Home monitoring report from a single lead Lumax DX implantable cardioverter defibrillator: New observations in a new system
Publication date: Available online 25 January 2016 Source:Journal of Arrhythmia Author(s): Yuval Konstantino, Alex Kleiman, Guy Amit A 56-year-old man underwent a single lead Lumax 640 DX implantable cardioverter defibrillator implantation for primary prevention of sudden cardiac death. A DX system consists of a single lead, which provides atrial as well as ventricular electrograms, and enhances atrial arrhythmia detection. Three months after the implantation, high-frequency episodes were detected on the far field and the atrial channels, but not on the bipolar right ventricular channel; these were classified as ...
Source: Journal of Arrhythmia - January 26, 2016 Category: Cardiology Source Type: research

Molecular pathogenesis of long QT syndrome type 2
Publication date: Available online 22 January 2016 Source:Journal of Arrhythmia Author(s): Jennifer L. Smith, Corey L. Anderson, Don E. Burgess, Claude S. Elayi, Craig T. January, Brian P. Delisle The molecular mechanisms underlying congenital long QT syndrome (LQTS) are now beginning to be understood. New insights into the etiology and therapeutic strategies are emerging from heterologous expression studies of LQTS-linked mutant proteins, as well as inducible pluripotent stem cell derived cardiomyocytes (iPSC-CMs) from LQTS patients. This review focuses on the major molecular mechanism that underlies LQTS ...
Source: Journal of Arrhythmia - January 23, 2016 Category: Cardiology Source Type: research

Letter to the Editor: Marino et al. Inappropriate mode switching clarified by using a chest radiograph
Publication date: Available online 19 January 2016 Source:Journal of Arrhythmia Author(s): Mohammad Ali Akbarzadeh (Source: Journal of Arrhythmia)
Source: Journal of Arrhythmia - January 20, 2016 Category: Cardiology Source Type: research

Management of antithrombotic therapy during cardiac implantable device surgery
Publication date: Available online 18 January 2016 Source:Journal of Arrhythmia Author(s): Ahmed AlTurki, Riccardo Proietti, David H. Birnie, Vidal Essebag Anticoagulants are commonly used drugs that are frequently encountered during device placement. Deciding when to halt or continue the use of anticoagulants is a balance between the risks of thromboembolism versus bleeding. Patients taking warfarin with a high risk of thromboembolism should continue to take their warfarin without interruption during device placement while ensuring their international normalized ratio remains below 3. For patients who are taki...
Source: Journal of Arrhythmia - January 18, 2016 Category: Cardiology Source Type: research

Post-marketing surveillance on the long-term use of dabigatran in Japanese patients with nonvalvular atrial fibrillation: Preliminary report of the J-dabigatran surveillance
Conclusions The interim findings from this 6148 patient PMS study further corroborate the favorable safety profile of dabigatran as demonstrated previously in controlled clinical trials. (ClinicalTrials.gov number, NCT01491178.) (Source: Journal of Arrhythmia)
Source: Journal of Arrhythmia - January 16, 2016 Category: Cardiology Source Type: research

Usefulness of combined CARTO electroanatomical mapping and manifest entrainment in ablating adenosine triphosphate-sensitive atrial tachycardia originating from the atrioventricular node vicinity
Conclusion CARTO mapping- and manifest entrainment-guided ablation strategy is effective and safe in the treatment of ATP-AT. (Source: Journal of Arrhythmia)
Source: Journal of Arrhythmia - January 14, 2016 Category: Cardiology Source Type: research

Arrhythmia management after device removal
Publication date: Available online 24 October 2015 Source:Journal of Arrhythmia Author(s): Nobuhiro Nishii Arrhythmic management is needed after removal of cardiac implantable electronic devices (CIEDs). Patients completely dependent on CIEDs need temporary device back-up until new CIEDs are implanted. Various methods are available for device back-up, and the appropriate management varies among patients. The duration from CIED removal to implantation of a new CIED also differs among patients. Temporary pacing is needed for patients with bradycardia, a wearable cardioverter defibrillator (WCD) or catheter ablation is ...
Source: Journal of Arrhythmia - January 11, 2016 Category: Cardiology Source Type: research

Autonomic and cardio-respiratory responses to exercise in Brugada Syndrome patients
Conclusion Thai BrS patients had a more rapid rate of restoration of the parasympathetic and smaller level of sympathetic activation after exercise. They had mild hyperkalemia which is reduced according to the exercise. Furthermore, they exhibited impaired cardio-respiratory fitness. (Source: Journal of Arrhythmia)
Source: Journal of Arrhythmia - January 11, 2016 Category: Cardiology Source Type: research

Pseudofusion in a dual chamber pacemaker: Is this pacemaker working properly?
Publication date: Available online 29 October 2015 Source:Journal of Arrhythmia Author(s): Mohammad Ali Akbarzadeh, Abolfath Alizadeh, Negar Bahrololoumi Bafruee (Source: Journal of Arrhythmia)
Source: Journal of Arrhythmia - January 11, 2016 Category: Cardiology Source Type: research

Left cardiac sympathetic denervation: An important treatment option for patients with hereditary ventricular arrhythmias
Publication date: Available online 29 October 2015 Source:Journal of Arrhythmia Author(s): Yongkeun Cho Medications such as ß-blockers are currently the primary treatment for patients with hereditary arrhythmia syndromes such as long QT syndrome (LQTS) and catecholaminergic polymorphic ventricular tachycardia (CPVT). However, these drugs are ineffective in some patients, and the other treatment option, that is implantable cardioverter defibrillator (ICD) implantation, is associated with significant complications in young and active patients. Left cardiac sympathetic denervation (LCSD) may reduce the wide gap between...
Source: Journal of Arrhythmia - January 11, 2016 Category: Cardiology Source Type: research

Measurement of diffuse ventricular fibrosis with myocardial T1 in patients with atrial fibrillation
Conclusion AF at the time of CMRI was associated with lower post-contrast ventricular T1 compared with sinus rhythm. This effect was at least partly due to elevated heart rate. T1 was not associated with the recurrence of AF after ablation. (Source: Journal of Arrhythmia)
Source: Journal of Arrhythmia - January 11, 2016 Category: Cardiology Source Type: research

Practical applicability of landiolol, an ultra-short-acting β1-selective blocker, for rapid atrial and ventricular tachyarrhythmias with left ventricular dysfunction
Conclusions Landiolol is effective in patients with heart failure not only due to rapid AF/AFL but also due to VTs. However, preserved LVEF is important for efficacy and safety in landiolol treatment. (Source: Journal of Arrhythmia)
Source: Journal of Arrhythmia - January 11, 2016 Category: Cardiology Source Type: research

Development of an alert system for subjects with paroxysmal atrial fibrillation
Conclusion This method of analysis of RR interval data shows potential use to alert a PAF subject before the onset of an AF episode. (Source: Journal of Arrhythmia)
Source: Journal of Arrhythmia - January 11, 2016 Category: Cardiology Source Type: research

Takotsubo syndrome and polymorphic ventricular tachycardia: The chicken or the egg
Publication date: Available online 3 November 2015 Source:Journal of Arrhythmia Author(s): John E. Madias (Source: Journal of Arrhythmia)
Source: Journal of Arrhythmia - January 11, 2016 Category: Cardiology Source Type: research

Incidence of cardiac implantable electronic device infections and migrations in Japan: Results from a 129 institute survey
Conclusions This survey was the first on CIED infection and migration in Japan. The CIED infection rate (1.12%) was similar to that previously reported. A high infection rate (2.77%) was observed in the infection experienced institutes. (Source: Journal of Arrhythmia)
Source: Journal of Arrhythmia - January 11, 2016 Category: Cardiology Source Type: research