Pharmacodynamic assessment of diuretic efficacy and braking in a furosemide continuous infusion model
ConclusionsThere was a strong relationship between urine volume and absolute urine electrolyte excretion. Urine volume was strongly correlated to uNa:uK, giving it potential as a spot indicator of urine production during diuresis. The decrease in uNa:uK over time during the infusion is consistent with mineralocorticoid modification of urinary electrolyte excretion, supporting renin–angiotensin–aldosterone activation as a cause of diuretic braking in this model. (Source: Journal of Veterinary Cardiology)
Source: Journal of Veterinary Cardiology - July 10, 2018 Category: Veterinary Research Source Type: research

Journal title page and editorial board
Publication date: April 2018Source: Journal of Veterinary Cardiology, Volume 20, Issue 2Author(s): (Source: Journal of Veterinary Cardiology)
Source: Journal of Veterinary Cardiology - July 10, 2018 Category: Veterinary Research Source Type: research

Tricuspid annular plane systolic excursion-to-aortic ratio provides a bodyweight-independent measure of right ventricular systolic function in dogs
ConclusionsThe ratios, TAPSE:Ao and TAPSE:Ao(adj), are a bodyweight-independent means of assessing right ventricular systolic function in dogs and for identifying severe PH in dogs with or without MMVD. (Source: Journal of Veterinary Cardiology)
Source: Journal of Veterinary Cardiology - July 10, 2018 Category: Veterinary Research Source Type: research

Polymerase chain reaction detection of Bartonella spp. in dogs from Spain with blood culture-negative infectious endocarditis
ConclusionsBartonella could be an important cause of blood culture-negative infectious endocarditis in dogs from Spain. The outcome for those dogs affected with Bartonella spp. was grave. Prompt empirical treatment with amoxicillin-clavulanate plus fluoroquinolones could be of value in cases of blood culture-negative endocarditis. (Source: Journal of Veterinary Cardiology)
Source: Journal of Veterinary Cardiology - July 10, 2018 Category: Veterinary Research Source Type: research

Diagnostic accuracy of plasma atrial natriuretic peptide concentrations in cats with and without cardiomyopathies
ConclusionsPlasma ANP concentrations were higher in cats with more advanced cardiomyopathy. Although assaying the ANP concentration alone may not help to diagnose cardiac disease, measuring provides additional information that is useful for assessing the severity of cardiomyopathies. (Source: Journal of Veterinary Cardiology)
Source: Journal of Veterinary Cardiology - July 10, 2018 Category: Veterinary Research Source Type: research

Low-energy ablation of anteroseptal accessory pathways in two dogs
In conclusion, anteroseptal APs can be effectively treated by low-energy radiofrequency catheter ablation with minimal and transient damage to the atrioventricular junction. (Source: Journal of Veterinary Cardiology)
Source: Journal of Veterinary Cardiology - July 10, 2018 Category: Veterinary Research Source Type: research

Plasma homocysteine concentrations in healthy horses and horses with atrial fibrillation
ConclusionsThis assay allows precise measurement of [HCY]p in horses. Unlike in people, [HCY]p is not increased in horses with AF and cannot predict AF recurrence. This might be due to differences in the underlying pathological mechanisms of AF development in people and horses. (Source: Journal of Veterinary Cardiology)
Source: Journal of Veterinary Cardiology - July 10, 2018 Category: Veterinary Research Source Type: research

Considerations for analysis of time-to-event outcomes subject to competing risks in veterinary clinical studies
This article provides an introductory overview and illustrates concepts with examples from veterinary trials and with example data sets. (Source: Journal of Veterinary Cardiology)
Source: Journal of Veterinary Cardiology - July 10, 2018 Category: Veterinary Research Source Type: research

Clinical and electrocardiographic presentations of transient trifascicular block in three cats
This report describes transient trifascicular block in three cats presented with lethargy and inappetence, and elevated cardiac troponin I concentrations.The electrocardiogram (ECG) of cat 1 showed a sinus rhythm with pronounced first-degree atrioventricular (AV) block, right bundle branch block, and left anterior fascicular block. The ECG of cat 2 showed truncular left bundle branch block alternating with left anterior fascicular block coupled with prolonged PR intervals, second-degree heart block, and paroxysmal third-degree AV block. The ECG of cat 3 showed first-degree AV block with concomitant right bundle branch bloc...
Source: Journal of Veterinary Cardiology - July 10, 2018 Category: Veterinary Research Source Type: research

Investigation of ventricular pre-excitation electrocardiographic pattern in two horses: clinical presentation and potential causes
Publication date: June 2018Source: Journal of Veterinary Cardiology, Volume 20, Issue 3Author(s): Judit Viu, Lara Armengou, Annelies Decloedt, Eduard Jose-CunillerasAbstractTwo horses referred to the Unitat Equina, Fundació Hospital Clínic Veterinari, Universitat Autònoma de Barcelona, for unrelated clinical problems, and with no previous history of cardiac disease exhibited an intermittent ventricular pre-excitation electrocardiographic pattern during hospitalization. Both animals showed decreased plasma total and ionized magnesium concentrations, but no other relevant electrolyte disturbances were detected. Altered in...
Source: Journal of Veterinary Cardiology - July 10, 2018 Category: Veterinary Research Source Type: research

Journal title page and editorial board
Publication date: June 2018Source: Journal of Veterinary Cardiology, Volume 20, Issue 3Author(s): (Source: Journal of Veterinary Cardiology)
Source: Journal of Veterinary Cardiology - July 10, 2018 Category: Veterinary Research Source Type: research

Transient myocardial thickening in a Bartonella henselae–positive cat
Publication date: June 2018Source: Journal of Veterinary Cardiology, Volume 20, Issue 3Author(s): J.L. Joseph, E.M. Oxford, R.A. SantilliAbstractA 3-year-old castrated male domestic shorthair presented to the Cornell University Hospital for Animals for acute onset respiratory distress. Thoracic radiographs, echocardiogram, and electrocardiogram (ECG) revealed left-sided congestive heart failure, myocardial thickening with left atrial dilation, and sinus rhythm conducted with a left bundle branch block, respectively. Cardiac troponin I was elevated and continued to increase over 36 h (1.9 ng/mL, 3.1 ng/mL, and 3.5 ng/mL...
Source: Journal of Veterinary Cardiology - July 10, 2018 Category: Veterinary Research Source Type: research

Prognostic value of mitral annular systolic plane excursion and tricuspid annular plane systolic excursion in cats with hypertrophic cardiomyopathy
ConclusionsLower MAPSE and TAPSE were not independently associated with outcomes on multivariable analysis. Cats with pleural effusion ± pulmonary oedema had lower TAPSE and MAPSE IVS than cats with pulmonary oedema, and MAPSE IVS was the only predictive factor associated with the development of pleural effusion in this population. (Source: Journal of Veterinary Cardiology)
Source: Journal of Veterinary Cardiology - July 10, 2018 Category: Veterinary Research Source Type: research

Evaluation of tricuspid annular plane systolic excursion measured by two-dimensional echocardiography in healthy dogs: repeatability, reference intervals, and comparison with M-mode assessment
ConclusionsTwo-dimensional echocardiography TAPSE appears well suited for clinical assessment of RV function. The TAPSE methods should not be used interchangeably. (Source: Journal of Veterinary Cardiology)
Source: Journal of Veterinary Cardiology - July 10, 2018 Category: Veterinary Research Source Type: research

Assessment of longitudinal systolic function using tissue motion annular displacement in healthy dogs
ConclusionsTissue motion annular displacement is a rapid and reproducible method for the assessment of left ventricle longitudinal function in healthy dogs. However, more studies are needed to validate the real clinical applicability of TMAD in animals with heart diseases. (Source: Journal of Veterinary Cardiology)
Source: Journal of Veterinary Cardiology - July 10, 2018 Category: Veterinary Research Source Type: research