Validation of the EFFECT questionnaire for competence-based clinical teaching in residency training in Lithuania
Conclusions The results suggest that the Lithuanian version of the EFFECT maintains its original validity and may serve as a valid instrument for quality assessment of clinical teaching in competency-based residency training in Lithuania. (Source: Medicina)
Source: Medicina - May 27, 2017 Category: General Medicine Source Type: research
Ethnic variation in self-rated health –mortality association: Results from a 17-year follow-up study in Estonia
Conclusions We found considerable ethnic variation in SRH–mortality association and in socioeconomic predictors of mortality. Further research, preferably focusing on cause-specific mortality and reporting heterogeneity of SRH could potentially shed further light on ethnic differences in SRH–mortality association in Estonia and more generally on socioeconomic inequalities in mortality in Eastern Europe. (Source: Medicina)
Source: Medicina - May 3, 2017 Category: Journals (General) Source Type: research
Infantile hemangioma: Predicting proliferation by infrared thermography
Conclusions IRT is a time and cost effective tool, and is easy to learn. The surface temperature of IH reflects its remaining growth potential and could be used in the outpatient setting for the evaluation and follow-up of IH. (Source: Medicina)
Source: Medicina - April 20, 2017 Category: Journals (General) Source Type: research
Maternal obesity and obstetric outcomes in a tertiary referral center
Conclusions Maternal obesity is significantly associated with an increased risk of gestational hypertension, preeclampsia, gestational diabetes, dystocia, labor induction, failed induction of labor, large-for-gestational-age newborns and cesarean delivery. (Source: Medicina)
Source: Medicina - April 19, 2017 Category: Journals (General) Source Type: research
Interaction of ethidium and tetraphenylphosphonium cations with Salmonella enterica cells
Conclusions Results of our experiments indicate that ionic strength of the incubation medium influence the selectivity, the medium temperature and the assay conditions impact the kinetics of efflux. The lower accumulated amount and the weaker fluorescence of Et+ registered in slightly acidic medium indicate that ΔΨ plays a role in the accumulation of this indicator cation. The bound amount of Et+ to the de-energized or permeabilized cells considerably varies depending on the conditions and methods of de-energization or permeabilization of cells. Tris/EDTA permeabilization of the cells does not inhibit the efflux. (Source: Medicina)
Source: Medicina - April 18, 2017 Category: Journals (General) Source Type: research
Plasticity of vagal afferent signaling in the gut
Publication date: Available online 10 April 2017 Source:Medicina Author(s): Gintautas Grabauskas, Chung Owyang Vagal sensory neurons mediate the vago-vagal reflex which, in turn, regulates a wide array of gastrointestinal functions including esophageal motility, gastric accommodation and pancreatic enzyme secretion. These neurons also transmit sensory information from the gut to the central nervous system, which then mediates the sensations of nausea, fullness and satiety. Recent research indicates that vagal afferent neurons process non-uniform properties and a significant degree of plasticity. These properties are im...
Source: Medicina - April 10, 2017 Category: Journals (General) Source Type: research
Hepcidin serum levels and resistance to recombinant human erythropoietin therapy in hemodialysis patients
Conclusions CRP, albumin, BMI, and hospitalization rate per year were found to be significant determinants of ERI in MHD patients. Inadequate dialysis was associated with higher epoetin requirements. There were no difference in patient mortality by ERI, but a significant difference in hospitalization rates and mean length of one hospitalization was revealed. A significant positive relation between hepcidin and ERI was revealed. ERI and ferritin were found to be significant determinants of hepcidin in MHD patients. Hepcidin was not related to mortality. (Source: Medicina)
Source: Medicina - March 31, 2017 Category: Journals (General) Source Type: research
Pathologic fracture of the thoracic spine in a male master ultra-marathoner due to the combination of a vertebral hemangioma and osteopenia
Publication date: Available online 27 March 2017 Source:Medicina Author(s): Beat Knechtle, Pantelis T. Nikolaidis, Bruno Lutz, Thomas Rosemann, Christian Bärlocher Vertebral hemangiomas are the most common benign vertebral neoplasms and are generally asymptomatic. In the present study, we report the case of a 52-year-old male master ultra-marathoner suffering from a pathologic fracture of the thoracic spine due to a vertebral hemangioma. A further examination in the athlete revealed an accompanying osteopenia, which was most likely due to a deficiency in both vitamin D and testosterone. The treatment of the fractur...
Source: Medicina - March 27, 2017 Category: Journals (General) Source Type: research
The comparison of knee osteoarthritis treatment with single-dose bone marrow-derived mononuclear cells vs. hyaluronic acid injections
Conclusions The intra-articular injection of bone marrow-derived mononuclear cells is a safe manipulation with no side effects during the 12-month period. This treatment provides statistically significant clinical improvement between the starting point and 1, 3, 6, and 12 months after. When compared to hyaluronic acid treatment, better pain relief in the long-term period of mononuclear cell group was observed. (Source: Medicina)
Source: Medicina - March 22, 2017 Category: Journals (General) Source Type: research
Left atrial mechanics in patients with acute STEMI and secondary mitral regurgitation: A prospective pilot CMR feature tracking study
Conclusions Conventional volumetric and functional LA parameters do not detect early changes in LA performance in patients with STEMI and secondary MR. In contrast, LA reservoir, passive and active strain are significantly higher in patients with MR. Only peak early negative strain rate substantially increases during secondary MR. LA deformation parameters derived from conventional cine images using CMR-FT technique are highly reproducible. (Source: Medicina)
Source: Medicina - March 2, 2017 Category: Journals (General) Source Type: research
VEGF-A, sVEGFR-1, and sVEGFR-2 in BCR-ABL negative myeloproliferative neoplasms
Conclusions The study showed an increased level of VEGF-A, which may indicate the intensity of neoangiogenesis in the bone marrow. Decreased sVEGFR-1 and sVEGFR-2 in the blood of patients with MPNs may reflect consumption of these soluble receptors. (Source: Medicina)
Source: Medicina - February 23, 2017 Category: Journals (General) Source Type: research
Assessment of coronary care management and hospital mortality from ST-segment elevation myocardial infarction in the Kazakhstan population: Data from 2012 to 2015
Conclusions The present study demonstrated that hospitalization delay in the treatment of STEMI patients in Kazakhstan population was without significant changes, meanwhile the number of patients perfused within 1h from hospitalization to PCI tended to increase during 2012–2015. The higher hospital mortality was associated with study year, female gender, older age, longer-time from hospitalization to PCI and shorter hospitalization. (Source: Medicina)
Source: Medicina - February 20, 2017 Category: Journals (General) Source Type: research
Evaluation of atrial fibrillation management and cardiovascular risk profile in atrial fibrillation patients: A cross-sectional survey
Conclusions Compliance with the treatment guidelines remains suboptimal and further patient education is needed. (Source: Medicina)
Source: Medicina - February 20, 2017 Category: Journals (General) Source Type: research
VEGF-A, sVEGFR-1 and sVEGFR-2 in BCR-ABL negative myeloproliferative neoplasms
Conclusions The study showed an increased level of VEGF-A, which may indicate the intensity of neoangiogenesis in the bone marrow. Decreased sVEGFR-1 and sVEGFR-2 in the blood of patients with MPNs may reflect consumption of these soluble receptors. (Source: Medicina)
Source: Medicina - February 2, 2017 Category: Journals (General) Source Type: research
Familial hematuria: A review
Publication date: Available online 31 January 2017 Source:Medicina Author(s): Pavlína Plevová, Josef Gut, Jan Janda The most frequent causes of familial glomerular hematuria is thin basement membrane nephropathy (TBMN) caused by germline COL4A3 or COL4A4 gene mutations. Less frequent but important cause with respect to morbidity is Alport syndrome caused by germline COL4A5 gene mutations. The features of Alport syndrome include hematuria, proteinuria and all males with X-linked disease and all individuals with recessive disease will develop end stage renal disease, usually at early youth. In X-linked Alport syndrome...
Source: Medicina - January 31, 2017 Category: Journals (General) Source Type: research
