre Morel Christophe Ginestier Roxane M Pommier Olivier Cabaud Emmanuelle Ruiz Julien Wicinski Mojgan Devouassoux-Shisheboran Val érie Combaret Pascal Finetti Christelle Chassot Christiane Pinatel Fr édérique Fauvet Pierre Saintigny Emilie Thom Tags: Article Source Type: research
Dectin 1 activation on macrophages by galectin 9 promotes pancreatic carcinoma and peritumoral immune tolerance
Nature Medicine 23, 556 (2017).
doi:10.1038/nm.4314
Authors: Donnele Daley, Vishnu R Mani, Navyatha Mohan, Neha Akkad, Atsuo Ochi, Daniel W Heindel, Ki Buom Lee, Constantinos P Zambirinis, Gautam SD Balasubramania Pandian, Shivraj Savadkar, Alejandro Torres-Hernandez, Shruti Nayak, Ding Wang, Mautin Hundeyin, Brian Diskin, Berk Aykut, Gregor Werba, Rocky M Barilla, Robert Rodriguez, Steven Chang, Lawrence Gardner, Lara K Mahal, Beatrix Ueberheide & George Miller (Source: Nature Medicine)
Source: Nature Medicine - April 10, 2017 Category: Journals (General) Authors: Donnele Daley Vishnu R Mani Navyatha Mohan Neha Akkad Atsuo Ochi Daniel W Heindel Ki Buom Lee Constantinos P Zambirinis Gautam SD Balasubramania Pandian Shivraj Savadkar Alejandro Torres-Hernandez Shruti Nayak Ding Wang Mautin Hundeyin Brian Diskin Berk A Tags: Article Source Type: research
Erratum: PIM1 kinase regulates cell death, tumor growth and chemotherapy response in triple-negative breast cancer
Nature Medicine 23, 526 (2017).
doi:10.1038/nm0417-526c
Authors: Fara Brasó-Maristany, Simone Filosto, Steven Catchpole, Rebecca Marlow, Jelmar Quist, Erika Francesch-Domenech, Darren A Plumb, Leila Zakka, Patrycja Gazinska, Gianmaria Liccardi, Pascal Meier, Albert Gris-Oliver, Maggie Chon U Cheang, Anna Perdrix-Rosell, Manar Shafat, Elodie Noël, Nirmesh Patel, Kristen McEachern, Maurizio Scaltriti, Pau Castel, Farzana Noor, Richard Buus, Sumi Mathew, Johnathan Watkins, Violeta Serra, Pierfrancesco Marra, Anita Grigoriadis & Andrew N Tutt (Source: Nature Medicine)
Source: Nature Medicine - April 7, 2017 Category: Journals (General) Authors: Fara Bras ó-Maristany Simone Filosto Steven Catchpole Rebecca Marlow Jelmar Quist Erika Francesch-Domenech Darren A Plumb Leila Zakka Patrycja Gazinska Gianmaria Liccardi Pascal Meier Albert Gris-Oliver Maggie Chon U Cheang Anna Perdrix-Rosell Manar Shaf Tags: Erratum Source Type: research
