Aortic dissection in four cats: clinicopathological correlations
We describe a series of 4 cats with AD of the ascending aorta and moderate aortic insufficiency. Three cats had an acute onset of clinical signs with pericardial effusion and cardiac tamponade, while one cat showed a chronic onset without pericardial effusion. Detailed gross and histopathological characterization is available for two cats, which revealed the typical features of AD. One cat also showed connective tissue abnormalities microscopically resembling Marfan-like syndrome. Concomitant detection of hypertrophic cardiomyopathy (HCM) in 2 cats represents a novel finding in the veterinary literature. Feline aortic diss...
Source: Journal of Veterinary Cardiology - September 28, 2019 Category: Veterinary Research Source Type: research

Plasma Growth Differentiation Factors 8 and 11 levels in cats with congestive heart failure secondary to hypertrophic cardiomyopathy
ConclusionsPlasma GDF11 was not different between cats with HCM/HOCM and cats with normal cardiac structure regardless of age. Plasma GDF8 was decreased in cats with CHF compared to cats with normal cardiac structure and cats with asymptomatic HCM/HOCM, suggesting a possible role in CHF development. (Source: Journal of Veterinary Cardiology)
Source: Journal of Veterinary Cardiology - September 3, 2019 Category: Veterinary Research Source Type: research

Dilatable Pulmonary Artery Banding for Ventricular Septal Defect: Surgical Technique and Case Report of 3 Cats
This report describes a surgical technique for placement of a dilatable pulmonary artery band, reviews guidelines for tightening the band, and reports the outcome of three cats undergoing the procedure. All three cats showed evidence of reduced hemodynamic load after PAB for a period of up to three years after PAB. (Source: Journal of Veterinary Cardiology)
Source: Journal of Veterinary Cardiology - August 28, 2019 Category: Veterinary Research Source Type: research

Journal title page and editorial board
Publication date: August 2019Source: Journal of Veterinary Cardiology, Volume 24Author(s): (Source: Journal of Veterinary Cardiology)
Source: Journal of Veterinary Cardiology - August 10, 2019 Category: Veterinary Research Source Type: research

Use of rivaroxaban for treatment of cranial vena cava syndrome secondary to transvenous pacemaker lead thrombosis in a dog
Publication date: Available online 25 July 2019Source: Journal of Veterinary CardiologyAuthor(s): B.L. Miranda, R. Walton, D.N. LeVine, A. Blong, W. Ware, J. WardAbstractA six-year-old Brussels griffon was presented for cervical swelling three months after implantation of a transvenous pacemaker. Transthoracic echocardiography demonstrated a thrombus associated with the pacemaker lead, partially obstructing right atrial inflow. The laboratory findings were consistent with protein-losing nephropathy. Initial medical therapy consisted of rivaroxaban (0.68 mg/kg PO q 24 hr), clopidogrel (2.5 mg/kg PO q 24 hr), and enalapr...
Source: Journal of Veterinary Cardiology - August 9, 2019 Category: Veterinary Research Source Type: research

Cor triatriatum sinister in a dog
This report describes the transthoracic and transesophageal echocardiographic features of a cor triatriatum sinister in an asymptomatic 6-year-old male French bulldog. Although cor triatriatum sinister represents a well-known and widely described cardiac malformation in humans, its description in the canine population is rare. In this clinical case, non-invasive echocardiographic techniques were helpful in visualizing and characterizing the lesion, allowing a valuable assessment of the malformation, and its hemodynamic consequences. (Source: Journal of Veterinary Cardiology)
Source: Journal of Veterinary Cardiology - July 27, 2019 Category: Veterinary Research Source Type: research

Use of rivaroxaban for treatment of cranial vena caval syndrome secondary to transvenous pacemaker lead thrombosis in a dog
Publication date: Available online 25 July 2019Source: Journal of Veterinary CardiologyAuthor(s): Becky Lozada Miranda, Rebecca Walton, Dana N. LeVine, April Blong, Wendy Ware, Jessica WardAbstractA six-year-old Brussels Griffon was presented for cervical swelling three months after implantation of a transvenous pacemaker. Transthoracic echocardiography demonstrated a thrombus associated with the pacemaker lead, partially obstructing right atrial inflow. Laboratory findings were consistent with protein-losing nephropathy. Initial medical therapy consisted of rivaroxaban (0.68 mg/kg PO q 24 hr), clopidogrel (2.5 mg/kg PO q ...
Source: Journal of Veterinary Cardiology - July 25, 2019 Category: Veterinary Research Source Type: research

Inotropic and Chronotropic Effects of Sotalol in Healthy Dogs
ConclusionsSotalol has a mild negative inotropic effect in healthy dogs based on standard echocardiographic measurements. There is also a negative chronotropic effect at higher heart rates based on 24-hour Holter monitoring. (Source: Journal of Veterinary Cardiology)
Source: Journal of Veterinary Cardiology - July 25, 2019 Category: Veterinary Research Source Type: research

Diagnostic value of the pulmonary vein-to-right pulmonary artery ratio in dogs with pulmonary hypertension of precapillary origin
ConclusionsResults of the present study suggest that PV/PA can be useful as an additional, non-invasive, and indirect variable to identify precapillary PH in dogs. (Source: Journal of Veterinary Cardiology)
Source: Journal of Veterinary Cardiology - July 4, 2019 Category: Veterinary Research Source Type: research

Pharmacokinetic evaluation of a sustained-release compounded procainamide preparation after 24-h (acute) administration in normal dogs
ConclusionsAdministration of sustained-release procainamide twice daily achieved targeted plasma concentrations in most dogs. Evaluation of serum trough concentrations should be considered owing to interanimal variability to confirm that serum concentrations are within the reported therapeutic range for an individual patient. (Source: Journal of Veterinary Cardiology)
Source: Journal of Veterinary Cardiology - July 3, 2019 Category: Veterinary Research Source Type: research

Valvular aortic stenosis in three cats
Publication date: Available online 28 June 2019Source: Journal of Veterinary CardiologyAuthor(s): Claire E. Watson, Jessie Rose Payne, Kieran BorgeatAbstractAortic stenosis affects 0.028% of cats in a shelter population, with valvular aortic stenosis compromising almost half of these cases. Of congenital heart diseases reported in cat, aortic stenosis is the second most common, affecting 17% of these cases. Existing literature on valvular aortic stenosis is scant and thus presentation and prognosis of affected animals is poorly understood. In this case series we describe three cats with confirmed valvular aortic stenosis. ...
Source: Journal of Veterinary Cardiology - June 28, 2019 Category: Veterinary Research Source Type: research

Assessment of left atrial volume in dogs: comparisons of two-dimensional and real-time three-dimensional echocardiography with ECG-gated multidetector computed tomography angiography
ConclusionsReal-time three-dimensional echocardiography is a non-invasive, accurate and feasible method with superior accuracy to 2D methods. (Source: Journal of Veterinary Cardiology)
Source: Journal of Veterinary Cardiology - June 21, 2019 Category: Veterinary Research Source Type: research

Percutaneous transcatheter closure of an aorto-cardiac fistula in a six-year-old Warmblood mare with atrial fibrillation
This report describes a rare case of an aorto-cardiac fistula in a six-year-old French Warmblood mare presented with atrial fibrillation, decreased performance, ventral oedema, bounding arterial pulsation and pathological jugular venous pulse. A 2.7 cm diameter fistula connected the right aortic sinus of Valsalva to the right atrium. Atrial fibrillation was likely due to volume overload of the right heart due to left-to-right shunting. The horse was treated by percutaneous transcatheter closure of the fistula delivered under general anaesthesia using a transarterial approach. The operation was initially successful and clin...
Source: Journal of Veterinary Cardiology - June 21, 2019 Category: Veterinary Research Source Type: research

Diagnostic value of the pulmonary vein to right pulmonary artery ratio in dogs with pulmonary hypertension of pre-capillary origin
ConclusionsResults of the present study suggest that PV/PA can be useful as an additional, non-invasive, and indirect variable to identify pre-capillary PH in dogs. (Source: Journal of Veterinary Cardiology)
Source: Journal of Veterinary Cardiology - June 20, 2019 Category: Veterinary Research Source Type: research

Pharmacokinetic Evaluation of a Sustained-Release Compounded Procainamide Preparation Following 24-hour (Acute) Administration in Normal Dogs
ConclusionsTwice-daily administration of sustained-release procainamide achieved targeted plasma concentrations in most dogs. Evaluation of serum trough concentrations should be considered due to inter-animal variability to confirm that serum concentrations are within the reported therapeutic range for an individual patient. (Source: Journal of Veterinary Cardiology)
Source: Journal of Veterinary Cardiology - June 19, 2019 Category: Veterinary Research Source Type: research