Characterization of New Bone Morphogenetic Protein (Bmp) ‐2 Regulatory Alleles
This article is protected by copyright. All rights reserved. (Source: genesis)
Source: genesis - March 1, 2017 Category: Genetics & Stem Cells Authors: Tapan A. Shah, Youhua Zhu, Nadia N. Shaikh, Marie A. Harris, Stephen E. Harris, Melissa B. Rogers Tags: Research Article Source Type: research
Specific and spatial labeling of P0 ‐Cre versus Wnt1‐Cre in cranial neural crest in early mouse embryos
This article is protected by copyright. All rights reserved. (Source: genesis)
Source: genesis - March 1, 2017 Category: Genetics & Stem Cells Authors: Guiqian Chen, Mohamed Ishan, Jingwen Yang, Satoshi Kishigami, Tomokazu Fukuda, Greg Scott, Manas K. Ray, Chenming Sun, Shiyou Chen, Yoshihiro Komatsu, Mishina Yuji, Hong ‐Xiang Liu Tags: Research Article Source Type: research
Xenopus, an ideal model organism to study laterality in conjoined twins
Abstract
Conjoined twins occur at low frequency in all vertebrates including humans. Many twins fused at the chest or abdomen display a very peculiar laterality defect: while the left twin is normal with respect to asymmetric organ morphogenesis and placement (situs solitus), the organ situs is randomized in right twins. Although this phenomenon has fascinated already some of the founders of experimental embryology in the 19th and early 20th century, such as Dareste, Fol, Warynsky and Spemann, its embryological basis has remained enigmatic. Here we summarize historical experiments and interpretations as well as current mod...
Source: genesis - January 28, 2017 Category: Genetics & Stem Cells Authors: Matthias Tisler, Axel Schweickert, Martin Blum Tags: REVIEW Source Type: research
What we can learn from a tadpole about ciliopathies and airway diseases: Using systems biology in Xenopus to study cilia and mucociliary epithelia
Abstract
Over the past years, the Xenopus embryo has emerged as an incredibly useful model organism for studying the formation and function of cilia and ciliated epithelia in vivo. This has led to a variety of findings elucidating the molecular mechanisms of ciliated cell specification, basal body biogenesis, cilia assembly, and ciliary motility. These findings also revealed the deep functional conservation of signaling, transcriptional, post‐transcriptional, and protein networks employed in the formation and function of vertebrate ciliated cells. Therefore, Xenopus research can contribute crucial insights not only into ...
Source: genesis - January 28, 2017 Category: Genetics & Stem Cells Authors: Peter Walentek, Ian K. Quigley Tags: REVIEW Source Type: research
Frogs model man: In vivo thyroid hormone signaling during development
Abstract
Thyroid hormone (TH) signaling comprises TH transport across cell membranes, metabolism by deiodinases, and molecular mechanisms of gene regulation. Proper TH signaling is essential for normal perinatal development, most notably for neurogenesis and fetal growth. Knowledge of perinatal TH endocrinology needs improvement to provide better treatments for premature infants and endocrine diseases during gestation and to counteract effects of endocrine disrupting chemicals. Studies in amphibians have provided major insights to understand in vivo mechanisms of TH signaling. The frog model boasts dramatic TH‐dependent ...
Source: genesis - January 28, 2017 Category: Genetics & Stem Cells Authors: Laurent M. Sachs, Daniel R. Buchholz Tags: REVIEW Source Type: research
Probing the biology of cell boundary conditions through confinement of Xenopus cell ‐free cytoplasmic extracts
Abstract
Cell‐free cytoplasmic extracts prepared from Xenopus eggs and embryos have for decades provided a biochemical system with which to interrogate complex cell biological processes in vitro. Recently, the application of microfabrication and microfluidic strategies in biology has narrowed the gap between in vitro and in vivo studies by enabling formation of cell‐size compartments containing functional cytoplasm. These approaches provide numerous advantages over traditional biochemical experiments performed in a test tube. Most notably, the cell‐free cytoplasm is confined using a two‐ or three‐dimensional boun...
Source: genesis - January 28, 2017 Category: Genetics & Stem Cells Authors: Jessica G. Bermudez, Hui Chen, Lily C. Einstein, Matthew C. Good Tags: REVIEW Source Type: research
Issue Information
(Source: genesis)
Source: genesis - January 28, 2017 Category: Genetics & Stem Cells Tags: Issue Information Source Type: research
Nkx2.5 regulates Endothelin Converting Enzyme ‐1 during pharyngeal arch patterning
This article is protected by copyright. All rights reserved. (Source: genesis)
Source: genesis - January 19, 2017 Category: Genetics & Stem Cells Authors: Jennifer M. Ikl é, Andre L. P. Tavares, Marisol King, Hailei Ding, Sophie Colombo, Beth A. Firulli, Anthony B. Fiulli, Kimara L. Targoff, Deborah Yelon, David E. Clouthier Tags: Research Article Source Type: research
Genome ‐wide analysis of canonical Wnt target gene regulation in Xenopus tropicalis challenges β‐catenin paradigm
This article is protected by copyright. All rights reserved. (Source: genesis)
Source: genesis - January 16, 2017 Category: Genetics & Stem Cells Authors: Yukio Nakamura, Stefan Hoppler Tags: Review Source Type: research
Seeing the Future: Using Xenopus to Understand Eye Regeneration
This article is protected by copyright. All rights reserved. (Source: genesis)
Source: genesis - January 16, 2017 Category: Genetics & Stem Cells Authors: Ai ‐Sun Tseng Tags: Review Source Type: research
Xenopus as a model for studies in mechanical stress and cell division
This article is protected by copyright. All rights reserved. (Source: genesis)
Source: genesis - January 16, 2017 Category: Genetics & Stem Cells Authors: G.A. Stooke ‐Vaughan, L.A. Davidson, S. Woolner Tags: Review Source Type: research
A Frog's View of EphrinB Signaling
This article is protected by copyright. All rights reserved. (Source: genesis)
Source: genesis - January 16, 2017 Category: Genetics & Stem Cells Authors: Yoo ‐Seok Hwang, Ira O. Daar Tags: Review Source Type: research
Probing forebrain to hindbrain circuit functions in Xenopus
This article is protected by copyright. All rights reserved. (Source: genesis)
Source: genesis - January 16, 2017 Category: Genetics & Stem Cells Authors: Darcy B. Kelley, Taffeta M. Elliott, Ben J. Evans, Ian C. Hall, Elizabeth C. Leininger, Heather J. Rhodes, Ayako Yamaguchi, Erik Zornik Tags: Review Source Type: research
What we can learn from a tadpole about ciliopathies and airway diseases – Using systems biology in Xenopus to study cilia and mucociliary epithelia
This article is protected by copyright. All rights reserved. (Source: genesis)
Source: genesis - January 16, 2017 Category: Genetics & Stem Cells Authors: Peter Walentek, Ian K. Quigley Tags: Review Source Type: research
Xenopus egg extract to study regulation of genome ‐wide and locus‐specific DNA replication
This article is protected by copyright. All rights reserved. (Source: genesis)
Source: genesis - January 16, 2017 Category: Genetics & Stem Cells Authors: Erica Raspelli, Lucia Falbo, Vincenzo Costanzo Tags: Review Source Type: research
