Monitoring and Alleviation of Symptom Occurrence and Severity Among Thai Children and Adolescents During Cancer Treatments
Conclusions: Monitoring of multiple symptoms with the TRSC-C and parental symptom alleviation helped children. Clinical Implications: Thai parents/patients need and accept assistance in monitoring/managing side effects of pediatric cancer therapy. (Source: Journal of Pediatric Oncology Nursing)
Source: Journal of Pediatric Oncology Nursing - October 13, 2015 Category: Nursing Authors: Williams, P. D., Piamjariyakul, U., Shanberg, R., Williams, A. R. Tags: Research Source Type: research

Perceived Alienation of, and Social Support for, Siblings of Children With Cancer
This descriptive study was performed to identify the relationships among alienation, general social support, and nurses’ support for the siblings of children with cancer. The participants were 84 siblings of children with cancer. Alienation was measured by the revised version of Dean’s Alienation Scale, and general social support was quantified by the revised version of Dubow and Ullman’s Social Support Appraisal Scale. For nurses’ support, Murray’s Nurse–Sibling Social Support Questionnaire was used. Data were collected from July 2011 to December 2011. The participants’ alienation...
Source: Journal of Pediatric Oncology Nursing - October 13, 2015 Category: Nursing Authors: Yu, J., Bang, K.-S. Tags: Research Source Type: research

Reduction of Secondhand Smoke Exposure in the Cars of Children With Cancer
This study examined whether an intervention designed to reduce secondhand smoke exposure (SHSe) among children being treated for cancer had effects in the specific setting of a motor vehicle. The parents or guardians (n = 71) of children being treated for cancer were randomized to either a behavioral secondhand smoke (SHS) reduction program or a standard care control group. Parental reports of SHSe were collected over the course of 12 months. Younger children were exposed at baseline more than their older counterparts. The greatest initial declines in car exposure were observed among children ≤5 years old in the interve...
Source: Journal of Pediatric Oncology Nursing - October 13, 2015 Category: Nursing Authors: Peck, K. R., Tyc, V. L., Huang, Q., Zhang, H. Tags: Original Manuscripts Source Type: research

Implementing a Daily Maintenance Care Bundle to Prevent Central Line-Associated Bloodstream Infections in Pediatric Oncology Patients
Eliminating central line–associated bloodstream infection (CLABSI) is a national priority. Central venous catheter (CVC) care bundles are composed of a series of interventions that, when used together, are effective in preventing CLABSI. A CVC daily maintenance care bundle includes procedural guidelines for hygiene, dressing changes, and access as well as specific timeframes. Failure to complete one of the components of the care bundle predisposes the patient to a bloodstream infection. A nurse-led multidisciplinary team implemented and, for six months, sustained a daily maintenance care bundle for pediatric oncology...
Source: Journal of Pediatric Oncology Nursing - October 13, 2015 Category: Nursing Authors: Duffy, E. A., Rodgers, C. C., Shever, L. L., Hockenberry, M. J. Tags: Original Manuscripts Source Type: research

Health-Related Quality of Life of Adolescent and Young Adult Survivors of Central Nervous System Tumors: Identifying Domains From a Survivor Perspective
This article uses qualitative methods to describe the domains of health-related quality of life (HRQoL) that adolescent and young adult (AYA) survivors of central nervous system (CNS) tumors identify as important. Survivors clearly attributed aspects of their current HRQoL to their disease or its treatment. We identified 7 key domains of AYA CNS tumor survivorship: physical health, social well-being, mental health, cognitive functioning, health behaviors, sexual and reproductive health, and support systems. Although most aspects of HRQoL that survivors discussed represented new challenges, there were several areas where su...
Source: Journal of Pediatric Oncology Nursing - October 13, 2015 Category: Nursing Authors: Kuhlthau, K., Luff, D., Delahaye, J., Wong, A., Yock, T., Huang, M., Park, E. R. Tags: Original Manuscripts Source Type: research

Cancer-Related Pain and Pain Management: Sources, Prevalence, and the Experiences of Children and Parents
Advances in treatment mean children are increasingly cared for by their parents at home, leading to a shift in responsibility from health care professionals to parents. Little is known about parents’ pain management experiences and the etiology of pain experienced by children with cancer especially when at home. A rapid review of the literature was undertaken investigating children’s cancer-related pain, with emphasis on the management of pain outside the health care setting. Electronic databases were searched and a quality assessment was conducted. Forty-two articles were included. Despite advances in pain man...
Source: Journal of Pediatric Oncology Nursing - October 13, 2015 Category: Nursing Authors: Twycross, A., Parker, R., Williams, A., Gibson, F. Tags: Original Manuscripts Source Type: research

Designing a Metasynthesis Study in Pediatric Oncology Nursing Research
The synthesis of qualitative evidence is called metasynthesis. The term metasynthesis describes both a group of methods used to integrate the findings of individual qualitative research studies and the end product of a metasynthesis research project. In this article, pediatric oncology nurses are encouraged to use metasynthesis research to facilitate the integration of the existing body of qualitative pediatric oncology nursing research into practice. For pediatric oncology nurses to be successful in metasynthesis research, they require practical guidance in navigating the terminology and methodology of this evolving resea...
Source: Journal of Pediatric Oncology Nursing - October 13, 2015 Category: Nursing Authors: Sigurdson, C., Woodgate, R. Tags: Review Source Type: research

APHON/ASPHO Policy Statement for the Transition of Patients With Sickle Cell Disease From Pediatric to Adult Health Care
Summary: With advances in medical care, the majority of children with sickle cell disease are surviving to adulthood. Patients, families, and providers now face the need for this growing population to move from pediatric- to adult-focused care. In order to facilitate a successful transfer to adult health care, and prepare young adults for greater independence, it is recommended that all pediatric patients with sickle cell disease receive transition preparation. Association Position: As the professional voice of pediatric hematology/oncology healthcare practice, the Association of Pediatric Hematology/Oncology Nurses (APHO...
Source: Journal of Pediatric Oncology Nursing - October 13, 2015 Category: Nursing Authors: Bryant, R., Porter, J. S., Sobota, A. Tags: Policy Statement Source Type: research

Evaluation of Physician and Nurse Dyad Training Procedures to Deliver a Palliative and End-of-Life Communication Intervention to Parents of Children with a Brain Tumor
We describe evaluation of training procedures used to prepare MD/RN dyads to deliver an intervention entitled: Communication Plan: Early Through End of Life (COMPLETE) intervention. Our training was delivered to 5 pediatric neuro-oncologists and 8 pediatric nurses by a team of expert consultants (i.e., in medical ethics, communication, and PC/EOL) and parent advisors. Although half of the group received training in a 1-day program and half in a 2-day program, content for all participants included 4 modules: family assessment, goal-directed treatment planning, anticipatory guidance, and staff communication and follow-up. Ev...
Source: Journal of Pediatric Oncology Nursing - August 10, 2015 Category: Nursing Authors: Hendricks-Ferguson, V. L., Kane, J. R., Pradhan, K. R., Shih, C.-S., Gauvain, K. M., Baker, J. N., Haase, J. E. Tags: Research Source Type: research

Health-Related Quality of Life among Children and Adolescents during Hematopoietic Stem Cell Transplant Recovery
Health-related quality of life (HRQoL) has been noted to fluctuate among children during hematopoietic stem cell transplant (HSCT) recovery; however, the specific timing and associations of these changes are poorly understood. This repeated-measures study aimed to describe HRQoL changes among children and adolescents during the first 6 months of HSCT recovery and estimate the associations of demographic factors, diagnosis, transplant information, and symptoms with HRQoL. Twenty-three children and adolescents who received an allogeneic HSCT were recruited from a pediatric teaching institution in the southern United States. ...
Source: Journal of Pediatric Oncology Nursing - August 10, 2015 Category: Nursing Authors: Rodgers, C., Wills-Bagnato, P., Sloane, R., Hockenberry, M. Tags: Research Source Type: research

Pregnancy in a Patient With a Malignant Brain Tumor Taking Temozolomide: Case Report and Review of the Literature
We report the case of a 19-year-old woman with anaplastic oligodendroglioma (high-grade glioma) who became pregnant during maintenance chemotherapy consisting of TMZ 200 mg/m2 administered 5 days monthly. The TMZ was immediately discontinued after she developed a positive pregnancy test. She delivered a full-term healthy baby boy with no prenatal or perinatal complications. Adolescents and young adults with brain tumors are often sexually active and should receive intensive and repeated anticipatory guidance regarding contraception while receiving chemotherapy. Pediatric oncology nurses are in a unique position to provide ...
Source: Journal of Pediatric Oncology Nursing - August 10, 2015 Category: Nursing Authors: Evans, A. C., Nelson, M. B., Dhall, G. Tags: Case Studies Source Type: research

Evaluation of Biomarkers of Oxidative Stress and Apoptosis in Patients With Severe Methotrexate Neurotoxicity: A Case Series
This article reports clinical presentations of 3 patients with severe MTX toxicity as well as levels of oxidative stress and apoptosis biomarkers in cerebrospinal fluid (CSF). Oxidative stress was measured by oxidized phosphatidylcholine (PC), oxidized phosphatidylinositol (PI), and F2 isoprostanes; apoptosis was measured by caspase 3/7 activity. Most consistent biomarker changes in all 3 cases were increases in caspase 3/7 and F2 isoprostanes prior to acute toxicity while increases in oxidized phospholipids occurred slightly later. Progressive increases in F2 isoprostanes and caspase 3/7 activity prior to and/or during ac...
Source: Journal of Pediatric Oncology Nursing - August 10, 2015 Category: Nursing Authors: Taylor, O. A., Hockenberry, M. J., McCarthy, K., Gundy, P., Montgomery, D., Ross, A., Scheurer, M. E., Moore, I. M. Tags: Case Studies Source Type: research

Chronic Sorrow in Mothers of Children With Cancer
This study aimed to investigate chronic sorrow in mothers of children with cancer in selected hospitals in Tehran, Iran. It also sought to clarify the relationships between chronic sorrow and some demographic characteristics. In this descriptive, cross-sectional study, 264 mothers attending 3 pediatric teaching hospitals in Tehran were selected using convenience sampling. The subjects completed a demographic questionnaire and Kendall Chronic Sorrow Questionnaire (Persian version). Data were analyzed with descriptive and inferential (Mann-Whitney and Kruskal-Wallis tests) statistics in SPSS 16.0. The mean score on the Kenda...
Source: Journal of Pediatric Oncology Nursing - August 10, 2015 Category: Nursing Authors: Nikfarid, L., Rassouli, M., Borimnejad, L., Alavimajd, H. Tags: Original Manuscripts Source Type: research

The Mediating Role of Resilience on Quality of Life and Cancer Symptom Distress in Adolescent Patients With Cancer
The objective of this study was to describe cancer symptom distress, QoL, and resilience in adolescents with cancer and to determine whether resilience is a mediating variable. Forty adolescent cancer patients were recruited, and data were collected via a demographic questionnaire, the Cancer Symptom Distress Scale, the Resilience Scale, and the Minneapolis-Manchester Quality of Life Scale. Pearson’s correlation, multiple regressions, and the Sobel test were conducted. Both resilience and cancer symptom distress were regressed against QoL, accounting for 62.1% of observed variation in QoL scores. The bootstrap result...
Source: Journal of Pediatric Oncology Nursing - August 10, 2015 Category: Nursing Authors: Wu, W.-W., Tsai, S.-Y., Liang, S.-Y., Liu, C.-Y., Jou, S.-T., Berry, D. L. Tags: Original Manuscripts Source Type: research

The Effect of Perceived Parental Rearing Behaviors on Health-Related Quality of Life in Adolescents with Leukemia
As the prognosis of childhood leukemia has dramatically improved, clinical interest has been growing in health-related quality of life in adolescents with leukemia. An important factor in adolescent quality of life is their perception of parental rearing behavior. The aim of this study was to explore how perceived parental rearing behaviors related to the quality of life of adolescents with leukemia. A descriptive, exploratory study was conducted among 106 adolescents with leukemia using the Recalled Parental Rearing Behavior and the Minneapolis-Manchester Quality of Life scales. Data were examined using descriptive, corre...
Source: Journal of Pediatric Oncology Nursing - August 10, 2015 Category: Nursing Authors: Kim, D. H., Chung, N.-G., Lee, S. Tags: Original Manuscripts Source Type: research