Map of thorough QT studies with QTc and J-Tpeakc biomarkers

In this study, we have analyzed ECG effects caused by multiple drugs from thorough QT (TQT) studies to explore QTc and J-Tpeakc as indicators of predominant hERG versus multi-channel blockers.

Source: Journal of Electrocardiology - January 1, 2018 Category: Cardiology Authors: Meisam Hosseini, Jose Vicente, Lars Johannesen, Alexander Wong, Dustin C. McAfee, Norman Stockbridge, David G. Strauss Source Type: research