Management of aspirin intolerance in patients undergoing percutaneous coronary intervention: the role of mono-antiplatelet therapy. A retrospective, multicenter, study.
CONCLUSIONS: Our study evaluating patients with ACS or stable CAD undergoing PCI and treated with mono anti-platelet therapy with P2Y12 inhibitors due to aspirin intolerance shows a 25% incidence of POCE at one year. Further studies with adequate sample size are required to evaluate the efficacy and safety of mono anti-platelet therapy in this clinical scenario. PMID: 30895761 [PubMed - as supplied by publisher] (Source: Minerva Cardioangiologica)
Source: Minerva Cardioangiologica - March 23, 2019 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

Antihypertensive effect of sacubitril/valsartan: a meta-analysis.
CONCLUSIONS: Sacubitril/valsartan may reduce arterial pressure more efficaciously than ARBs in elderly hypertensive patients. PMID: 30895762 [PubMed - as supplied by publisher] (Source: Minerva Cardioangiologica)
Source: Minerva Cardioangiologica - March 23, 2019 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

ECG in noonan syndrome: beyond the "normal abnormalities".
Authors: Mazza GA, Banaudi E, Ferrero GB, Baldassarre G, Agnoletti G Abstract PMID: 30895763 [PubMed - as supplied by publisher] (Source: Minerva Cardioangiologica)
Source: Minerva Cardioangiologica - March 23, 2019 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

Everolimus-eluting bioresorbable vascular scaffolds: learning from the past to improve the future.
Authors: Mahtta D, Elgendy IY Abstract Bioresorbable vascular scaffolds (BVS) were developed to overcome the long-term limitations of metallic drug-eluting stents (DES). Shortcomings of DES include their permanent metallic cage which prevents normal coronary vasomotion, vascular remodeling, precludes future bypass grafting, and create a nidus for very late stent thrombosis. With its transient scaffold which provides early mechanical support and subsequently resorbs thereby restoring physiologic properties and architecture of the vasculature, BVS offers a promising development within the field of interventi...
Source: Minerva Cardioangiologica - March 23, 2019 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

Novel ultra-long (48 mm) everolimus-eluting stent for diffusely disease coronary vessels.
CONCLUSIONS: The present real-world experience shows promising clinical results with the use of ultra-long stents in order to limit the need of stents overlaps in patients with diffuse coronary disease undergoing PCI. PMID: 30895769 [PubMed - as supplied by publisher] (Source: Minerva Cardioangiologica)
Source: Minerva Cardioangiologica - March 23, 2019 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

Intravascular ultrasound-guided drug-eluting stent implantation.
Authors: Shlofmitz E, Kuku KO, Waksman R, Garcia-Garcia HM Abstract Intravascular ultrasound (IVUS) enhances diagnostic assessment with identification and characterization of plaque morphology. Determination of predominant plaque morphology prior to percutaneous coronary intervention can guide optimal treatment strategy. The transducers used with IVUS catheters include solid-state, phased array systems that have multiple stationary transducers, or rotational, mechanical IVUS systems that have a single transducer that rotates on a driveshaft. Real-time online analysis with IVUS allows determination of lumen...
Source: Minerva Cardioangiologica - March 9, 2019 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

Cardiotrophin as a prognostic factor in heart failure.
Authors: Qawoq HD, Sobczak M, Szcześniak P, Pagórek P, Miśkowiec D, Wierzbowska Drabik K, Chrzanowski Ł, Kasprzak JD Abstract PMID: 30724267 [PubMed - as supplied by publisher] (Source: Minerva Cardioangiologica)
Source: Minerva Cardioangiologica - February 7, 2019 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

Incidence of infective endocarditis before and after the guideline modification regarding a more restrictive use of prophylactic antibiotics therapy in the United States of America and Europe.
Authors: Keller K, Hobohm L, Munzel T, Ostad MA Abstract Infective endocarditis (IE) is a potentially life-threatening disease. Regardless the improvements in IE management, it remains associated with high mortality and severe complications. Staphylococci and streptococci account for 80% of all IE cases. Prevention of IE by appropriate administration of antibiotics before procedures with potential bacteremia in selected patients is recommended according to recent and current guidelines. However, recent studies, have questioned the efficacy of antimicrobial prophylaxis in special situations and in some pati...
Source: Minerva Cardioangiologica - February 7, 2019 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

Long-term rhythm monitoring with an implantable loop recorder in patients after the first clinical atrial fibrillation episode. Towards an individualized management.
Authors: Papakonstantinou PE, Simantirakis EN Abstract Although atrial fibrillation (AF) is an arrhythmia with a variable clinical profile (symptomatic and asymptomatic episodes), the first symptomatic episode leads to its initial diagnosis in most cases. Nowadays, continuous and remote long- term cardiac rhythm monitoring is feasible by the use of implantable loop recorders. The data concerning the AF recurrences and progression after the first ECG- documented clinical AF episode demonstrates that a high percentage of patients may not suffer any other AF recurrence, or may present a low recurrence rate of...
Source: Minerva Cardioangiologica - February 7, 2019 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

The prognostic value of mean platelet volume to platelet count ratio in older patients with non-ST elevation acute coronary syndrome receiving primary percutaneous coronary intervention: a retrospective study.
CONCLUSIONS: High MPV/P and MPV values are independent predictors of cardiac mortality in older patients with NSTE-ACS receive primary PCI. Moreover, MPV/P is better than MPV for predicting cardiac mortality. PMID: 30621371 [PubMed - as supplied by publisher] (Source: Minerva Cardioangiologica)
Source: Minerva Cardioangiologica - January 11, 2019 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

Clinical relevance of myocardial bridging detected by coronary CT angiography in patients with atypical chest pain.
Authors: La Grutta L, Malagò R, Toia P, Tabacco G, Smeraldi T, Albano D, Finetto G, Poletti M, Tavella D, Grassedonio E, Galia M, Cademartiri F, Pozzi Mucelli R, Midiri M Abstract PMID: 30604949 [PubMed - in process] (Source: Minerva Cardioangiologica)
Source: Minerva Cardioangiologica - January 4, 2019 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

Novel transcatheter therapies for treating tricuspid regurgitation.
Authors: Miura M, Maisano F, Zuber M, Gavazzoni M, Cuevas O, Lin SI, Ho EC, Pozzoli A, Taramasso M Abstract Until recently, tricuspid valve (TV) disease has been relatively neglected for a long time, but recently tricuspid regurgitation (TR) has attracted attention. Although the prognosis of patients with these disorders is poor, the high mortality and morbidity associated with TV surgery have resulted in many patients not receiving surgical therapy. Current guidelines recommend that TV surgery should be considered in patients with severe TR who are symptomatic or have progressive right ventricle (RV) dila...
Source: Minerva Cardioangiologica - December 1, 2018 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

Tricuspid regurgitation: from physiopathology to transcatheter interventions.
Authors: Latib A, Colombo A, Regazzoli D Abstract PMID: 30468061 [PubMed - in process] (Source: Minerva Cardioangiologica)
Source: Minerva Cardioangiologica - November 25, 2018 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

Update on cardiac implantable electronic devices: from the injectable loop recorder to the leadless pacemaker, to the subcutaneous defibrillator.
Authors: Santini M, Santini L, Di Fusco SA Abstract A very fast-paced improvement of technology in the field of cardiac implantable devices has been observed in the last ten years. The aim of this review is to highlight the most important innovations which have been recently introduced in this field, such as the leadless pacemaker (a heart stimulator without intracardiac leads), the subcutaneous defibrillator (a completely extracardiac defibrillator device), the injectable loop recorder (a miniaturized subcutaneous continuous echocardiographic monitor provided by alarms and telephonic transmission) and man...
Source: Minerva Cardioangiologica - November 25, 2018 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

Left ventricular rotational abnormalities in chloroquine-induced cardiomyopathy (from the MAGYAR-Path Study).
Authors: Nemes A, Nagy V, Domsik P, Kalapos A, Kormányos Á, Havasi K, Forster T Abstract PMID: 30468063 [PubMed - in process] (Source: Minerva Cardioangiologica)
Source: Minerva Cardioangiologica - November 25, 2018 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research