Effects of low-dose topiramate on language function in children with migraine.
CONCLUSION: No significant difference was found in the language-speaking ability between the patients; however, the number of vocabularies used decreased. Therefore, topiramate should be used cautiously for children with migraine.
PMID: 28861114 [PubMed] (Source: Korean Journal of Pediatrics)
Source: Korean Journal of Pediatrics - September 3, 2017 Category: Pediatrics Tags: Korean J Pediatr Source Type: research
A pediatric case of relapsed pulmonary alveolar proteinosis despite successful whole lung lavage.
Authors: Jin SY, Yun HR, Choi YJ, Park JD, Kim JT, Kang CH, Park YS, Choi YH, Kim WS, Suh DI
Abstract
Pulmonary alveolar proteinosis (PAP) is a rare disease in children characterized by intra-alveolar accumulation of surfactant proteins, which severely reduces gaseous exchange. Whole lung lavage (WLL) is the preferred technique for the treatment of severe PAP. Herein, we present a pediatric case of PAP treated with WLL. An 11-year-old boy was admitted with the chief complaint of a dry cough lasting 6 months. He developed symptoms of dyspnea on exertion and had difficulty in climbing stairs. He was ultimate...
Source: Korean Journal of Pediatrics - September 3, 2017 Category: Pediatrics Tags: Korean J Pediatr Source Type: research
Mechanism of resistance acquisition and treatment of macrolide-resistant Mycoplasma pneumoniae pneumonia in children.
Authors: Yang HJ, Song DJ, Shim JY
Abstract
Mycoplasma pneumoniae pneumonia (MPP) is one of the most common forms of community-acquired pneumonia in children and adolescents. Outbreaks of MPP occur in 3- to 7-year cycles worldwide; recent epidemics in Korea occurred in 2006-2007, 2011, and 2015-2016. Although MPP is known to be a mild, self-limiting disease with a good response to macrolides, it can also progress into a severe and fulminant disease. Notably, since 2000, the prevalence of macrolide-resistant MPP has rapidly increased, especially in Asian countries, recently reaching up to 80%-90%. Macrolide...
Source: Korean Journal of Pediatrics - July 12, 2017 Category: Pediatrics Tags: Korean J Pediatr Source Type: research
Individualized ibuprofen treatment using serial B-type natriuretic peptide measurement for symptomatic patent ductus arteriosus in very preterm infants.
CONCLUSION: Individualized BNP-guided pharmacological treatment may be used clinically to avoid unnecessary doses of cyclooxygenase inhibitors without increasing the ductal closure failure and the short-term morbidity related to sPDA.
PMID: 28690644 [PubMed - in process] (Source: Korean Journal of Pediatrics)
Source: Korean Journal of Pediatrics - July 12, 2017 Category: Pediatrics Tags: Korean J Pediatr Source Type: research
Neuroprotective effects of erythropoietin against hypoxic injury via modulation of the mitogen-activated protein kinase pathway and apoptosis.
CONCLUSION: Pretreatment with rHuEPO exerts neuroprotective effects against hypoxic injury reducing apoptosis by caspase-dependent mechanisms. Pathologic, persistent ERK activation after hypoxic injury may be attenuateed by pretreatment with EPO supporting that EPO may regulate apoptosis by affecting ERK pathways.
PMID: 28690645 [PubMed - in process] (Source: Korean Journal of Pediatrics)
Source: Korean Journal of Pediatrics - July 12, 2017 Category: Pediatrics Tags: Korean J Pediatr Source Type: research
Effects of lamotrigine on attention-deficit hyperactivity disorder in pediatric epilepsy patients.
CONCLUSION: The results from our study show that lamotrigine had a positive effect in pediatric epilepsy patients by reducing ADHD symptoms, preventing seizures, and normalizing EEG. However, further research is required to determine whether lamotrigine is efficacious against ADHD symptoms independent of its effects on epileptic seizures.
PMID: 28690646 [PubMed - in process] (Source: Korean Journal of Pediatrics)
Source: Korean Journal of Pediatrics - July 12, 2017 Category: Pediatrics Tags: Korean J Pediatr Source Type: research
The evolution of electrocardiographic changes in patients with Duchenne muscular dystrophies.
CONCLUSION: The prevalence of lead with fQRS representing regional wall motion abnormalities was higher in the young patients than in the young healthy controls, and this might be one of the first signs of myocardial change in the patients. Markers of depolarization and repolarization abnormalities were gradually prominent in the patients aged >10 years. Further studies are needed to confirm these findings.
PMID: 28690647 [PubMed - in process] (Source: Korean Journal of Pediatrics)
Source: Korean Journal of Pediatrics - July 12, 2017 Category: Pediatrics Tags: Korean J Pediatr Source Type: research
Prognostic factors and treatment of pediatric acute lymphoblastic leukemia.
Authors: Lee JW, Cho B
Abstract
The event-free survival (EFS) for pediatric acute lymphoblastic leukemia (ALL) has shown remarkable improvement in the past several decades. In Korea also, a recent study showed 10-year EFS of 78.5%. Much of the improved outcome for pediatric ALL stems from the accurate identification of prognostic factors, the designation of risk group based on these factors, and treatment of appropriate duration and intensity according to risk group, done within the setting of cooperative clinical trials. The schema of first-line therapy for ALL remains mostly unchanged, although many grou...
Source: Korean Journal of Pediatrics - June 9, 2017 Category: Pediatrics Tags: Korean J Pediatr Source Type: research
Healthcare access challenges facing six African refugee mothers in South Korea: a qualitative multiple-case study.
CONCLUSION: We identified barriers to maternal and child healthcare and coping strategies among African refugee mothers in Korea. Future research should assess refugees' health status and improve health access and literacy among refugee mothers.
PMID: 28592976 [PubMed - in process] (Source: Korean Journal of Pediatrics)
Source: Korean Journal of Pediatrics - June 9, 2017 Category: Pediatrics Tags: Korean J Pediatr Source Type: research
Clostridium difficile colonization and/or infection during infancy and the risk of childhood allergic diseases.
CONCLUSION: CDCI during infancy were associated with a higher risk of developing allergic diseases during early childhood. These results suggest that CDCI during infancy might reflect the reduced diversity of the intestinal microbiota, which is associated with an increased risk of allergic sensitization. To identify the underlying mechanism, further investigation and a larger cohort study will be needed.
PMID: 28592977 [PubMed - in process] (Source: Korean Journal of Pediatrics)
Source: Korean Journal of Pediatrics - June 9, 2017 Category: Pediatrics Tags: Korean J Pediatr Source Type: research
Prevalence and clinical manifestations of macrolide resistant Mycoplasma pneumoniae pneumonia in Korean children.
CONCLUSION: The macrolide resistant rate of M. pneumoniae is very high in children with M. pneumoniae pneumonia in Korea. The clinical manifestations of MRMP are similar to MSMP except for the defervescence period after administration of macrolide. Continuous monitoring of the occurrence and antimicrobial susceptibility of MRMP is required to control its spread and establish strategies for treating second-line antibiotic resistant M. pneumoniae infection.
PMID: 28592978 [PubMed - in process] (Source: Korean Journal of Pediatrics)
Source: Korean Journal of Pediatrics - June 9, 2017 Category: Pediatrics Tags: Korean J Pediatr Source Type: research
Sleep problems in children and adolescents at pediatric clinics.
CONCLUSION: Sleep problems are frequent among children in Korea. Children with snoring have an increased risk of sleepwalking, night terror, and bruxism. Primary clinicians should consider children's sleep habits to improve their health.
PMID: 28592979 [PubMed - in process] (Source: Korean Journal of Pediatrics)
Source: Korean Journal of Pediatrics - June 9, 2017 Category: Pediatrics Tags: Korean J Pediatr Source Type: research
IgE-mediated food allergies in children: prevalence, triggers, and management.
Authors: Lee S
Abstract
Food allergy (FA) is a serious health problem, and severe FA such as food-induced anaphylaxis can often be life threatening. The incidence of FA has been increasing especially in children. They usually develop early in life and affect up to 10% of children. The 2 most common food allergens worldwide are milk and eggs, while the third one varies depending on the countries: peanuts in the United States and Switzerland, wheat in Germany and Japan, tree nuts in Spain, sesame in Israel, and walnuts in Korea. These common food allergens are different and difficult to identify because of d...
Source: Korean Journal of Pediatrics - May 4, 2017 Category: Pediatrics Tags: Korean J Pediatr Source Type: research
Neonatal indirect hyperbilirubinemia and glucose-6-phosphate dehydrogenase deficiency.
CONCLUSION: G6PD deficiency is an important risk factor for severe NIH. In G6PD-deficent neonates, management of NIH should be hastened to avoid irreversible neurological complications.
PMID: 28461823 [PubMed - in process] (Source: Korean Journal of Pediatrics)
Source: Korean Journal of Pediatrics - May 4, 2017 Category: Pediatrics Tags: Korean J Pediatr Source Type: research
Clinical usefulness of serum procalcitonin level in distinguishing between Kawasaki disease and other infections in febrile children.
CONCLUSION: PCT levels may help to differentiate KD from bacterial infections. A combination of disease markers, including ESR, CRP, and PCT, may be useful for differentiating between KD and viral/bacterial infections.
PMID: 28461824 [PubMed - in process] (Source: Korean Journal of Pediatrics)
Source: Korean Journal of Pediatrics - May 4, 2017 Category: Pediatrics Tags: Korean J Pediatr Source Type: research
