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Anatomical and molecular studies of cytochrome P450 family CYP7A1 gene polymorphism and its association with gallstone in north Indian population
In this study, we have mainly focused on the molecular and biochemical aspects to know the cause of gall stone diseases in human. To know about these problems, there may be necessitating initiating interest in researchers of this field and to set up easily available tools and techniques. The screening of polymorphism with molecular approaches of P450 super family CYP7A1 gene was performed to explore its relation with gallstone diseases.MethodsTotal 300 samples (150 patients and 150 controls) were analyzed for the study. The polymorphisms were analyzed by PCR followed by RFLP with BsaI restriction enzyme. The lipid profile ...
Source: Journal of the Anatomical Society of India - July 10, 2018 Category: Anatomy Source Type: research

A morphometric study of human middle ear ossicles in cadaveric temporal bones of Indian population and a comparative analysis
DiscussionMorphometric data obtained in the present study can be useful for the reconstructive procedures. Preoperative radiological assessment is advised for these small bones. The present study also emphasizes on the future directions where in reconstructive procedures can be improved with the artistic renderings of the blueprints provided, for new prosthetic designs which can be manufactured by using Teflon materials. (Source: Journal of the Anatomical Society of India)
Source: Journal of the Anatomical Society of India - July 10, 2018 Category: Anatomy Source Type: research

Proximal attachment of long head of biceps brachii to the bicipital tubercle of scapula and its functional significance
ConclusionThe efficiency of action of LHB is enhanced by its getting a firm attachment to the bicipital tubercle (BT). Thus in man the origin of the tendon of LHB has shifted from only the SGT to SGT plus labrum, and further has got an additional attachment to BT. This attachment to the BT seems to have been overlooked and demands its inclusion in all the future studies. (Source: Journal of the Anatomical Society of India)
Source: Journal of the Anatomical Society of India - July 10, 2018 Category: Anatomy Source Type: research

Comparing safety margin of innervation points of the subscapular nerves from the base and tip of the coracoid process
DiscussionGreater margin of safety for upper and lower subscapular nerves was observed with the arm in neutral position in comparison to 30° abduction with external rotation position and base of coracoid could be more dependable landmark than its tip. (Source: Journal of the Anatomical Society of India)
Source: Journal of the Anatomical Society of India - July 10, 2018 Category: Anatomy Source Type: research

Role of folic acid supplementation and/ or its absence during pregnancy on implantation of embryos – An experimental study of Wistar rats
DiscussionFA is essential in successful implantation by providing favorable receptive environment to receive the implantation-competent blastocyst for a successful pregnancy. (Source: Journal of the Anatomical Society of India)
Source: Journal of the Anatomical Society of India - July 10, 2018 Category: Anatomy Source Type: research

Gestational diabetes reduced sertoli cells in 12 weeks age rat offsprings testis
This study was done to evaluate the effect of induced gestational diabetes on seminiferous tubule of 12 weeks age offspring rats.Methods10 Wistar rats' dams were randomly allocated to control and diabetic groups. Streptozotocin was used to induce diabetes in female rats. Dams in diabetic group received 40 mg/kg/BW of streptozotocin at the first day of gestation and control group animals received an equivalent volume of normal saline by intraperitoneally. Six offspring of each group were randomly selected on day 84 postnatal. Five micrometer sections were taken from testes, stained with hematoxylin and eosin. Photograp...
Source: Journal of the Anatomical Society of India - July 10, 2018 Category: Anatomy Source Type: research

The articular surfaces of the proximal segment of ulna: Morphometry and morphomechanics based on digital image analysis and concepts of fractal geometry
DiscussionA precise conclusion was reached in relation to morphometry, volumetry and the pertinent biomechanics of the proximal segment of the ulna. Key findings are of value to biomedical engineers, medical professionals including orthopaedic surgeons and rheumatologists, evolutionary biologist, and physical anthropologist. Data from this study can be used to (reverse) engineer the perfect implant for the elbow joint. (Source: Journal of the Anatomical Society of India)
Source: Journal of the Anatomical Society of India - July 10, 2018 Category: Anatomy Source Type: research

Anatomical variations of the formation of human sural nerve in stillborns
This study was performed to ensure an anatomical and morphometrical description of the sural nerve and its components in 18 embalmed stillborns. Due to its great importance in neurosurgery and plastic surgery, the formation type, course and formation level of the sural nerve have been studied on different races and age groups since the beginning of the last century. (Source: Journal of the Anatomical Society of India)
Source: Journal of the Anatomical Society of India - July 10, 2018 Category: Anatomy Source Type: research

Ossified ligaments in relation to foramina and bony landmarks of the middle cranial fossa
DiscussionPresence of ossified MCF ligaments cannot be overlooked in patients with symptoms arising from compression of neurovascular structures and those undergoing skull-base neurosurgery, necessitating pre-surgical screening for presence of calcified ligaments in close proximity to vital structures − a scenario that may influence surgical outcome. (Source: Journal of the Anatomical Society of India)
Source: Journal of the Anatomical Society of India - July 10, 2018 Category: Anatomy Source Type: research

Surgical anatomy of the vasculobiliary apparatus at the hepatic hilum as applied to liver transplantations and major liver resections
DiscussionIn the present study, the vasculobiliary anatomies of liver were highly complex with the existence of many anatomic variations. The increasing complexity of hepatic surgical procedures necessitates appropriate knowledge of these anatomic variations. (Source: Journal of the Anatomical Society of India)
Source: Journal of the Anatomical Society of India - July 10, 2018 Category: Anatomy Source Type: research

Myocardial bridging ‘a double-edged sword’: Analysis and significance
The objectives under study were to validate the prevalence and segments of coronaries with myocardial bridging, length and diameter of bridging segments and cardiac dominance patterns among a west coastal population of Kerala and Karnataka, India from coronary angiogram reports. The co-relation of bridged segments and cardiac dominance patterns in diseased and non-diseased coronary arteries were assessed to find out the significance of both in CAD.Materials and MethodsThe angiograms were obtained from K.S Hegde Medical Academy and Hospital, Karnataka after procuring the ethical clearance. 1000 cases with clinical symptoms,...
Source: Journal of the Anatomical Society of India - July 10, 2018 Category: Anatomy Source Type: research

Deplastination: Making plastinates histo-pathologically relevant
In this study, a slice of liver tissue was split into two parts. The first half was processed, sectioned and stained with routine H&E staining while the other half was plastinated with S10 plastination technique and was deplastinated after 3 months using sodium methoxide as the deplastinating agent. It was latter stained with routine H&E. The slides were assessed qualitatively on parameters like tissue and cell identification, staining property, preservation of tissue architecture, visualisation of intracellular structures like nuclei, nucleoli, fat goblets etc. and presence of artefacts due to the process.ResultsIdentific...
Source: Journal of the Anatomical Society of India - July 10, 2018 Category: Anatomy Source Type: research

Anatomic variations in the course of the hypoglossal nerve: A case report
Publication date: June 2018Source: Journal of the Anatomical Society of India, Volume 67, Issue 1Author(s): Gunjan Agrawal, Ashutosh Gupta, Vivek Chaudhary, Fiza QuerishiAbstractTo achieve a successful surgical anatomy a detailed knowledge of regional anatomy and anatomical variations is an important fundamental. The extra cranial hypoglossal nerve has a well described course as it traverses the neck, and is frequently identified during neck dissection. This serves a guide to the surgeon of such atypical variations in anatomy to avoid injury to important structures during dissection. We are presenting a case report which d...
Source: Journal of the Anatomical Society of India - July 10, 2018 Category: Anatomy Source Type: research

The Incidence of Civinini’s Bar in Adult Anatolian Dry Skulls: An Anatomical Study
DiscussionComplete or incomplete ossification of Civinini’s ligament have significant relation with blockage and entrapment of important neurovascular structures. A thorough knowledge of the anatomy and incidence of Civinini’s bar and related clinical situations could be important for radiologists, neurosurgeons, maxillofacial surgeons, anaesthetists, anatomists and anthropologists. (Source: Journal of the Anatomical Society of India)
Source: Journal of the Anatomical Society of India - July 10, 2018 Category: Anatomy Source Type: research

Algorithmic interpretation of head and neck computerized tomography (CT) images
Discussion.This structured comprehensive algorithm for the interpretation of head and neck CT scans is an effective and reliable reference tool that may enhance and refine ORL HNS resident training and knowledge. (Source: Journal of the Anatomical Society of India)
Source: Journal of the Anatomical Society of India - July 5, 2018 Category: Anatomy Source Type: research