Normal values of the pediatric electrocardiogram, ventricular gradient and QRS-T angle
Normal values of the mathematically-synthesized VCG are lacking for children. Therefore, the objective of this study was to assess normal values of the pediatric synthesized VCG (spatial QRS-T angle [SA] and ventricular gradient [VG]). (Source: Journal of Electrocardiology)
Source: Journal of Electrocardiology - January 6, 2018 Category: Cardiology Authors: Vivian P. Kamphuis, Nico A. Blom, Erik W. van Zwet, Sumche Man, Arend D.J. ten Harkel, Arie C. Maan, Cees A. Swenne Source Type: research

A tribute in life to the world icon of the cardiology of heights: Dr. Dante Pe ñaloza from Peru
Dr. Dante Pe ñaloza is currently considered a living legend of cardiology and particularly, of electro-vectorcardiography in Peru, because of his original contributions made in these areas, to the point of having an important public hospital of this country with his name: “Centro Cardiológico Dr. Dante Peña loza Ramella”. (Source: Journal of Electrocardiology)
Source: Journal of Electrocardiology - January 4, 2018 Category: Cardiology Authors: Jorge Luis Sotomayor-Perales, Edgardo Schapachnik, Raimundo Barbosa-Barros, Andr és Ricardo Pérez-Riera Tags: Review Source Type: research

Recording unipolar ECG leads using one limb of the Wilson Central Terminal
Introduction: Since Frank Wilson first proposed “unipolar” surface ECG leads in 1931, the use of the Wilson Central Terminal (WCT) has become the standard electrical reference for the Augmented Limb leads, the Chest Leads and intracardiac catheter electrograms. Wilson's notion of a reference potential at an “infinite” distance providing a zero-volt reference has proved to be mistaken but is a de facto standard. We hypothesized that an equivalent “far field” reference could be obtained by using only one of the limbs of the WCT, enabling the recording of a 12-lead ECG using a single bipolar pair of electrodes. (S...
Source: Journal of Electrocardiology - January 1, 2018 Category: Cardiology Authors: David E. Albert, Michael H. Albert, Brigitte N. Sallee, Conner Wann, Landgrave Smith Source Type: research

Variability of human-annotations of 12-lead ECG features collected using a web system: Students vs. practitioners
Introduction: The electrocardiogram (ECG) is often interpreted incorrectly with up to 33% of interpretations containing a significant error. The difficulty in ECG interpretation is two-fold; 1) it demands an extensive knowledge of cardiac physiology, and 2) the ECG inflates cognitive workload due to the complex nature of its presentation. To make a diagnosis, the reader is required to measure ECG features in order to contrast these annotations with diagnostic criteria. Whilst signal processing algorithms can provide automated measurements, they are often imprecise. (Source: Journal of Electrocardiology)
Source: Journal of Electrocardiology - January 1, 2018 Category: Cardiology Authors: Andrew W. Cairns, Raymond R. Bond, Dewar D. Finlay, Daniel Guldenring, Cathal Breen, Aaron Peace Source Type: research

Electrocardiographic scores of severity and acuteness of myocardial ischemia predict myocardial salvage in patients with anterior ST-segment elevation myocardial infarction
Objectives: Terminal “QRS distortion” on the electrocardiogram (ECG) is a sign of severe ischemia, associated with rapid progression of myocardial necrosis and larger infarct size in ST-segment elevation myocardial infarction (STEMI). In addition, ECG indices of the acuteness of ischemia indicate myocardial salvage potential. We assessed whether severe ischemia with or without acute ischemia is predictive of infarct size (IS), myocardial salvage index (MSI) and left ventricular ejection fraction (LVEF) in anterior versus inferior infarct locations. (Source: Journal of Electrocardiology)
Source: Journal of Electrocardiology - January 1, 2018 Category: Cardiology Authors: Yama Fakhri, Maria Sejersten, Mikkel Malby Schoos, Henrik Steen Hansen, Jean-Luc Dubois-Rande, Alf-Inge Larsen, Svend Eggert Jensen, Hakon Arheden, Jens Kastrup, Dan Atar, Peter Clemmensen Source Type: research

Can vectorcardiogram criteria unmask inferior Q-waves in Mason-Likar 12-lead ECG?
Background: Torso placement of 12-lead ECG electrodes is commonly used to reduce noise. The main differences between Mason-Likar (torso) and standard placement on wrists and ankles are frontal plane QRS-axis and missing Q-waves with inferior myocardial infarction (IMI). We developed and tested a combination of Frank orthogonal lead estimation, Mason-Likar (ML) correction and VCG criteria to maintain adequate inferior MI (IMI) detection with torso electrode placement. (Source: Journal of Electrocardiology)
Source: Journal of Electrocardiology - January 1, 2018 Category: Cardiology Authors: Richard E. Gregg, Sophia H. Zhou, Saeed Babaeizadeh Source Type: research

Limitations of the smartphone based single ECG-lead evaluation of STEMI
Introduction: Potential applications for smartphone based electrocardiogram (ECG) analysis are currently being explored. Previous research has predominantly focused on the feasibility of smartphone based single ECG-lead rhythm evaluation. More recently, there has also been interest in the utility of smartphone based single ECG-lead measurements for the evaluation of ST segment elevation myocardial infarction (STEMI). A recent study reported “excellent concordance” between “12-lead equivalent ECGs” that were recorded using smartphone technology and the standard 12-lead ECG. (Source: Journal of Electrocardiology)
Source: Journal of Electrocardiology - January 1, 2018 Category: Cardiology Authors: Daniel Guldenring, Dewar D. Finlay, Raymond R. Bond, Alan Kennedy, James McLaughlin Source Type: research

Map of thorough QT studies with QTc and J-Tpeakc biomarkers
In this study, we have analyzed ECG effects caused by multiple drugs from thorough QT (TQT) studies to explore QTc and J-Tpeakc as indicators of predominant hERG versus multi-channel blockers. (Source: Journal of Electrocardiology)
Source: Journal of Electrocardiology - January 1, 2018 Category: Cardiology Authors: Meisam Hosseini, Jose Vicente, Lars Johannesen, Alexander Wong, Dustin C. McAfee, Norman Stockbridge, David G. Strauss Source Type: research

QT-prolongation in type 1 diabetes is augmented during bradycardia
Background: Sudden unexplained death in the young has been described in type-1 diabetes (T1DM), and QT-prolongation has been suggested as the underlying mechanism. The syndrome has been termed the “dead-in-bed syndrome” since patients most often are found dead after a period of undisturbed rest. We investigated differences in the QT-interval in ambulatory T1DM patients without known heart disease compared to age- and sex-matched controls. (Source: Journal of Electrocardiology)
Source: Journal of Electrocardiology - January 1, 2018 Category: Cardiology Authors: Jonas L. Isaksen, Claus Graff, Christina Ellervik, Peter Rossing, Jan Skov Jensen, Jorgen K. Kanters, Magnus T. Jensen Source Type: research

Genome-wide association study of T-wave morphology
Introduction: T wave morphology has been shown to contain different information regarding cardiac ion currents compared to the classical QT interval. Block of the HERG potassium current, IKr, gives characteristic T-wave features like flattening, skewing of the T-wave often with visible humps. Morphology Combination Score (MCS) has been developed as a better HERG block indicator then the QT interval. The aim of the study was to investigate the influence of normal genetic variation on MCS. (Source: Journal of Electrocardiology)
Source: Journal of Electrocardiology - January 1, 2018 Category: Cardiology Authors: J.K. Kanters, N. Grarup, C. Graff, J. Nielsen, A. Linneberg, T. Hansen, M.S. Olesen Source Type: research

Visible but wide QRS complexes are associated with false asystole alarms
Background: Bedside electrocardiographic (ECG) monitoring is a mainstay used for continuous surveillance of intensive care unit (ICU) patients. However, false ECG alarms are common, and contribute to alarm fatigue, a problem linked to untoward patient outcomes. Critical arrhythmia alarms such as asystole are configured as “latching” alarms, which cannot be silenced until they are physically muted at the bedside monitor or central nursing station. This contributes to alarm fatigue, and distracts nurses from patient care. (Source: Journal of Electrocardiology)
Source: Journal of Electrocardiology - January 1, 2018 Category: Cardiology Authors: Michele M. Pelter, Richard Fidler, Xiao Hu Source Type: research

Torso mesh and body surface electrodes position reconstruction using a Kinect camera
Body surface (BS) potentials technology has gained more acceptance in the clinical community due to the extra information it may provide. Based on 3D computational structures and multi-electrode systems, the torso mesh and electrodes position are usually obtained from MRI or CT-scan data. However, both methods have their drawbacks, such as ionizing radiation exposure, added cost of MRI/CT friendly electrodes/markers and additional time investment and potential discomfort to the patient. Therefore, there is a pressing need to develop new methods of BS electrodes position registration to lower costs while improving convenien...
Source: Journal of Electrocardiology - January 1, 2018 Category: Cardiology Authors: Erick A. Perez-Alday, Jason Thomas, Muammar Kabir, Golriz Sedaghat, Eelco van Dam, Peter van Dam, Larisa G. Tereshchenko Source Type: research

A Kalman filter based adaptive impulse correlated filter
Introduction: The filtering of baseline wander in ECG signals is a long-standing problem that is particularly challenging because the frequency content of an ECG often overlaps with the frequency content of the baseline wander. (Source: Journal of Electrocardiology)
Source: Journal of Electrocardiology - January 1, 2018 Category: Cardiology Authors: Ramun Schmid, Roger Ab ächerli, Gianluca Generali Source Type: research

Diagnostic and prognostic value of the QRS-T-angle, an ECG marker quantifying heterogeneity of depolarization and repolarization, in patients with suspected non-ST-elevation myocardial infarction
Background: The value of the 12-lead ECG in the diagnosis of non-ST-elevation myocardial infarction (NSTEMI) is limited due to insufficient sensitivity and specificity of standard markers of ischemia and because ECG confounders may prevent their application. The QRS-T-angle reflects depolarization –repolarization heterogeneity and might assist in diagnosis and prognosis of patients with suspected NSTEMI. (Source: Journal of Electrocardiology)
Source: Journal of Electrocardiology - January 1, 2018 Category: Cardiology Authors: Ivo Strebel, Raphael Twerenbold, Jasper Boeddinghaus, Roger Ab ächerli, Janosch Cupa, Maria Rubini Giménez, Karin Wildi, Karin Grimm, Christian Puelacher, Stefan Osswald, Christian Mueller, Tobias Reichlin Source Type: research