Association between typical electrocardiographic abnormalities and NT-proBNP elevation in a large cohort of patients with Chagas disease from endemic area
Chagas cardiomyopathy is the most harmful complication of Chagas disease. The electrocardiogram is a well-studied exam and has been considered an important tool for detection and evaluation of Chagas cardiomyopathy since the first years of its description. Many of its abnormalities have been described as associated with a worse prognosis. Serum BNP levels were described as inversely related to the left ventricular ejection fraction and as an independent predictor of death. It was not reported how electrocardiographic alterations correlate to NT-proBNP and its analog. (Source: Journal of Electrocardiology)
Source: Journal of Electrocardiology - August 22, 2018 Category: Cardiology Authors: Bruno Oliveira de Figueiredo Brito, Marcelo Martins Pinto Filho, Clareci Silva Cardoso, Claudia Di Lorenzo Oliveira, Ariela Mota Ferreira, Lea Campos de Oliveira, Paulo Gomes, Maria do Carmo Pereira Nunes, Ester Cerdeira Sabino, Antonio Luiz Pinho Ribeiro Source Type: research

Brugada phenocopy associated with left ventricular aneurysm
We describe the case of a 41-year-old male who exhibited BrP due to a left ventricular aneurysm in the context of chronic coronary artery disease. (Source: Journal of Electrocardiology)
Source: Journal of Electrocardiology - August 22, 2018 Category: Cardiology Authors: Enes Elvin Gul, Sohaib Haseeb, Osama Al Amoudi, Adrian Baranchuk Source Type: research

A method to extract realistic artifacts from electrocardiogram recordings for robust algorithm testing
We present a method to estimate device-specific signal noise and artifacts from ECG records. This method can be applied to obtain noise estimates from healthy subjects on any ECG lead, allowing a simple device-specific recording. The proposed approach is assessed using the MIT-BIH Noise Stress Test Database recordings combined with simulated ECGs. (Source: Journal of Electrocardiology)
Source: Journal of Electrocardiology - August 18, 2018 Category: Cardiology Authors: Loriano Galeotti, Christopher G. Scully Source Type: research

A new criterion to differentiate atrioventricular nodal reentrant tachycardia from atrioventricular reciprocating tachycardia: Combined AVR criterion
A combined aVR criterion is described as the presence of a pseudo r ′ wave in aVR during tachycardia in patients without r′ wave in aVR in sinus rhythm and/or a ≥50% increase in r′ wave amplitude compared to sinus rhythm in patients with r′ wave in the basal aVR lead. We aimed to investigate the use of combined aVR criterion in differential diagnosis of at rioventricular nodal reentrant tachycardia (AVNRT) and atrioventricular reciprocating tachycardia (AVRT). (Source: Journal of Electrocardiology)
Source: Journal of Electrocardiology - August 18, 2018 Category: Cardiology Authors: Abdullah Orhan Demirta ş, Yahya Kemal Icen, Onur Kaypaklı, Hasan Koca, İlker Ünal, Zikret Köseoğlu, Durmus Yıldıray Sahin, Mevlut Koc Source Type: research

FDA perspective on assessing the clinical benefit of cardiac resynchronization and implantable cardioverter-defibrillator devices
Over the past couple of decades, the clinical benefit of implantable cardioverter defibrillators (ICDs) and cardiac resynchronization therapy (CRT) devices has been shown in several large randomized controlled trials [1 –5]. ICDs have been shown to reduce the risk of sudden cardiac death and ventricular fibrillation, and CRTs have been shown to benefit patients with heart failure in terms of improvements in cardiac function, with a reduction in mortality and heart failure hospitalizations. Given the rapid pace of technological advances in electrophysiology devices over the last decade and the widespread use of these devi...
Source: Journal of Electrocardiology - August 18, 2018 Category: Cardiology Authors: Kimberly A. Selzman Source Type: research

The role of epicardial fat as a local mediator of atrial fibrosis
Atrial fibrillation (AF) is the most common arrhythmia in the clinical setting and associated with severe consequences. In recent years, studies on the fundamental underlying pathophysiology of AF revealed electrical, contractile and structural remodeling were synergistic contributors to AF substrate. Fibrosis was the intersection point for different remodeling processes with common endpoint of promoting and maintaining AF [1]. Despite the fact that myocardial ischemia was consistently found to be the major preceding event for fibrosis in ventricular myocardium, there is much weaker evidence for atrial ischemia causing atr...
Source: Journal of Electrocardiology - August 18, 2018 Category: Cardiology Authors: G öksel Çinier, Emrah Bozbeyoğlu, Ahmet İlker Tekkeşin Source Type: research

Reply to the letter to the editor: Successful catheter ablation of ventricular fibrillation
We have recently read with great interest the article by Gul EE, entitled ‘Successful catheter ablation of ventricular fibrillation: Which premature ventricular complexes should we target?’ which was published in the last issue of the Journal of Electrocardiology [1]. First of all, we would like to thank the author for his interest in our case report. We aimed to prov ide a valuable clinical insight for the literature with this case which is difficult to manage and treat [2]. (Source: Journal of Electrocardiology)
Source: Journal of Electrocardiology - August 18, 2018 Category: Cardiology Authors: Abdulkadir Uslu, Ahmet Guner, Sabahattin Gunduz Source Type: research

Unexpected and undesired side-effects of pacing algorithms during exercise
While the implantable pacemaker has initially been developed to treat symptomatic bradycardia, we demand of modern devices that they also function properly during exercise. In recent years, device manufacturers have implemented multiple proprietary algorithms which aim to improve pacemaker function by avoiding unnecessary right ventricular pacing, optimizing atrial refractory periods and diagnosing pacemaker mediated tachycardia. When activated, these algorithms may save the associated EGM into the device memory which enables later analysis by remote monitoring or device interrogation. (Source: Journal of Electrocardiology)
Source: Journal of Electrocardiology - August 17, 2018 Category: Cardiology Authors: M. Strik, Pierre Soci é, S. Ploux, P. Bordachar Source Type: research

How the S-ICD (subcutaneous implantable cardiac defibrillator) senses cardiac signals to minimize cardiac over-sensing and maximize rhythm discrimination
Transvenous Implantable Cardioverter Defibrillator (TV-ICD) and subcutaneous ICD (S-ICD) devices are available for patients at risk of sudden cardiac death (SCD). Both devices sense ventricular arrhythmias with near 100% sensitivity (Gold et al., 2012) and have similar rates of inappropriate shocks (IAS) (2.5 –4.8%). IAS due to supraventricular tachycardias (SVT) is higher for TV-ICDs and IAS due to cardiac over-sensing is higher for S-ICDs (Basu-Ray et al., 2017).The S-ICD's sensing signal is morphologically rich, resembling the surface electrocardiogram (ECG) signal. (Source: Journal of Electrocardiology)
Source: Journal of Electrocardiology - August 17, 2018 Category: Cardiology Authors: Amy Brisben Source Type: research

Resolution of fetal second-degree atrioventricular block
Fetal atrioventricular (AV) block is a rare and potentially devastating condition. Most commonly fetal AV block is mediated by maternal lupus antibodies which cause irreversible damage to the AV node. For many fetuses, the only potential intervention is premature delivery and highly invasive pacemaker implantation. However, there exists a small subset of fetuses with non-immune mediated AV block who appear to have far better outcomes, with potential for spontaneous resolution and a return to sinus rhythm. (Source: Journal of Electrocardiology)
Source: Journal of Electrocardiology - August 17, 2018 Category: Cardiology Authors: Alex Newbury, Michael Fahey Source Type: research

How can we answer more questions about the association between myocardial repolarization parameters and stroke?
To the Editor, (Source: Journal of Electrocardiology)
Source: Journal of Electrocardiology - August 15, 2018 Category: Cardiology Authors: Mert İlker Hayıroğlu, Ceyhan Türkkan, Emrah Bozbeyoğlu Source Type: research

Painful left bundle branch block syndrome treated with his bundle pacing
We report for the first-time complete resolution of chest pain with His bundle pacing. HBP provid es a promising alternative pacing option that might provide symptom resolution to patients with a painful LBBB syndrome. (Source: Journal of Electrocardiology)
Source: Journal of Electrocardiology - August 14, 2018 Category: Cardiology Authors: Juan F. Viles-Gonzalez, Indrajeet Mahata, Elad Anter, Andre d'Avila Source Type: research

Mini-electrodes help identifying hidden slow conduction during ventricular tachycardia substrate ablation
A 69-year-old male with dilated non-ischemic cardiomyopathy and history of sustained monomorphic VT (SMVT) underwent an unsuccessful VT substrate ablation due to the proximity of the earliest activation site to the conduction system. A second attempt was performed using an ablation catheter with mini-electrodes (ME) and multiple extrastimuli to unveil hidden slow conduction (HSC) sites, allowing the performance of a successful ablation. No SMVT was induced thereafter.ME-obtained electrograms permit to accurately localize areas of HSC sites within ventricular tachycardia (VT) substrates. (Source: Journal of Electrocardiology)
Source: Journal of Electrocardiology - August 13, 2018 Category: Cardiology Authors: David Soto-Iglesias, David Andreu, Beatriz J áuregui, Markus Linhart, Lluis Mont, Antonio Berruezo Source Type: research

Criteria for ECG detection of acute myocardial ischemia: Sensitivity versus specificity
Criteria for electrocardiographic detection of acute myocardial ischemia recommended by the Consensus Document of ESC/ACCF/AHA/WHF consist of two parts: The ST elevation myocardial infarction (STEMI) criteria based on ST elevation (ST ↑) in 10 pairs of contiguous leads and the other on ST depression (ST↓) in the same 10 contiguous pairs. Our aim was to assess sensitivity (SE) and specificity (SP) of these criteria—and to seek their possible improvements—in three databases of 12‑lead ECGs. (Source: Journal of Electrocardiology)
Source: Journal of Electrocardiology - August 13, 2018 Category: Cardiology Authors: John J. Wang, Olle Pahlm, James W. Warren, John L. Sapp, B. Milan Hor áček Source Type: research

Temporal performance of Laplacian eigenmaps and 3D conduction velocity in detecting ischemic stress
Myocardial ischemia has a complex and time-varying electrocardiographic signature that is used to diagnose and stratify severity. Despite the ubiquitous clinical use of the ECG to detect ischemia, the sensitivity and specificity of ECG based detection of myocardial ischemia are still inadequate. (Source: Journal of Electrocardiology)
Source: Journal of Electrocardiology - August 13, 2018 Category: Cardiology Authors: Wilson W. Good, Burak Erem, Brian Zenger, Jaume Coll-Font, Dana H. Brooks, Rob S. MacLeod Source Type: research