Safety and efficacy of stereotactic aspiration with fibrinolysis for deep-seated spontaneous intracerebral hemorrhages: A single-center experience
Conclusions Stereotactic clot aspiration with subsequent fibrinolytic therapy is safe and feasible treatment procedure associated with significant hematoma resolution rates and acceptable patient outcomes. (Source: Medicina)
Source: Medicina - August 4, 2017 Category: General Medicine Source Type: research

Utilization of cardiovascular medicines and cardiovascular mortality in Lithuania, Sweden and Norway in 2003 –2012
Conclusion We confirmed the strong negative correlation between CV medicines utilization and CV mortality in all countries. The strong correlation was found between CV-SDR and nine factors, also between the use of CV medicines and nine factors. The impact of factors on the medicines induced decrease in CV-SDR showed the stronger influence in case of lower unemployment, higher alcohol consumption and higher amount of beds for hospitalization. (Source: Medicina)
Source: Medicina - August 1, 2017 Category: General Medicine Source Type: research

Factors influencing renal graft survival: 7-Year experience of a single center
Conclusions Donor factors, such as age, female gender, brain death of cerebrovascular cause and expanded criteria donor status had a significant negative impact on the renal graft function 1 year after transplantation. Recipients’ age, urinary tract infection and acute graft rejection episodes after transplantation were associated with a worse kidney function 1 year after transplantation. Lower 1-year graft survival was related to a delayed graft function (DGF) and a higher degree of glomerulosclerosis. (Source: Medicina)
Source: Medicina - July 29, 2017 Category: General Medicine Source Type: research

Prevalence of cardiovascular disease risk factors in Tallinn, Estonia
Conclusions The study established a high prevalence of cardiovascular disease risk factors in Estonian adults (20–65 years of age). Younger portion of the population and some extent ethnic considerations should be taken into account when designing future studies, health prevention activities and interventions. (Source: Medicina)
Source: Medicina - July 26, 2017 Category: General Medicine Source Type: research

Morphometric parameters of the optic disk in normal and glaucomatous eyes based on time-domain optical coherence tomography image analysis
Conclusions Informative results with regard to the size and shape due to various ocular characteristics between the healthy control group and patients suffering with primary open angle glaucoma were obtained. Both study groups were significant in size, which makes the findings interesting and important contribution in the field. (Source: Medicina)
Source: Medicina - July 20, 2017 Category: General Medicine Source Type: research

Mortality prediction in patients with acute kidney injury requiring renal replacement therapy after cardiac surgery
Conclusions Our study demonstrated that SOFA score estimation is the most accurate to predict the fatal outcome in patients with AKI requiring RRT after cardiac surgery. Lethal patient outcome is related to Glasgow coma score, mean arterial blood pressure, preoperative serum creatinine and postoperative platelet count. (Source: Medicina)
Source: Medicina - July 15, 2017 Category: General Medicine Source Type: research

Scaffold design for artificial tissue with bone marrow stem cells
Conclusions The obtained results suggest that electrospinning technology and femtosecond laser micro-structuring could be employed for the development of multi-layer scaffolds. Different biopolymers, such as PLA, fibrin, and collagen, could be used as appropriate environments for cell inhabitation and as an inner layer of the multi-layer scaffold. PI could be suitable as a barrier blocking cell migration from the scaffold. However, additional studies are needed to determine optimal parameters of inner and outer scaffold layers. (Source: Medicina)
Source: Medicina - July 14, 2017 Category: General Medicine Source Type: research

Use of interferon-gamma release assay and tuberculin skin test in diagnosing tuberculosis in Lithuanian adults: A comparative analysis
Conclusions The T SPOT TB showed greater accuracy in diagnosing TB than TST did. Positive T SPOT TB result but not the TST was more common in patients with diagnosed TB. (Source: Medicina)
Source: Medicina - July 4, 2017 Category: General Medicine Source Type: research

The influence of oxazaphosphorine agents on kidney function in rats
Conclusions CP caused more advanced kidney dysfunction and some indices suggested the development of prerenal acute kidney injury. In the CP-treated group some particularly marked urinary and plasma uric acid disturbances suggested compensation of increased oxidative stress as uric acid is considered to exert also antioxidant properties. (Source: Medicina)
Source: Medicina - July 3, 2017 Category: General Medicine Source Type: research

Periodontal status in 18-year-old Lithuanian adolescents: An epidemiological study
Conclusions The results of our study showed that the periodontal and oral hygiene status of 18-year-old Lithuanian population could be characterized as poor. In total, 77.1% of the study participants were found to have periodontal conditions such as gum bleeding, dental calculus, and shallow pockets. The anterior teeth of the mandible were most frequently affected. (Source: Medicina)
Source: Medicina - June 23, 2017 Category: General Medicine Source Type: research

Preoperative long-course chemoradiotherapy plus adjuvant chemotherapy versus short-course radiotherapy without adjuvant chemotherapy both with delayed surgery for stage II –III resectable rectal cancer: 5-Year survival data of a randomized controlled trial
Conclusions The 5-year DFS and OS were significantly better in the CRT than the SCRT group. For ITT population, OS was also significantly better after CRT versus SCRT. (Source: Medicina)
Source: Medicina - June 22, 2017 Category: General Medicine Source Type: research

Syphilitic coronary artery ostial stenosis resulting in acute myocardial infarction
We present the case of a 37-year-old male who was treated for an acute myocardial infarction due to bilateral coronary artery ostial stenosis secondary to syphilitic aortitis. According to the multidisciplinary decision, surgical revascularization (coronary artery bypass grafting, CABG) was performed. According to dermatologist recommendation, patient postoperative cardiovascular treatment was supplemented with intramuscular doses of benzathine penicillin recommended for tertiary syphilis. Further follow-up visits were also planned to detect possible changes of the aortic wall, dynamics of aortic regurgitation or potential...
Source: Medicina - June 21, 2017 Category: General Medicine Source Type: research

Potential to induce dentinal cracks during retreatment procedures of teeth treated with “Russian red”: An ex vivo study
Conclusions Retreatment methods had a damaging effect on the root dentin of teeth previously treated with resorcinol–formaldehyde resin. At magnification ×16, the efficacy of using the dye for the detection of cracks was higher than detection without the dye. (Source: Medicina)
Source: Medicina - June 8, 2017 Category: General Medicine Source Type: research

Alternans in atria: Mechanisms and clinical relevance
Publication date: Available online 7 June 2017 Source:Medicina Author(s): Giedrius Kanaporis, Lothar A. Blatter Atrial fibrillation is the most common sustained arrhythmia and its prevalence is rapidly rising with the aging of the population. Cardiac alternans, defined as cyclic beat-to-beat alternations in contraction force, action potential (AP) duration and intracellular Ca2+ release at constant stimulation rate, has been associated with the development of ventricular arrhythmias. Recent clinical data also provide strong evidence that alternans plays a central role in arrhythmogenesis in atria. The aim of this artic...
Source: Medicina - June 7, 2017 Category: General Medicine Source Type: research

A role of alpha-tocopherol and phylloquinone in the modulation of uterine contractility and reproductive function in mouse models
Conclusions Alpha-tocopherol and phylloquinone have been shown to directly modulate uterine contractility and reproductive function and may contribute to the management and treatment of reproductive disorders. (Source: Medicina)
Source: Medicina - May 31, 2017 Category: General Medicine Source Type: research