Successful cryoballoon pulmonary vein isolation in a patient with situs inversus and dextrocardia
Publication date: Available online 23 April 2016 Source:Journal of Arrhythmia Author(s): Yasuhiro Yoshiga, Akihiko Shimizu, Takeshi Ueyama, Makoto Ono, Tomoko Fumimoto, Hironori Ishiguchi, Masafumi Yano A 79-year-old man with situs inversus and dextrocardia underwent catheter ablation of symptomatic paroxysmal atrial fibrillation. Pulmonary vein isolation (PVI), using second-generation cryoballoon under Ensite NavX system guidance, was performed successfully in a reverse manner, which required short procedure and fluoroscopy times, as required in a PVI performed on a normal heart without any complications...
Source: Journal of Arrhythmia - April 25, 2016 Category: Cardiology Source Type: research

Atriofascicular pathway detection with novel ablation catheter
Publication date: Available online 25 April 2016 Source:Journal of Arrhythmia Author(s): Padmanabhan Shakkottai, Adrian Baranchuk, Neil Hobson, Jane Caldwell Atriofascicular pathways are a rare cause of antidromic atrioventricular reciprocating tachycardia. The IntellaTip MiFi ablation catheter (Boston Scientific, MA, USA) is a novel ablation catheter that allows enhanced signal clarity with highly localized electrograms. This is the first report of this catheter being successfully used to map and ablate the atriofascicular pathway potentials. (Source: Journal of Arrhythmia)
Source: Journal of Arrhythmia - April 25, 2016 Category: Cardiology Source Type: research

Temporal sinus node modification by high-dose continuous intravenous administration of landiolol in a patient with persistent inappropriate sinus tachycardia
Publication date: Available online 25 April 2016 Source:Journal of Arrhythmia Author(s): Yuichi Hori, Shiro Nakahara, Naofumi Anjo, Yoshihiko Sakai, Isao Taguchi A 20-year-old woman underwent an electrophysiological study for drug-resistant persistent inappropriate sinus tachycardia (IST). Use of a high-dose continuous intravenous administration of landiolol, a short-acting beta-adrenoreceptor blocker, made the patient׳s heart rate suddenly drop with a slight change in the P-wave morphology. Three-dimensional right atrial (RA) activation mapping revealed that the earliest activation site moved 8mm to a lower...
Source: Journal of Arrhythmia - April 25, 2016 Category: Cardiology Source Type: research

Efficacy of atorvastatin in prevention of atrial fibrillation after heart valve surgery in the PROFACE trial (PROphylaxis of postoperative atrial Fibrillation After Cardiac surgEry)
Conclusions Atorvastatin in the described dose, was not adequate for the prophylaxis of POAF after heart valve surgery. It was ineffective in controlling the inflammatory phenomena, myocardial injury, and echocardiographic predictors of POAF. (Source: Journal of Arrhythmia)
Source: Journal of Arrhythmia - March 28, 2016 Category: Cardiology Source Type: research

Cardiac dynamics: Alternans and arrhythmogenesis
Publication date: Available online 28 March 2016 Source:Journal of Arrhythmia Author(s): Gary Tse, Sheung Ting Wong, Vivian Tse, Yee Ting Lee, Hiu Yu Lin, Jie Ming Yeo Pre-existing heterogeneities present in cardiac tissue are essential for maintaining the normal electrical and mechanical functions of the heart. Exacerbation of such heterogeneities or the emergence of dynamic factors can produce repolarization alternans, which are beat-to-beat alternations in the action potential time course. Traditionally, this was explained by restitution, but additional factors, such as cardiac memory, calcium handling d...
Source: Journal of Arrhythmia - March 27, 2016 Category: Cardiology Source Type: research

Lead extractions in patients with cardiac implantable electronic device infections: Single center experience
Conclusion The current status of CIED infections in Japan seems to be similar to that previously reported from foreign countries. The optimal treatment of CIED infections involves the complete explantation of all hardware, followed by antibiotic therapy. (Source: Journal of Arrhythmia)
Source: Journal of Arrhythmia - March 21, 2016 Category: Cardiology Source Type: research

Double twiddle trouble, a new variant of twiddler syndrome
We describe the first reported case of a dramatic pacemaker lead coiling with a double level of lead compromise, with one of them being intra-cardiac. This condition affected our treatment strategy, as the repositioning of the lead was unfeasible. (Source: Journal of Arrhythmia)
Source: Journal of Arrhythmia - March 21, 2016 Category: Cardiology Source Type: research

New horizon for infection prevention technology and implantable device
Publication date: Available online 19 March 2016 Source:Journal of Arrhythmia Author(s): Yusuke Kondo, Marehiko Ueda, Yoshio Kobayashi, Joerg O. Schwab There has been a significant increase in the number of patients receiving cardiovascular implantable electronic devices (CIED) over the last two decades. CIED infection represents a serious complication after CIED implantation and is associated with significant morbidity and mortality. Recently, newly advanced technologies have offered attractive and suitable therapeutic alternatives. Notably, the leadless pacemaker and anti-bacterial envelope decrease the poten...
Source: Journal of Arrhythmia - March 19, 2016 Category: Cardiology Source Type: research

ST elevation without cardio-pulmonary symptoms
Publication date: Available online 17 March 2016 Source:Journal of Arrhythmia Author(s): Priyank Shah, Rahul Vasudev, Fayez Shamoon (Source: Journal of Arrhythmia)
Source: Journal of Arrhythmia - March 18, 2016 Category: Cardiology Source Type: research

Resolution of a warfarin and dabigatran-resistant left atrial appendage thrombus with apixaban
Publication date: Available online 15 March 2016 Source:Journal of Arrhythmia Author(s): Yosuke Miwa, Toshinori Minamishima, Toshiaki Sato, Konomi Sakata, Hideaki Yoshino, Kyoko Soejima The majority of embolisms associated with atrial fibrillation (AF) are from the left atrial appendage (LAA). To treat the existing thrombus, warfarin and novel anticoagulants have been used. However, there has been no clinical information regarding the difference of the effects of congealing the fibrinogenolysis system among these oral anticoagulants. Here, we report a case of persistent AF, in whom apixaban, factor Xa inhib...
Source: Journal of Arrhythmia - March 16, 2016 Category: Cardiology Source Type: research

Clinical and genetic features of Australian families with long QT syndrome: A registry-based study
Conclusions This is the first clinical and genetic study in a large cohort of Australian families with LQTS. Findings from this study suggest that the clinical and genetic features in this population are not dissimilar to those described in North American, European, and Asian cohorts. Global-scale information about families with LQTS is an important initiative to ensure diagnostic and management approaches are applicable to different populations and ethnicities. (Source: Journal of Arrhythmia)
Source: Journal of Arrhythmia - March 16, 2016 Category: Cardiology Source Type: research

The feasibility of a Box isolation strategy for non-paroxysmal atrial fibrillation in elderly patients
Conclusions Box isolation of non-PAF is effective and safe even in elderly patients. A prophylactic CTI ablation combined with Box isolation might be feasible to improve the long-term outcome. (Source: Journal of Arrhythmia)
Source: Journal of Arrhythmia - March 16, 2016 Category: Cardiology Source Type: research

Efficacy of atrial substrate modification based on dominant frequency of paroxysmal atrial fibrillation
Conclusions Atrial substrate ablation may improve the clinical outcome after ablation in patients after PVI with residual arrhythmia inducibility. (Source: Journal of Arrhythmia)
Source: Journal of Arrhythmia - March 14, 2016 Category: Cardiology Source Type: research

Anti-arrhythmic medications increase non-cardiac mortality – A meta-analysis of randomized control trials
Conclusion AAMs are associated with an increased risk of non-cardiac and all-cause mortality. The effect of AAMs, especially amiodarone, on non-cardiac mortality requires further evaluation. (Source: Journal of Arrhythmia)
Source: Journal of Arrhythmia - March 11, 2016 Category: Cardiology Source Type: research

The genetic background of arrhythmogenic right ventricular cardiomyopathy
Publication date: Available online 26 February 2016 Source:Journal of Arrhythmia Author(s): Seiko Ohno Arrhythmogenic right ventricular cardiomyopathy (ARVC) is characterized by degeneration of the right ventricle and ventricular tachycardia originating from the right ventricle. Additionally, the disease is an inherited cardiomyopathy that mainly follows the autosomal dominant pattern. More than 10 genes have been reported as causative genes for ARVC, and more than half of ARVC patients carry mutations in desmosome related genes. The desmosome is one of the structures involved in cell adhesion and its disruption lead...
Source: Journal of Arrhythmia - February 26, 2016 Category: Cardiology Source Type: research