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Genes, Brain and Behavior, Ahead of Print. (Source: Genes, Brain and Behavior)
Source: Genes, Brain and Behavior - February 15, 2018 Category: Genetics & Stem Cells Source Type: research
Domperidone upregulates dopamine receptor expression and stimulates locomotor activity in larval zebrafish (Danio rerio)
The objectives of this study were to (1) quantify the temporal expression of transcripts (DA receptors, transporters and tyrosine hydroxylase) associated with DA signaling during early stages of zebrafish development and (2) determine their expression profiles following treatment with a D2 receptor antagonist domperidone (DMP). We also assessed locomotor behavior following treatment with DMP using alternating periods of light and dark (ie, dark photokinesis), as DA plays a key role in behavior. Relative expression levels of transcripts that were investigated and related to the DA system were detected after the first 24 h...
Source: Genes, Brain and Behavior - February 15, 2018 Category: Genetics & Stem Cells Authors: E. C. Shontz, C. L. Souders, J. T. Schmidt, C. J. Martyniuk Tags: ORIGINAL ARTICLE Source Type: research
Autophosphorylation of αCaMKII affects social interactions in mice
Genes, Brain and Behavior, EarlyView. (Source: Genes, Brain and Behavior)
Source: Genes, Brain and Behavior - February 14, 2018 Category: Genetics & Stem Cells Source Type: research
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Genes, Brain and Behavior, Ahead of Print. (Source: Genes, Brain and Behavior)
Source: Genes, Brain and Behavior - February 14, 2018 Category: Genetics & Stem Cells Source Type: research
P2Y12 deficiency in mouse impairs noradrenergic system in brain, and alters anxiety ‐like neurobehavior and memory
Genes, Brain and Behavior, EarlyView. (Source: Genes, Brain and Behavior)
Source: Genes, Brain and Behavior - February 9, 2018 Category: Genetics & Stem Cells Authors: F. Zheng,
Q. Zhou,
Y. Cao,
H. Shi,
H. Wu,
B. Zhang,
F. Huang,
X. Wu Source Type: research
Npas4 deficiency interacts with adolescent stress to disrupt prefrontal GABAergic maturation and adult cognitive flexibility
Genes, Brain and Behavior, EarlyView. (Source: Genes, Brain and Behavior)
Source: Genes, Brain and Behavior - February 9, 2018 Category: Genetics & Stem Cells Source Type: research
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Genes, Brain and Behavior, Ahead of Print. (Source: Genes, Brain and Behavior)
Source: Genes, Brain and Behavior - February 9, 2018 Category: Genetics & Stem Cells Source Type: research
Novelty ‐related behavior of young and adult DAT‐KO rats: implication for cognitive and emotional phenotypic patterns
In conclusion, DAT‐KO rats may show inattention while more novelty‐seeking traits appear in DAT‐HET rats. (Source: Genes, Brain and Behavior)
Source: Genes, Brain and Behavior - February 6, 2018 Category: Genetics & Stem Cells Authors: Annalisa Adinolfi, Cristiana Carbone, Damiana Leo, Raul R. Gainetdinov, Giovanni Laviola, Walter Adriani Tags: ORIGINAL ARTICLE Source Type: research
Post ‐GWAS in Psychiatric Genetics: A Developmental Perspective on the “Other” Next Steps
Genes, Brain and Behavior, EarlyView. (Source: Genes, Brain and Behavior)
Source: Genes, Brain and Behavior - February 5, 2018 Category: Genetics & Stem Cells Source Type: research
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Genes, Brain and Behavior, Ahead of Print. (Source: Genes, Brain and Behavior)
Source: Genes, Brain and Behavior - February 5, 2018 Category: Genetics & Stem Cells Source Type: research
Tay bridge and ERK activity are required for motoneuron function in the Drosophila neural system
Extracellular regulated kinase (Erk) activity is required during neural development for the specification of cell fates in neuroblasts and neuronal lineages, and also regulates several aspects of the activity and survival of mature neurons. The activation of Erk is regulated at multiple levels by kinases and phosphatases that alter its phosphorylation state and by other proteins that regulate its subcellular localization. Here we find that tay bridge (tay), a negative regulator of Erk in Drosophila imaginal discs, is required in the motoneurons to regulate the number and size of neuromuscular synapses in these cells. The e...
Source: Genes, Brain and Behavior - February 1, 2018 Category: Genetics & Stem Cells Authors: Cristina Molnar, Beatriz Estrada, Jose F. de Celis Tags: ORIGINAL ARTICLE Source Type: research
Novel mutations and phenotypes of epilepsy ‐associated genes in epileptic encephalopathies
Genes, Brain and Behavior, EarlyView. (Source: Genes, Brain and Behavior)
Source: Genes, Brain and Behavior - January 26, 2018 Category: Genetics & Stem Cells Authors: P. Zhou,
N. He,
J. ‐W. Zhang,
Z.‐J. Lin,
J. Wang,
L.‐M. Yan,
H. Meng,
B. Tang,
B.‐M. Li,
X.‐R. Liu,
Y.‐W. Shi,
Q.‐X. Zhai,
Y.‐H. Yi,
W.‐P. Liao Source Type: research
