Anaplastic Thyroid Carcinoma: Treatment in the Age of Molecular Targeted Therapy [Clinical Reviews]
Anaplastic thyroid carcinoma is one of the most aggressive and deadly cancers in humans and accounts for one to two cases per million persons annually. The rarity of this malignancy and the rapidity by which it grows has been a major barrier to progress in finding effective therapies. Thus, the treatment that is the current standard of care for these patients is largely palliative, and few are cured; however, novel therapies and approaches are being studied in patients with anaplastic thyroid carcinoma and are delineated herein. (Source: Journal of Oncology Practice)
Source: Journal of Oncology Practice - June 9, 2016 Category: Cancer & Oncology Authors: Cabanillas, M. E., Zafereo, M., Gunn, G. B., Ferrarotto, R. Tags: Management and treatment, Epidemiology, Diagnosis & Staging, Surgery, Radiation, Chemotherapy, Combined Modality, Translational Oncology Clinical Reviews Source Type: research
A Pathway Through the Bundle Jungle [Editorials]
(Source: Journal of Oncology Practice)
Source: Journal of Oncology Practice - June 9, 2016 Category: Cancer & Oncology Authors: Polite, B., Ward, J. C., Cox, J. V., Morton, R. F., Hennessy, J., Page, R., Conti, R. M. Tags: Cost of care, Pharmacoeconomics, Reimbursement, Regulatory issues, Reimbursements Editorials Source Type: research
Using Quality-Adjusted Life-Years in Cost-Effectiveness Analyses: Do Not Throw Out the Baby or the Bathwater [Editorials]
(Source: Journal of Oncology Practice)
Source: Journal of Oncology Practice - June 9, 2016 Category: Cancer & Oncology Authors: Goldstein, D. A. Tags: Cost of care, Pharmacoeconomics, Cost of care, Cost Effectiveness, Outcomes Research, Policy Analysis Editorials Source Type: research
Communicating Disease-Specific Knowledge to Patients: An Overlooked Aspect of Personalized Medicine [Editorials]
(Source: Journal of Oncology Practice)
Source: Journal of Oncology Practice - June 9, 2016 Category: Cancer & Oncology Authors: Wallner, L. P., Hawley, S. T. Tags: Clinical guidelines, Quality of Care Editorials Source Type: research
Journey Toward High Reliability: A Comprehensive Safety Program to Improve Quality of Care and Safety Culture in a Large, Multisite Radiation Oncology Department [FOCUS ON QUALITY]
Conclusion:
Our journey toward becoming an HRO has led to the development of a robust SC through a comprehensive safety framework. Our multifaceted initiatives, focusing on culture and system changes, can be successfully implemented in a large academic radiation oncology department to yield measurable improvements in SC and outcomes. (Source: Journal of Oncology Practice)
Source: Journal of Oncology Practice - May 10, 2016 Category: Cancer & Oncology Authors: Woodhouse, K. D., Volz, E., Maity, A., Gabriel, P. E., Solberg, T. D., Bergendahl, H. W., Hahn, S. M. Tags: Patient safety, Quality of care, Radiation Oncology FOCUS ON QUALITY Source Type: research
Reducing Unplanned Medical Oncology Readmissions by Improving Outpatient Care Transitions: A Process Improvement Project at the Cleveland Clinic [FOCUS ON QUALITY]
Conclusion:
Modest readmission reductions can be achieved through better systematic transitions to outpatient care (including follow-up calls and early provider visits), thereby leading to a reduction in use of inpatient resources. These data suggest that efforts focused on improving outpatient care transition were effective in reducing unplanned oncology readmissions. (Source: Journal of Oncology Practice)
Source: Journal of Oncology Practice - May 10, 2016 Category: Cancer & Oncology Authors: Montero, A. J., Stevenson, J., Guthrie, A. E., Best, C., Goodman, L. M., Shrotriya, S., Azzouqa, A.-G., Parala, A., Lagman, R., Bolwell, B. J., Kalaycio, M. E., Khorana, A. A. Tags: Quality FOCUS ON QUALITY Source Type: research
Time-Driven Activity-Based Costing: A Comparative Cost Analysis of Whole-Breast Radiotherapy Versus Balloon-Based Brachytherapy in the Management of Early-Stage Breast Cancer [BUSINESS OF ONCOLOGY]
Conclusion:
APBI cost more than WBRT when using the dose/fractionation schemes analyzed. Future research should use time-driven activity-based costing to better understand cost with the aim of reducing expenditure and defining bundled payments. (Source: Journal of Oncology Practice)
Source: Journal of Oncology Practice - May 10, 2016 Category: Cancer & Oncology Authors: Schutzer, M. E., Arthur, D. W., Anscher, M. S. Tags: Cost of care, Reimbursement, Financial resources, Surgery, Radiation, Radiation Oncology BUSINESS OF ONCOLOGY Source Type: research
Radiation Oncology Practice: Adjusting to a New Reimbursement Model [BUSINESS OF ONCOLOGY]
Conclusion:
The move to hypofractionation in the United States will lead to increased pressures on departments to address budget shortfalls resulting from the decrease in per-patient revenue. This may be done through a combination of an increase in patient volume, recognition of the increased skill sets required to deliver hypofractionated radiotherapy, delay in capital purchases, and/or reduction in staff. In a value-based environment, these evolutions should improve the value proposition of radiation oncology over a fee-for-service model. (Source: Journal of Oncology Practice)
Source: Journal of Oncology Practice - May 10, 2016 Category: Cancer & Oncology Authors: Konski, A., Yu, J. B., Freedman, G., Harrison, L. B., Johnstone, P. A. S. Tags: Radiation Oncology BUSINESS OF ONCOLOGY Source Type: research
How Well Do All Patient Refined-Diagnosis-Related Groups Explain Costs of Pediatric Cancer Chemotherapy Admissions in the United States? [HEALTH POLICY]
Conclusion:
APR-DRGs developed for adults are applicable to childhood cancer chemotherapy but should be refined to account for cancer diagnosis and patient age. Possible policy and clinical management changes merit further study to address factors not captured by APR-DRGs. (Source: Journal of Oncology Practice)
Source: Journal of Oncology Practice - May 10, 2016 Category: Cancer & Oncology Authors: Russell, H., Street, A., Ho, V. Tags: Coding and Reimbursement, Reimbursement HEALTH POLICY Source Type: research
Presenting Symptoms in the Emergency Department as Predictors of Intensive Care Unit Admissions and Hospital Mortality in a Comprehensive Cancer Center [CARE DELIVERY]
Conclusion:
Patients with cancer admitted through an ED experience high ICU admission and hospital mortality rates. Patients with advanced cancer and respiratory distress or altered mental status may benefit from palliative care that avoids unnecessary interventions. (Source: Journal of Oncology Practice)
Source: Journal of Oncology Practice - May 10, 2016 Category: Cancer & Oncology Authors: Elsayem, A. F., Merriman, K. W., Gonzalez, C. E., Yeung, S.-C. J., Chaftari, P. S., Reyes-Gibby, C., Todd, K. H. Tags: Management and treatment, Quality of life, Supportive care, Palliative care, Quality of care, Organization, Quality of life, Epidemiology, Family member, Access to care, Cost of care, General public, Access to care, Cost of care, Access to care, Clinical Source Type: research
Faster FOLFOX: Oxaliplatin Can Be Safely Infused at a Rate of 1 mg/m2/min [CARE DELIVERY]
Conclusion:
Infusing oxaliplatin at a rate of 1 mg/m2/min does not increase the rate of HSRs and does not compromise patient safety. This infusion rate is safe for use in routine practice. (Source: Journal of Oncology Practice)
Source: Journal of Oncology Practice - May 10, 2016 Category: Cancer & Oncology Authors: Cercek, A., Park, V., Yaeger, R., Reidy-Lagunes, D., Kemeny, N. E., Stadler, Z. K., Segal, N. H., Varghese, A., Saltz, L. B. Tags: Chemotherapy CARE DELIVERY Source Type: research
Assessing Clinical Trial-Associated Workload in Community-Based Research Programs Using the ASCO Clinical Trial Workload Assessment Tool [CARE DELIVERY]
Conclusion:
The results from this project demonstrate that trial-specific acuity measurement is a better measure of workload than simply counting the number of patients. The tool was shown to be feasible and useable in diverse community-based research settings. (Source: Journal of Oncology Practice)
Source: Journal of Oncology Practice - May 10, 2016 Category: Cancer & Oncology Authors: Good, M. J., Hurley, P., Woo, K. M., Szczepanek, C., Stewart, T., Robert, N., Lyss, A., Gonen, M., Lilenbaum, R. Tags: Staff and staffing, Management and treatment, Practice Administration, Clinical Trials, Community Practice CARE DELIVERY Source Type: research
Use of Survivorship Care Plans and Analysis of Patient-Reported Outcomes in Multinational Patients With Lung Cancer [CARE DELIVERY]
Conclusion:
For patients with lung cancer worldwide, it is feasible to obtain PROs and to create SCPs through an Internet-based program. As patients with lung cancer achieve improved survival, further attention should be paid to PROs. Surprisingly, neurocognitive symptoms seem to be the most common issues and therefore the most important to address. Increased effort should be made to provide SCPs, particularly in urban and university cancer center settings. (Source: Journal of Oncology Practice)
Source: Journal of Oncology Practice - May 10, 2016 Category: Cancer & Oncology Authors: Berman, A. T., DeCesaris, C. M., Simone, C. B., Vachani, C., DiLullo, G., Hampshire, M. K., Metz, J., Hill-Kayser, C. Tags: Complications of cancer and cancer treatment, Survivor, Outcomes Research, Radiation Oncology, Combined Modality CARE DELIVERY Source Type: research
Easier Said Than Done: Keys to Successful Implementation of the Distress Assessment and Response Tool (DART) Program [CARE DELIVERY]
Conclusion:
Key factors in the success of DART implementation were the adoption of a programmatic approach, strong institutional commitment, and a primary focus on clinic-based response. We have demonstrated that large-scale routine screening for distress in a cancer center is achievable and has the potential to enhance the cancer care experience for both patients and staff. (Source: Journal of Oncology Practice)
Source: Journal of Oncology Practice - May 10, 2016 Category: Cancer & Oncology Authors: Li, M., Macedo, A., Crawford, S., Bagha, S., Leung, Y. W., Zimmermann, C., Fitzgerald, B., Wyatt, M., Stuart-McEwan, T., Rodin, G. Tags: Communication, Doctor-patient communication, Patient safety, Management and treatment, Complications of cancer and cancer treatment, Communication, Treatment related issues, Doctor-patient communication, Supportive care, Quality, Patient safety, Informati Source Type: research
Readmissions After Colon Cancer Surgery: Does It Matter Where Patients Are Readmitted? [CARE DELIVERY]
Conclusion:
Readmission to a different hospital after colon cancer surgery is associated with short-term mortality but not with long-term mortality nor with post-discharge costs of care. Additional investigation is needed to determine how to improve short-term mortality among patients readmitted to different hospitals. (Source: Journal of Oncology Practice)
Source: Journal of Oncology Practice - May 10, 2016 Category: Cancer & Oncology Authors: Luu, N.-P., Hussain, T., Chang, H.-Y., Pfoh, E., Pollack, C. E. Tags: Cost of care, Outcomes Research, Policy Analysis CARE DELIVERY Source Type: research
