Biological Treatment Approaches for Degenerative Disk Disease: A Literature Review of In Vivo Animal and Clinical Data
Conclusion Published clinical studies on cell therapy have reported encouraging results in the treatment of DDD and resultant back pain. We expect new data to emerge in the near future as treatments for DDD continue to evolve in parallel to our greater understanding of disk health and pathology.[...]Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents | Abstract | open access Full text (Source: Global Spine Journal)
Source: Global Spine Journal - January 27, 2016 Category: Orthopaedics Authors: Moriguchi, YuAlimi, MarjanKhair, ThaminaManolarakis, GeorgeBerlin, ConnorBonassar, Lawrence J.Härtl, Roger Tags: Review Article Source Type: research
The Effects of Smoking and Smoking Cessation on Spine Surgery: A Systematic Review of the Literature
Conclusion Smoking negatively affects both the objective and subjective outcomes of surgery in the lumbar and cervical spine. Current literature supports smoking cessation as an effective tool in potentially mitigating these unwanted outcomes. Future investigations in this field should be directed toward developing a better understanding of the complex relationship between smoking and poorer outcomes in spine surgery as well as developing more efficacious cessation strategies.[...]Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents | Abstract | open access Full text (Sou...
Source: Global Spine Journal - January 15, 2016 Category: Orthopaedics Authors: Jackson, Keith L.Devine, John G. Tags: Review Article Source Type: research
The Effects of Obesity on Spine Surgery: A Systematic Review of the Literature
Conclusion Obese individuals represent a unique patient population with respect to nonoperative treatment, postoperative complication rates, and functional outcomes. However, given the equivalent or greater treatment effect of surgery, this comorbidity should not prohibit obese patients from undergoing operative intervention. Future investigations in this area should attempt to develop strategies to minimize complications and improve outcomes in obese individuals and also examine the role of controlled weight loss preoperatively to mitigate these risks.[...]Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJ...
Source: Global Spine Journal - January 15, 2016 Category: Orthopaedics Authors: Jackson, Keith L.Devine, John G. Tags: Review Article Source Type: research
Change in Off-Label Use of Bone Morphogenetic Protein in Spine Surgery and Associations with Adverse Outcome
Conclusions Using a previously untapped data source, we show decreased (off-label) BMP-2 use in spinal fusions, particularly in cervical fusions. Although there was a tendency of decreased odds in 2009 to 2012, higher resource utilization and odds for complications remain in patients using BMP-2. A national registry or prospective observational studies will benefit the ongoing discussion.[...]Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents | Abstract | open access Full text (Source: Global Spine Journal)
Source: Global Spine Journal - January 15, 2016 Category: Orthopaedics Authors: Poeran, JashvantOpperer, MathiasRasul, RehanaMazumdar, MadhuGirardi, Federico P.Hughes, Alexander P.Memtsoudis, Stavros G.Vougioukas, Vassilios Tags: Original Article Source Type: research
Iliac Crest Bone Graft versus Local Autograft or Allograft for Lumbar Spinal Fusion: A Systematic Review
Conclusion In the lumbar spine, ICBG, local autograft, and allograft have similar effectiveness in terms of fusion rates, pain scores, and functional outcomes. However, ICBG is associated with an increased risk for donor site-related complications. Significant limitations exist in the available literature when comparing ICBG, local autograft, and allograft for lumbar fusion, and thus ICBG versus other fusion methods necessitates further investigation.[...]Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents | Abstract | open access Full text (Source: Global Spine Journal)
Source: Global Spine Journal - January 6, 2016 Category: Orthopaedics Authors: Tuchman, AlexanderBrodke, Darrel S.Youssef, Jim A.Meisel, Hans-JörgDettori, Joseph R.Park, Jong-BeomYoon, S. TimWang, Jeffrey C. Tags: Review Article Source Type: research
Postoperative Delayed Cervical Palsies: Understanding the Etiology
Conclusions Although this study partially supports a mechanical etiology in the pathogenesis of a DCP, we also describe a notable correlation with autoimmune risk factors. Bilateral and multimyotomal involvement provides additional support that some DCPs may result from an inflammatory response and thus an underlying multifactorial etiology for this complication.[...]Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents | Abstract | open access Full text (Source: Global Spine Journal)
Source: Global Spine Journal - January 5, 2016 Category: Orthopaedics Authors: Planchard, Ryan F.Maloney, Patrick R.Mallory, Grant W.Puffer, Ross C.Spinner, Robert J.Nassr, AhmadFogelson, Jeremy L.Krauss, William E.Clarke, Michelle J. Tags: Original Article Source Type: research
Return to Play in Athletes Receiving Cervical Surgery: A Systematic Review
Conclusions RTP decisions after cervical spine surgery remain controversial, and there is a paucity of existing literature on this topic. Successful return to competitive sports is well described after single-level anterior cervical diskectomy and fusion surgery for herniated disk. RTP outcomes involving other cervical spine diagnoses and surgical procedures remain unclear. Additional quality research is needed on this topic.[...]Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents | Abstract | open access Full text (Source: Global Spine Journal)
Source: Global Spine Journal - January 5, 2016 Category: Orthopaedics Authors: Molinari, Robert W.Pagarigan, KrystleDettori, Joseph R.Molinari, RobertDehaven, Kenneth E. Tags: EBSJ Special Section: Systematic Review Source Type: research
Success in Spine Care: The Proof Is in the Measurements, Part III
Global Spine JDOI: 10.1055/s-0035-1570461Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents | open access Full text (Source: Global Spine Journal)
Source: Global Spine Journal - January 5, 2016 Category: Orthopaedics Authors: Norvell, Daniel C.Dettori, Joseph R.Chapman, Jens R. Tags: EBSJ Special Section: Science in Spine Source Type: research
Management of Giant Calcified Thoracic Disks and Description of the Trench Vertebrectomy Technique
Conclusions GCTDs are difficult neurosurgical challenges owing to their size, degree of spinal cord compression, and consistency. We recommend a trench vertebrectomy via a thoracotomy in their surgical management. This procedure safely allows the identification of normal dura on either side of the compressed segment prior to performing a diskectomy. Excellent fusion rates were achieved with insertion of rib head autograft in the trench.[...]Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents | Abstract | open access Full text (Source: Global Spine Journal)
Source: Global Spine Journal - December 19, 2015 Category: Orthopaedics Authors: Al-Mahfoudh, RafidMitchell, Paul S.Wilby, MartinCrooks, DanielBarrett, ChrisPillay, RobinPigott, Tim Tags: Original Article Source Type: research
Adverse Event Recording and Reporting in Clinical Trials Comparing Lumbar Disc Replacement with Lumbar Fusion: a Systematic Review (Podcast)
Global Spine JDOI: 10.1055/s-0035-1570459Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents | open access Full text (Source: Global Spine Journal)
Source: Global Spine Journal - December 18, 2015 Category: Orthopaedics Source Type: research
Validation of a Russian Language Oswestry Disability Index Questionnaire
Conclusions The R-ODI is both valid and reliable for use among the Russian-speaking population in the United States.[...]Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents | Abstract | open access Full text (Source: Global Spine Journal)
Source: Global Spine Journal - December 15, 2015 Category: Orthopaedics Authors: Yu, Elizabeth M.Nosova, Emily V.Falkenstein, YuriPrasad, PriyaLeasure, Jeremi M.Kondrashov, Dimitriy G. Tags: Original Article Source Type: research
Relief of Cervicogenic Headaches after Single-Level and Multilevel Anterior Cervical Diskectomy: A 5-Year Post Hoc Analysis
Conclusion Both CDA and ACDF at either one or two levels are associated with sustained headache relief from baseline. Patients undergoing two-level arthroplasty had significantly greater improvement in headache at all points except for at 18 and 60 months. This difference in improvement was not observed in patients undergoing single-level arthroplasty. The mechanism of greater headache relief after two-level arthroplasty remains unclear.[...]Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents | Abstract | open access Full text (Source: Global Spine Journal)
Source: Global Spine Journal - December 15, 2015 Category: Orthopaedics Authors: Liu, Jonathan J.Cadena, GilbertPanchal, Ripul R.Schrot, Rudolph J.Kim, Kee D. Tags: Original Article Source Type: research
Perioperative Complications of Cervical Spine Surgery: Analysis of a Prospectively Gathered Database through the Association for Collaborative Spinal Research
Conclusions Perioperative complication rates in cervical spine surgery are significantly lower in younger patients, surgery performed through an anterior approach (compared with a posterior or combined approach), with fewer levels involved (particularly in posterior surgery), and in primary (compared with revision) procedures.[...]Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents | Abstract | open access Full text (Source: Global Spine Journal)
Source: Global Spine Journal - December 15, 2015 Category: Orthopaedics Authors: Leckie, StevenYoon, S. TimIsaacs, RobertRadcliff, KrisFessler, RichardHaid, RegisTraynelis, Vincent Tags: Original Article Source Type: research
Perioperative Complications of Pedicle Subtraction Osteotomy
Conclusion The major complication rate for pedicle subtraction osteotomy was 15% and the minor complication rate was 23%. The most common major complication was neurologic deficit in 6.2%. The complication rate did not change with increased surgeon experience.[...]Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents | Abstract | open access Full text (Source: Global Spine Journal)
Source: Global Spine Journal - December 15, 2015 Category: Orthopaedics Authors: Daubs, Michael D.Brodke, Darrel S.Annis, ProkopisLawrence, Brandon D. Tags: Original Article Source Type: research
Definition of levels of evidence (LoE) and overall strength of evidence (SoE)
Global Spine J 2015; 05: 539-539DOI: 10.1055/s-0035-1570346Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents | open access Full text (Source: Global Spine Journal)
Source: Global Spine Journal - December 7, 2015 Category: Orthopaedics Source Type: research
