Small-Cell Lung Cancer: New Directions for Systemic Therapy [COMMENTARIES]
(Source: Journal of Oncology Practice)
Source: Journal of Oncology Practice - February 11, 2016 Category: Cancer & Oncology Authors: Ramalingam, S. S. Tags: Radiation, Chemotherapy, Combined Modality COMMENTARIES Source Type: research

Multimodality Therapy for Limited-Stage Small-Cell Lung Cancer [Clinical Reviews]
Limited-stage small-cell lung cancer (SCLC) occurs in only one third of patients with SCLC, but it is potentially curable. Combined-modality therapy (chemotherapy and radiotherapy) has long been the mainstay of therapy for this condition, but more recent data suggest a role for surgery in early-stage disease. Prophylactic cranial irradiation seems to improve outcomes in patients who have responded to initial therapy. This review addresses the practical aspects of staging and treatment of patients with limited-stage SCLC. (Source: Journal of Oncology Practice)
Source: Journal of Oncology Practice - February 11, 2016 Category: Cancer & Oncology Authors: Almquist, D., Mosalpuria, K., Ganti, A. K. Tags: Small Cell, Diagnosis & Staging, Surgery, Radiation, Chemotherapy, Combined Modality Clinical Reviews Source Type: research

Immune Checkpoint Inhibition: A New Era in Lymphoma Treatment [COMMENTARIES]
(Source: Journal of Oncology Practice)
Source: Journal of Oncology Practice - February 11, 2016 Category: Cancer & Oncology Authors: Connors, J. M. Tags: Chemotherapy, Biologic Therapy, Biology & Immunology COMMENTARIES Source Type: research

Targeting Programmed Death 1/Programmed Death Ligand 1 in Lymphoma: A Game Changer [COMMENTARIES]
(Source: Journal of Oncology Practice)
Source: Journal of Oncology Practice - February 11, 2016 Category: Cancer & Oncology Authors: Younes, A. Tags: General public, Biologic Therapy, Biology & Immunology COMMENTARIES Source Type: research

Where Do Programmed Death-1 Inhibitors Fit in the Management of Malignant Lymphoma? [Clinical Reviews]
Tumor-specific cytotoxic T cells have the capacity to target and eradicate malignant B cells in patients with Hodgkin and non-Hodgkin lymphoma; however, multiple mechanisms, including regulatory T cells, immunosuppressive ligands, and immune exhaustion, suppress an effective antitumor immune response. One mechanism that is used by malignant cells to inhibit the immune response is overexpression of programmed death ligand 1 or 2 (PD-L1 or PD-L2) on the cancer cell surface. These ligands interact with the programmed death-1 (PD-1) receptor expressed on intratumoral T cells and provide an inhibitory signal, thereby suppressin...
Source: Journal of Oncology Practice - February 11, 2016 Category: Cancer & Oncology Authors: Ansell, S. M. Tags: Biologic Therapy, Biology & Immunology, Hematology Clinical Reviews Source Type: research

Demographics of the US Oncology Workforce [Practice Dashboard]
(Source: Journal of Oncology Practice)
Source: Journal of Oncology Practice - February 11, 2016 Category: Cancer & Oncology Authors: Towle, E. Tags: Practice Dashboard Source Type: research

Reduction of Inappropriate Prophylactic Pegylated Granulocyte Colony-Stimulating Factor Use for Patients With Non-Small-Cell Lung Cancer Who Receive Chemotherapy: An ASCO Quality Training Program Project of the Cleveland Clinic Taussig Cancer Institute [Quality in Action]
Conclusion: pGCSF was excessively prescribed for patients with NSCLC. Factors contributing to inappropriate use included provider lack of familiarity with guidelines and knowledge with regard to the risk of neutropenic fever for individual chemotherapy regimens, and electronic medical record chemotherapy templates that contain standing GCSF orders. Interventions to address these gaps quickly produced improved compliance with guidelines and led to significant cost savings. (Source: Journal of Oncology Practice)
Source: Journal of Oncology Practice - January 12, 2016 Category: Cancer & Oncology Authors: Martin Goodman, L., Moeller, M. B., Azzouqa, A.-G., Guthrie, A. E., Dalby, C. K., Earl, M. A., Cheng, C., Pennell, N. A., Shapiro, M., Velcheti, V., Stevenson, J. P. Tags: Clinical guidelines, Complications of cancer and cancer treatment, Quality, Patient safety, Quality of care, Quality in Action, Quality of Care, Cost of Cancer Care, Growth Factors, Febrile Neutropenia, Adult Medical Oncology, Chemotherapy Source Type: research

Erratum [Erratum]
(Source: Journal of Oncology Practice)
Source: Journal of Oncology Practice - January 12, 2016 Category: Cancer & Oncology Tags: Erratum Source Type: research

Delivering Patient Value by Using Process Improvement Tools to Decrease Patient Wait Time in an Outpatient Oncology Infusion Unit [Quality in Action]
Conclusion: By using the systematic PDCA tool, the team was able to identify opportunities to reduce waste in the system and streamline patient care. The results demonstrated a significant improvement in reducing patient wait time from arrival to premedication start time and increasing percentage of total value added during a patient's treatment cycle. (Source: Journal of Oncology Practice)
Source: Journal of Oncology Practice - January 12, 2016 Category: Cancer & Oncology Authors: Gjolaj, L. N., Campos, G. G., Olier-Pino, A. I., Fernandez, G. L. Tags: Training, Quality, Quality in Action, Practice Administration, Quality of Care, Efficiency of Care Source Type: research

Kikuchis Disease Masquerading As Refractory Lymphoma [Case Report]
(Source: Journal of Oncology Practice)
Source: Journal of Oncology Practice - January 12, 2016 Category: Cancer & Oncology Authors: Kallam, A., Bierman, P. J., Bociek, R. G. Tags: Case Report Source Type: research

Systemic Therapy for Stage IV Non-Small-Cell Lung Cancer: American Society of Clinical Oncology Clinical Practice Guideline Update [Guideline Summaries]
(Source: Journal of Oncology Practice)
Source: Journal of Oncology Practice - January 12, 2016 Category: Cancer & Oncology Authors: Masters, G. A., Johnson, D. H., Temin, S. Tags: Clinical guidelines, Management and treatment, ASCO Guidelines, Chemotherapy, Combined Modality, Pathology Guideline Summaries Source Type: research

Transition of Care for Inpatient Hematology Patients Receiving Chemotherapy: Development of Hospital Discharge Huddle Process and Effects of Implementation [Quality in Action]
Conclusion: There was significant decrease in preventable errors demonstrated after implementation of our care model. Developing a systematic approach to hospital discharges can lead to improvements and serve a model for other inpatient wards. (Source: Journal of Oncology Practice)
Source: Journal of Oncology Practice - January 12, 2016 Category: Cancer & Oncology Authors: Warsame, R., Kasi, P. M., Villasboas-Bisneto, J. C., Gallenberg, D., Wolf, R., Ward, J., Matt-Hensrud, N., Grethen, K., Colborn, L., Zeldenrust, S., Lacy, M. Q., Thompson, C. A. Tags: Patient safety, Quality in Action Source Type: research

Antiemetics: American Society of Clinical Oncology Focused Guideline Update [Guideline Summaries]
(Source: Journal of Oncology Practice)
Source: Journal of Oncology Practice - January 12, 2016 Category: Cancer & Oncology Authors: Hesketh, P. J., Bohlke, K., Kris, M. G. Tags: Clinical guidelines, Complications of cancer and cancer treatment, Treatment related issues, Palliative care, Quality of care, Emesis, ASCO Guidelines Guideline Summaries Source Type: research

Reducing Oncology Unit Central Line-Associated Bloodstream Infections: Initial Results of a Simulation-Based Educational Intervention [Quality in Action]
Conclusion: A targeted educational intervention using a simulated central line care model improved competence in central line care and resulted in decreased CLABSI rates for inpatient oncology patients. (Source: Journal of Oncology Practice)
Source: Journal of Oncology Practice - January 12, 2016 Category: Cancer & Oncology Authors: Page, J., Tremblay, M., Nicholas, C., James, T. A. Tags: Quality, Patient safety, Quality of care, Quality in Action, Caregiver, Outcomes Research, Quality of Care Source Type: research

Treatment of Small-Cell Lung Cancer: American Society of Clinical Oncology Endorsement of the American College of Chest Physicians Guideline [Guideline Summarys]
(Source: Journal of Oncology Practice)
Source: Journal of Oncology Practice - January 12, 2016 Category: Cancer & Oncology Authors: Rudin, C. M., Giaccone, G., Ismaila, N. Tags: ASCO Guidelines, Non-ASCO Guidelines, Small Cell, Diagnosis & Staging, Surgery, Radiation, Chemotherapy, Combined Modality, Imaging, Nuclear Medicine and PET, CT, MRI Guideline Summarys Source Type: research