ReCAP: Treatment Patterns and Cost of Care Associated With Initial Therapy Among Patients Diagnosed With Operable Early-Stage Human Epidermal Growth Factor Receptor 2-Overexpressed Breast Cancer in the United States: A Real-World Retrospective Study [CARE DELIVERY]
This study assessed real-world treatment patterns, health care use, and costs associated with initial treatment of resected nonmetastatic human epidermal growth factor receptor 2–overexpressing (HER2+) breast cancer in the United States.
SUMMARY ANSWER:
Although trastuzumab-based therapy is considered standard of care among patients with HER2+ early-stage breast cancer, approximately 28% of these patients did not receive HER2-targeted therapy; in addition, receipt of HER2-targeted therapy differed by hormone receptor status.
METHODS:
Oncology registry data linked to a large US commercial administrative claims datab...
Source: Journal of Oncology Practice - February 11, 2016 Category: Cancer & Oncology Authors: DaCosta Byfield, S., Buck, P. O., Blauer-Peterson, C., Poston, S. A., DaCosta Byfield, S., Buck, P. O., Blauer-Peterson, C., Poston, S. A. Tags: Management and treatment, Cost of care, Pharmacoeconomics, Cost of care, Diagnosis & Staging, Surgery, Population and Observational Studies, Outcomes Research CARE DELIVERY Source Type: research
ReCAP: Feasibility and Accuracy of Extracting Cancer Stage Information From Narrative Electronic Health Record Data [CARE DELIVERY]
QUESTION ASKED:
Cancer stage, one of the most important prognostic factors for cancer-specific survival, is often documented in narrative form in electronic health records (EHRs), and as such is difficult to abstract by registrars and other secondary data users, including clinicians participating in quality reporting activities. Can the cancer stage be accurately extracted by natural language processing (NLP) of the text from EHRs?
SUMMARY ANSWER:
In a combined dataset of N = 2,323 patients with lung cancer (training set: n = 1,103; validation set n = 1,220), we analyzed 751,880 documents and discovered at least one stage...
Source: Journal of Oncology Practice - February 11, 2016 Category: Cancer & Oncology Authors: Warner, J. L., Levy, M. A., Neuss, M. N., Warner, J. L., Levy, M. A., Neuss, M. N. Tags: Electronic health records, Methodology, Electronic health records, Prognostic Studies, Incidence trends, Diagnosis & Staging CARE DELIVERY Source Type: research
ReCAP: Impact of Multidisciplinary Care on Processes of Cancer Care: A Multi-Institutional Study [CARE DELIVERY]
QUESTION ASKED:
What is the relationship between the level of implementation of multidisciplinary care (MDC) and various processes of cancer care (eg, time to treatment receipt, evaluation for enrollment onto a clinical trial) among community cancer centers serving patients diagnosed with colon, rectal, or lung cancer? There is limited generalizable evidence on this topic. It is important to answer this question using data that can generalize across cancer patients, the majority of whom receive treatment in a community cancer center.
SUMMARY ANSWER:
Focusing on the time to receipt of cancer-directed treatment as one key p...
Source: Journal of Oncology Practice - February 11, 2016 Category: Cancer & Oncology Authors: Onukwugha, E., Petrelli, N. J., Castro, K. M., Gardner, J. F., Jayasekera, J., Goloubeva, O., Tan, M. T., McNamara, E. J., Zaren, H. A., Asfeldt, T., Bearden, J. D., Salner, A. L., Krasna, M. J., Das, I. P., Clauser, S. B., Onukwugha, E., Petrelli, N. J., Tags: Population and Observational Studies, Epidemiology, Quality of Care, Guidelines, Epidemiology CARE DELIVERY Source Type: research
ReCAP: Insights Into the Potential Preventability of Oncology Readmissions [CARE DELIVERY]
CONCLUSION:
Three independent reviewers analyzed 72 hospital readmissions and found that 22 (31%) of the 72 readmissions were preventable. The most common causes of preventability were overwhelming symptoms in patients who qualified for hospice but were not participating and insufficient communication between patients and the care team about symptom burden. The most common reason for nonpreventability were high symptom burden among patients not appropriate for hospice or for whom aggressive outpatient management was inadequate despite extensive efforts (Table). Readmissions from nursing facilities—where there is litt...
Source: Journal of Oncology Practice - February 11, 2016 Category: Cancer & Oncology Authors: Meisenberg, B. R., Hahn, E., Binner, M., Weng, D., Meisenberg, B. R., Hahn, E., Binner, M., Weng, D. Tags: Quality of care, Outcomes Research, Quality of Care, Efficiency of Care CARE DELIVERY Source Type: research
ReCAP: Hospitalizations in Older Adults With Advanced Cancer: The Role of Chemotherapy [CARE DELIVERY]
CONCLUSION:
Hospitalizations are common in patients with incurable advanced malignancies and are more likely among those who receive chemotherapy.
APPROACH:
In the linked SEER-Medicare dataset, we identified Medicare beneficiaries aged 66 years or older with a primary diagnosis of metastatic breast, colorectal, ovarian, bladder, lung, pancreas, esophageal, stomach, or prostate cancer between 2001 and 2009 who died by the end of 2010. Chemotherapy recipients and nonrecipients were pair-matched by age, sex, race, comorbidity, geographic region and survival duration. The primary endpoint was hospital admission, identified in...
Source: Journal of Oncology Practice - February 11, 2016 Category: Cancer & Oncology Authors: ONeill, C. B., Atoria, C. L., OReilly, E. M., Henman, M. C., Bach, P. B., Elkin, E. B., ONeill, C. B., Atoria, C. L., OReilly, E. M., Henman, M. C., Bach, P. B., Elkin, E. B. Tags: Older adult (geriatrics), Complications of cancer and cancer treatment, Population and Observational Studies, Outcomes Research, Outcomes Research CARE DELIVERY Source Type: research
ReCAP: Attitudes, Beliefs, and Awareness of Graduate Medical Education Trainees Regarding Palliative Care at a Comprehensive Cancer Center [CARE DELIVERY]
QUESTION ASKED:
What are graduate medical education trainees’ attitudes and beliefs regarding palliative care, what is their awareness of the availability and role of palliative care services, and does previous exposure to a palliative care rotation facilitate a better awareness of palliative care?
SUMMARY ANSWER:
A vast majority of oncology trainees perceived palliative care services to be beneficial for patient care (92%) and were supportive of mandatory palliative care training (74%). Surgical oncology trainees and trainees with no previous palliative care exposure were significantly less likely to consult pallia...
Source: Journal of Oncology Practice - February 11, 2016 Category: Cancer & Oncology Authors: Wong, A., Reddy, A., Williams, J. L., Wu, J., Liu, D., Bruera, E., Wong, A., Reddy, A., Williams, J. L., Wu, J., Liu, D., Bruera, E. Tags: Clinical guidelines, Management and treatment, Clinical guidelines, Complications of cancer and cancer treatment, Training, Supportive care, Quality, Palliative care, Quality of care, Caregiver, General public, Media, Patient, Access to care, Quality of C Source Type: research
ReCAP: Pharmacists Impact in Hematopoietic Stem-Cell Transplantation: Economic and Humanistic Outcomes [CARE DELIVERY]
QUESTION ASKED:
What is the impact of clinical pharmacy services in the care of patients undergoing hematopoietic stem-cell transplantation?
SUMMARY ANSWER:
Pharmacy services in this patient population result in additional revenue generation through pharmacy billing, provider time savings, and outpatient pharmacy prescription referrals. Additionally, both patients and providers have very positive perceptions of the value of pharmacists’ involvement in hematopoietic stem cell transplant care.
METHODS:
Pharmacy services were (1) translated to revenue generated through pharmacy billing and prescription revenue, (2) as...
Source: Journal of Oncology Practice - February 11, 2016 Category: Cancer & Oncology Authors: Alexander, M. D., Rao, K. V., Khan, T. S., Deal, A. M., Alexander, M. D., Rao, K. V., Khan, T. S., Deal, A. M. Tags: Quality of care, Pharmacoeconomics, Reimbursement, Cost Effectiveness, Quality of Care, Efficiency of Care, Pharmacy CARE DELIVERY Source Type: research
ReCAP: ASCO Core Curriculum for Cancer Survivorship Education [CARE DELIVERY]
CONTEXT AND QUESTION(S) ASKED:
The number of cancer survivors is increasing exponentially. Currently there about 15 million cancer survivors, and by 2025, there will be nearly 20 million. Who will provide survivorship care, what are evidenced-based or best care practices, what are best methods to disseminate this information and assess its impact on physician practice, and what are the most cost-effective health care delivery models to serve the majority of survivors?
SUMMARY ANSWER:
The ASCO Survivorship Committee in collaboration with the ASCO Professional Development Committee developed a core curriculum and core compe...
Source: Journal of Oncology Practice - February 11, 2016 Category: Cancer & Oncology Authors: Shapiro, C. L., Jacobsen, P. B., Henderson, T., Hurria, A., Nekhlyudov, L., Ng, A., Surbone, A., Mayer, D. K., Rowland, J. H., Shapiro, C. L., Jacobsen, P. B., Henderson, T., Hurria, A., Nekhlyudov, L., Ng, A., Surbone, A., Mayer, D. K., Rowland, J. H. Tags: Policy, Survivorship, Caregiver, General public, Patient, Survivor CARE DELIVERY Source Type: research
Refining the Standard of Care: How Oncology Treatment Pathways Can Make a Difference [Editorials]
(Source: Journal of Oncology Practice)
Source: Journal of Oncology Practice - February 11, 2016 Category: Cancer & Oncology Authors: Page, R. D. Tags: Clinical guidelines, Management and treatment Editorials Source Type: research
Benefits and Pitfalls of Using Administrative Data to Study Hospitalization Patterns in Patients With Cancer Treated With Chemotherapy [Editorials]
(Source: Journal of Oncology Practice)
Source: Journal of Oncology Practice - February 11, 2016 Category: Cancer & Oncology Authors: Enright, K. A., Krzyzanowska, M. K. Tags: Editorials Source Type: research
Cancer Staging in Electronic Health Records: Strategies to Improve Documentation of These Critical Data [Editorials]
(Source: Journal of Oncology Practice)
Source: Journal of Oncology Practice - February 11, 2016 Category: Cancer & Oncology Authors: Evans, T. L., Gabriel, P. E., Shulman, L. N. Tags: Clinical guidelines, Policy, Quality, Electronic health records, Bioinformatics, Missing Data, IT/EHR Editorials Source Type: research
Geriatricizing Oncology Care: Older Women With Breast Cancer [COMMENTARIES]
(Source: Journal of Oncology Practice)
Source: Journal of Oncology Practice - February 11, 2016 Category: Cancer & Oncology Authors: Lichtman, S. M. Tags: Geriatric Oncology COMMENTARIES Source Type: research
Treatment of Breast Cancer in Women Older Than 80 Years Is a Complex Task [COMMENTARIES]
(Source: Journal of Oncology Practice)
Source: Journal of Oncology Practice - February 11, 2016 Category: Cancer & Oncology Authors: Balducci, L. Tags: Geriatric Oncology COMMENTARIES Source Type: research
Breast Cancer in Women Older Than 80 Years [Clinical Reviews]
Breast cancer is the most common cancer in women, with an incidence that rises dramatically with age. The average age at diagnosis of breast cancer is 61 years, and the majority of woman who die of breast cancer are age 65 years and older. Major improvements in public health and medical care have resulted in dramatic increases in longevity. The oldest old (those age 80 years and older) are a rapidly expanding group and now comprise 9 million members of the US population. The treatment of individuals who are age 80 years and older is complex and involves clearly defining the goals and value of treatment while also weighing ...
Source: Journal of Oncology Practice - February 11, 2016 Category: Cancer & Oncology Authors: Shachar, S. S., Hurria, A., Muss, H. B. Tags: Epidemiology, Diagnosis & Staging, Surgery, Radiation, Chemotherapy, Combined Modality, Hormonal Therapy, Geriatric Oncology Clinical Reviews Source Type: research
Is This As Good As It Gets? [COMMENTARIES]
(Source: Journal of Oncology Practice)
Source: Journal of Oncology Practice - February 11, 2016 Category: Cancer & Oncology Authors: Wozniak, A. J. Tags: Small Cell, Combined Modality COMMENTARIES Source Type: research
