Issue Information
(Source: genesis)
Source: genesis - May 22, 2017 Category: Genetics & Stem Cells Tags: Issue Information Source Type: research
IL ‐1β Inhibits Osteogenesis of Human Bone Marrow‐Derived Mesenchymal Stem Cells by Activating FoxD3/microRNA‐496 to Repress Wnt Signaling
This article is protected by copyright. All rights reserved. (Source: genesis)
Source: genesis - May 16, 2017 Category: Genetics & Stem Cells Authors: Jian Huang, Liang Chen Tags: Research Article Source Type: research
Genesis special issue: New models for arthropod research
(Source: genesis)
Source: genesis - May 9, 2017 Category: Genetics & Stem Cells Authors: Helena Araujo Tags: EDITORIAL Source Type: research
Generation of Nkx2 ‐5/CreER Transgenic Mice for Inducible Cre Expression in Developing Hearts
This article is protected by copyright. All rights reserved. (Source: genesis)
Source: genesis - May 1, 2017 Category: Genetics & Stem Cells Authors: Sara Ranjbarvaziri, Shuin Park, Ngoc B. Nguyen, William B. Gilmore, Peng Zhao, Reza Ardehali Tags: Technology Report Source Type: research
Rhodnius prolixus: From classical physiology to modern developmental biology
Abstract
The hemiptera Rhodnius prolixus is a blood‐feeding insect and a primary vector of Trypanosoma cruzi, the etiological agent of the Chagas disease. Over the past century, Rhodnius has been the subject of intense investigations, which have contributed to unveil important aspects of metabolism and physiology in insects. Recent technological innovations are helping dissect the genetic and molecular underpinnings of Rhodnius embryogenesis and organogenesis, thus fostering the use of this important species in the fields of developmental and evolutionary biology. Rhodnius represents also an excellent system to study dev...
Source: genesis - April 22, 2017 Category: Genetics & Stem Cells Authors: Rodrigo Nunes ‐da‐Fonseca, Mateus Berni, Vitória Tobias‐dos‐Santos, Attilio Pane, Helena Marcolla Araujo Tags: REVIEW Source Type: research
The honeybee as a model insect for developmental genetics
Abstract
Honeybees are an important component of modern agricultural systems, and a fascinating and scientifically engrossing insect. Honeybees are not commonly used as model systems for understanding development in insects despite their importance in agriculture. Honeybee embryogenesis, while being superficially similar to Drosophila, is molecularly very different, especially in axis formation and sex determination. In later development, much of honeybee biology is modified by caste development, an as yet poorly understood, but excellent, system to study developmental plasticity. In adult stages, developmental plasticity ...
Source: genesis - April 22, 2017 Category: Genetics & Stem Cells Authors: A.G. Cridge, M.R. Lovegrove, J.G. Skelly, S.E. Taylor, G.E.L. Petersen, R.C. Cameron, P.K. Dearden Tags: REVIEW Source Type: research
Oncopeltus fasciatus as an evo ‐devo research organism
Abstract
The large milkweed bug Oncopeltus fasciatus was one of the main study insects for a range of biological questions throughout much of the 20th century. Its importance waned with the introduction of Drosophila melanogaster as a genetic model organism. The evo‐devo revolution of the turn of the century re‐introduced Oncopeltus into the scientific community, and it has proved increasingly useful, mostly within a comparative context for evolution driven research. The last few years have seen a number of significant contributions to our understanding of the evolution of developmental processes in insects, and in art...
Source: genesis - April 22, 2017 Category: Genetics & Stem Cells Authors: Ariel D. Chipman Tags: REVIEW Source Type: research
Factors involved in early polarization of the anterior ‐posterior axis in the milkweed bug Oncopeltus fasciatus
Abstract
The axes of insect embryos are defined early in the blastoderm stage. Genes involved in this polarization are well known in Drosophila, but less so in other insects, such as the milkweed bug Oncopeltus fasciatus. Using quantitative PCR, we looked at differential expression of several candidate genes for early anterior‐posterior patterning and found that none of them are expressed asymmetrically in the early blastoderm. We then used an RNA‐Seq approach to identify novel candidate genes that might be involved in early polarization in Oncopeltus. We focused on transcription factors (TFs) as these are likely to be...
Source: genesis - April 22, 2017 Category: Genetics & Stem Cells Authors: Neta Ginzburg, Mira Cohen, Ariel D. Chipman Tags: RESEARCH ARTICLE Source Type: research
Molecular control of gut formation in the spider parasteatoda tepidariorum
Abstract
The development of a digestive system is an essential feature of bilaterians. Studies of the molecular control of gut formation in arthropods have been studied in detail in the fruit fly Drosophila melanogaster. However, little is known in other arthropods, especially in noninsect arthropods. To better understand the evolution of arthropod alimentary system, we investigate the molecular control of gut development in the spider Parasteatoda tepidariorum (Pt), the primary chelicerate model species for developmental studies. Orthologs of the ectodermal genes Pt‐wingless (Pt‐wg) and Pt‐hedgehog (Pt‐hh), of the...
Source: genesis - April 22, 2017 Category: Genetics & Stem Cells Authors: Nat ália Martins Feitosa, Matthias Pechmann, Evelyn E. Schwager, Vitória Tobias‐Santos, Alistair P. McGregor, Wim G. M. Damen, Rodrigo Nunes da Fonseca Tags: RESEARCH ARTICLE Source Type: research
Ploidy has little effect on timing early embryonic events in the haplo ‐diploid wasp Nasonia
In this study, we set out to understand how the obligate difference in ploidy in the haplodiploid wasp, Nasonia, affects the MZT and which aspects of the Drosophila MZT are conserved. While subtle differences in early embryonic development were observed in comparisons among haploid, diploid, and triploid embryos, in all cases embryos cellularize at cell cycle 12. When ZGA was inhibited, both diploid female, and haploid male, embryos went through 12 syncytial divisions and failed to cellularize before dying without further divisions. We also found that key players of the Drosophila MZT are conserved in Nasonia but have nove...
Source: genesis - April 22, 2017 Category: Genetics & Stem Cells Authors: Deanna Arsala, Jeremy A. Lynch Tags: RESEARCH ARTICLE Source Type: research
Issue Information
(Source: genesis)
Source: genesis - April 18, 2017 Category: Genetics & Stem Cells Tags: Issue Information Source Type: research
Golga5 is dispensable for mouse embryonic development and postnatal survival
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Source: genesis - April 1, 2017 Category: Genetics & Stem Cells Authors: Lynessa J. McGee, Alex L. Jiang, Yu Lan Tags: Letter Source Type: research
Generation and Characterization of a Conditional Allele of Interferon regulatory factor 6
This article is protected by copyright. All rights reserved. (Source: genesis)
Source: genesis - April 1, 2017 Category: Genetics & Stem Cells Authors: Arianna L. Smith, Youssef A. Kousa, Akira Kinoshita, Kate Fodor, Baoli Yang, Brian C. Schutte Tags: Technology Report Source Type: research
Short Hairpin RNA is More Effective than Long Hairpin RNA in Eliciting pointed Loss ‐Of‐Function Phenotypes in Drosophila
This article is protected by copyright. All rights reserved. (Source: genesis)
Source: genesis - April 1, 2017 Category: Genetics & Stem Cells Authors: Rosa Bartoletti, Benjamin Capozzoli, Joneisha Moore, Jaynie Moran, Brandy Shrawder, Pavithra Vivekanand Tags: Letter Source Type: research
Issue Information
(Source: genesis)
Source: genesis - March 23, 2017 Category: Genetics & Stem Cells Tags: Issue Information Source Type: research
