MicroRNAs regulate synaptic plasticity underlying drug addiction
Genes, Brain and Behavior, EarlyView. (Source: Genes, Brain and Behavior)
Source: Genes, Brain and Behavior - October 10, 2017 Category: Genetics & Stem Cells Source Type: research
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Genes, Brain and Behavior, Ahead of Print. (Source: Genes, Brain and Behavior)
Source: Genes, Brain and Behavior - October 10, 2017 Category: Genetics & Stem Cells Source Type: research
Epigenetics at the crossroads between genes, environment and resilience in anxiety disorders
Genes, Brain and Behavior, EarlyView. (Source: Genes, Brain and Behavior)
Source: Genes, Brain and Behavior - September 26, 2017 Category: Genetics & Stem Cells Source Type: research
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Genes, Brain and Behavior, Ahead of Print. (Source: Genes, Brain and Behavior)
Source: Genes, Brain and Behavior - September 26, 2017 Category: Genetics & Stem Cells Source Type: research
Increased fear learning, spatial learning as well as neophobia in Rgs2 −/− mice
Genes, Brain and Behavior, EarlyView. (Source: Genes, Brain and Behavior)
Source: Genes, Brain and Behavior - September 22, 2017 Category: Genetics & Stem Cells Source Type: research
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Genes, Brain and Behavior, Ahead of Print. (Source: Genes, Brain and Behavior)
Source: Genes, Brain and Behavior - September 22, 2017 Category: Genetics & Stem Cells Source Type: research
Dopaminergic and behavioural changes in a loss ‐of‐imprinting model of Cdkn1c
The imprinted gene Cdkn1c is expressed exclusively from the maternally inherited allele as a consequences of epigenetic regulation. Cdkn1c exemplifies many of the functional characteristics of imprinted genes, playing a role in foetal growth and placental development. However, Cdkn1c also plays an important role in the brain, being key to the appropriate proliferation and differentiation of midbrain dopaminergic neurons. Using a transgenic model (Cdkn1cBACx1) with a twofold elevation in Cdkn1c expression that mimics loss‐of‐imprinting, we show that increased expression of Cdkn1c in the brain gives rise to neurobiologic...
Source: Genes, Brain and Behavior - September 15, 2017 Category: Genetics & Stem Cells Authors: G. I. McNamara, B. A. Davis, M. Browne, T. Humby, J. W. Dalley, J. Xia, R. M. John, A. R. Isles Tags: Original Article Source Type: research
The mushroom body D1 dopamine receptor controls innate courtship drive
Genes, Brain and Behavior,Volume 17, Issue 2, Page 158-167, February 2018. (Source: Genes, Brain and Behavior)
Source: Genes, Brain and Behavior - September 13, 2017 Category: Genetics & Stem Cells Source Type: research
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Genes, Brain and Behavior,Volume 17, Issue 2, Page 158-167, February 2018. (Source: Genes, Brain and Behavior)
Source: Genes, Brain and Behavior - September 13, 2017 Category: Genetics & Stem Cells Source Type: research
Issue Information
(Source: Genes, Brain and Behavior)
Source: Genes, Brain and Behavior - September 12, 2017 Category: Genetics & Stem Cells Tags: Issue Information Source Type: research
Epigenetic germline inheritance in mammals: looking to the past to understand the future
Genes, Brain and Behavior, EarlyView. (Source: Genes, Brain and Behavior)
Source: Genes, Brain and Behavior - September 6, 2017 Category: Genetics & Stem Cells Source Type: research
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Genes, Brain and Behavior, Ahead of Print. (Source: Genes, Brain and Behavior)
Source: Genes, Brain and Behavior - September 6, 2017 Category: Genetics & Stem Cells Source Type: research
Epigenetics at the crossroads between genes, environment and resilience in anxiety disorders
The pathogenesis of anxiety disorders is multifactorial, involving complex interactions between biological factors, environmental influences, and psychological mechanisms. Recent advances have highlighted the role of epigenetics in bridging the gap between multiple contributing risk factors towards an increased understanding of the pathomechanisms underlying anxiety. In this review, we present an overview of the current state of knowledge regarding putative risk mechanisms in the pathogenesis of anxiety disorders, placing a particular focus on the role of protective factors serving to buffer a risk factor constellation and...
Source: Genes, Brain and Behavior - September 5, 2017 Category: Genetics & Stem Cells Authors: M. A. Schiele, K. Domschke Tags: Review Source Type: research
Prenatal cocaine exposure disrupts the dopaminergic system and its postnatal responses to cocaine
Impaired attention is the hallmark consequence of prenatal cocaine exposure (PCE), affecting brain development, learning, memory and social adaptation starting at an early age. To date, little is known about the brain structures and neurochemical processes involved in this effect. Through focusing on the visual system and employing zebrafish as a model, we show that PCE reduces expression of dopamine receptor Drd1, with levels reduced in the optic tectum and other brain regions, except the telencephalon. Organism‐wide, PCE results in a 1.7‐fold reduction in the expression of the dopamine transporter (dat), at baseline....
Source: Genes, Brain and Behavior - September 1, 2017 Category: Genetics & Stem Cells Authors: Elizabeth Riley, Valerie Maymi, Stephanie Pawlyszyn, Yu Lili, Irina V. Zhdanova Tags: ORIGINAL ARTICLE Source Type: research
Atp1a3 deficient heterozygous mice show lower rank in the hierarchy and altered social behavior
Atp1a3 is the Na‐pump alpha3 subunit gene expressed mainly in neurons of the brain. Atp1a3 deficient heterozygous mice (Atp1a3+/‐) show altered neurotransmission and deficits of motor function after stress loading. To understand the function of Atp1a3 in a social hierarchy, we evaluated social behaviors (social interaction, aggression, social approach, and social dominance) of Atp1a3+/‐ and compared the rank and hierarchy structure between Atp1a3+/‐ and wild‐type mice within a housing cage using the round‐robin tube test and barbering observations. Formation of a hierarchy decreases social conflict and promote ...
Source: Genes, Brain and Behavior - September 1, 2017 Category: Genetics & Stem Cells Authors: Hiroki Sugimoto, Keiko Ikeda, Kiyoshi Kawakami Tags: Original Article Source Type: research
