A case report of successful permanent pacemaker implantation via the iliac vein
Publication date: Available online 11 November 2015 Source:Journal of Arrhythmia Author(s): Tetsuo Yamaguchi, Takamichi Miyamoto, Yasuteru Yamauchi, Tohru Obayashi An 85-year-old man was referred to our hospital with a pacemaker pocket infection. A permanent pacemaker had been implanted via the right subclavian vein. The pacemaker and pacing leads were removed and a temporary pacemaker was implanted. After vancomycin treatment for 4 weeks, pacemaker implantation via the right external iliac vein was performed under local anesthesia because of left subclavian vein occlusion, infection of the right pocket, and di...
Source: Journal of Arrhythmia - January 11, 2016 Category: Cardiology Source Type: research

Influence of primary and secondary prevention indications on anxiety about the implantable cardioverter-defibrillator
Conclusions In our study population, which mostly consisted of New York Heart Association (NYHA) class I and II subjects, primary prevention ICD recipients were more prone to experience worries about their ICD, anxiety, and a poorer QOL compared to secondary prevention ICD recipients. In clinical practice, primary prevention ICD patients should be closely monitored. If warranted, they should be offered psychological intervention, as anxiety and low QOL were predictors of mortality. (Source: Journal of Arrhythmia)
Source: Journal of Arrhythmia - January 11, 2016 Category: Cardiology Source Type: research

Molecular autopsy in victims of inherited arrhythmias
Publication date: Available online 19 November 2015 Source:Journal of Arrhythmia Author(s): Christopher Semsarian, Jodie Ingles Sudden cardiac death (SCD) is a rare but devastating complication of a number of underlying cardiovascular diseases. While coronary artery disease and acute myocardial infarction are the most common causes of SCD in older populations, inherited cardiac disorders comprise a substantial proportion of SCD cases aged less than 40 years. Inherited cardiac disorders include primary inherited arrhythmogenic disorders such as familial long QT syndrome (LQTS), Brugada syndrome (BrS), catecholaminer...
Source: Journal of Arrhythmia - January 11, 2016 Category: Cardiology Source Type: research

Conservative therapy for the management of cardiac implantable electronic device infection
Publication date: Available online 19 November 2015 Source:Journal of Arrhythmia Author(s): Yukio Sekiguchi Along with the increased frequency of implantation, the incidence of cardiac implantable electronic device (CIED) infection, which can have serious or fatal complications, has also increased. Although several successful conservative therapies for CIED infection have been reported, retained infected devices remain a source of relapse, which is closely related to a higher mortality rate. Presently, complete hardware removal is initially recommended for infected CIED patients, and indications for conservative ther...
Source: Journal of Arrhythmia - January 11, 2016 Category: Cardiology Source Type: research

Inherited bradyarrhythmia: A diverse genetic background
Publication date: Available online 19 November 2015 Source:Journal of Arrhythmia Author(s): Taisuke Ishikawa, Yukiomi Tsuji, Naomasa Makita Bradyarrhythmia is a common heart rhythm abnormality comprising number of diseases and is associated with decreased heart rate due to the failure of action potential generation and propagation at the sinus node. Permanent pacemaker implantation is often used therapeutically to compensate for decreased heart rate and cardiac output. The vast majority of bradyarrhythmia cases are attributable either to aging or to structural abnormalities of the cardiac conduction system, cause...
Source: Journal of Arrhythmia - January 11, 2016 Category: Cardiology Source Type: research

Successful intraprocedural anticoagulation with bivalirudin during pulmonary vein isolation in a patient with known heparin-induced thrombocytopenia type II
We report the case of a 56-year-old female who presented with symptomatic paroxysmal atrial fibrillation. Anamnestic heparin-induced thrombocytopenia (HIT) type II was suspected, and a rapid diagnostic test showed antibodies against platelet factor 4. The heparin-induced platelet activation-assay was negative. Radiofrequency pulmonary vein isolation with intraprocedural anticoagulation using bivalirudin was ultimately performed. Dosing was controlled by monitoring the activated clotting time. Post-procedural blood tests were normal. There were no thromboembolic or bleeding events. Bivalirudin is a therapeutic option for an...
Source: Journal of Arrhythmia - January 11, 2016 Category: Cardiology Source Type: research

Current topics in catecholaminergic polymorphic ventricular tachycardia
Publication date: Available online 24 November 2015 Source:Journal of Arrhythmia Author(s): Naokata Sumitomo Catecholaminergic polymorphic ventricular tachycardia (CPVT) is induced by emotions or exercise in patients without organic heart disease and may be polymorphic or bidirectional in nature. The prognosis of CPVT is not good, and therefore prevention of sudden death is of utmost importance. Genetic variants of CPVT include RyR2, CASQ2, CALM2, TRD, and possibly KCNJ2 and ANK2 gene mutations. Hypotheses that suggest the causes of CPVT include weakened binding of FKBP12.6 and RyR2, a store overload-induced Ca2+ rel...
Source: Journal of Arrhythmia - January 11, 2016 Category: Cardiology Source Type: research

Initial experience and treatment of atrial fibrillation using a novel irrigated multielectrode catheter: Results from a prospective two-center study
Conclusions PV isolation with a circular irrigated multielectrode ablation catheter is a feasible technique with a high acute success rate. The majority of patients remained asymptomatic during the midterm follow-up period. PV stenosis was not detected. While only a single serious adverse event occurred, this technique׳s safety profile should be tested in larger studies. (Source: Journal of Arrhythmia)
Source: Journal of Arrhythmia - January 11, 2016 Category: Cardiology Source Type: research

Translation and validation of the Malay version of the Stroke Knowledge Test
Conclusions Malay version Stroke Knowledge Test was a valid and reliable tool to assess educational needs and to evaluate stroke knowledge among participants of group-based stroke education programs in Malaysia. (Source: Journal of Arrhythmia)
Source: Journal of Arrhythmia - January 11, 2016 Category: Cardiology Source Type: research

Characterization of the novel mutant A78T-HERG from a long QT syndrome type 2 patient: Instability of the mutant protein and stabilization by heat shock factor 1
Conclusions A78T-HERG was characterized by protein instability and reduced expression on the plasma membrane. The stability of the mutant was partially restored by HSF-1, indicating that HSF-1 is a target for the treatment for LQT2 caused by the A78T mutation in HERG. (Source: Journal of Arrhythmia)
Source: Journal of Arrhythmia - January 11, 2016 Category: Cardiology Source Type: research

Usefulness of filtered unipolar electrogram morphology for evaluating transmurality of ablated lesions during pulmonary vein isolation
Conclusion Filtered UP electrograms may be useful in assessing the effectiveness of lesion formation. (Source: Journal of Arrhythmia)
Source: Journal of Arrhythmia - January 11, 2016 Category: Cardiology Source Type: research

An overlap of Brugada syndrome and arrhythmogenic right ventricular cardiomyopathy/dysplasia
Publication date: Available online 30 November 2015 Source:Journal of Arrhythmia Author(s): Shohei Kataoka, Naoki Serizawa, Kazutaka Kitamura, Atsushi Suzuki, Tsuyoshi Suzuki, Tsuyoshi Shiga, Morio Shoda, Nobuhisa Hagiwara Overlapping characteristics of Brugada syndrome (BrS) and arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D) have been reported in recent studies, but little is known about the overlapping disease state of BrS and ARVC/D. A 36-year-old man, hospitalized at our institution for syncope, presented with this overlapping disease state. The electrocardiogram showed spontaneo...
Source: Journal of Arrhythmia - January 11, 2016 Category: Cardiology Source Type: research

Combined catheter ablation for atrial fibrillation and Watchman® left atrial appendage occlusion procedures: Five-year experience
Conclusions Combined procedures of catheter ablation for AF and Watchman® LAA implant appear to be feasible and safe, with excellent rates of LAA occlusion achieved and an observed stroke rate of 0.5% per year during mid-term follow-up. Incomplete occlusion was associated with lower achieved device compression and was more frequently associated with suboptimal device position. (Source: Journal of Arrhythmia)
Source: Journal of Arrhythmia - January 11, 2016 Category: Cardiology Source Type: research

Differential diagnostic dilemma between pulmonary embolism and acute coronary syndrome
Publication date: Available online 9 December 2015 Source:Journal of Arrhythmia Author(s): Enes Elvin Gul, Kjell C. Nikus, Halil I. Erdogan, Kurtulus Ozdemir Acute pulmonary embolism (PE) is a frequent life-threatening condition in emergency departments. Careful diagnosis is important, and different diagnostic tests such as electrocardiogram (ECG), biochemical markers, echocardiogram, and computed tomography are required. Although ECG is a cheap and rapid diagnostic test for pulmonary embolism, it has some limitations in the differential diagnosis of acute coronary syndrome and acute PE. Herein, we report ECG r...
Source: Journal of Arrhythmia - January 11, 2016 Category: Cardiology Source Type: research

Outcomes of single- or dual-chamber implantable cardioverter defibrillator systems in Japanese patients
Conclusions Dual-chamber ICDs were four-fold more common in Japanese patients without a pacing indication. No benefit over single-chamber ICD was observed. Newly developed atrial pacing-dependency seemed to be limited and could have been overestimated due to higher pacing rate settings in dual-chamber patients. (Source: Journal of Arrhythmia)
Source: Journal of Arrhythmia - January 11, 2016 Category: Cardiology Source Type: research