Guidelines for Authors
(Source: Current Problems in Cardiology)
Source: Current Problems in Cardiology - November 24, 2017 Category: Cardiology Source Type: research

Aortic Valve Regurgitation: A Comprehensive Review
Aortic regurgitation (AR) has an estimated prevalence of 4.9% in the Framingham study, with moderate or severe AR occurring in 0.5% of the study population. The incidence and severity of AR increases with age, and may occur acutely or as a chronic valvular disease with distinct presentations, natural history and management strategy. Our review is a comprehensive description of the varied presentation of aortic regurgitation and its management. (Source: Current Problems in Cardiology)
Source: Current Problems in Cardiology - November 1, 2017 Category: Cardiology Authors: Oluwaseun A. Akinseye, Aradhana Pathak, Uzoma N. Ibebuogu Source Type: research

Foreword
Deposits of an abnormal protein (amyloid) in cardiac tissue is associated with the development of heart failure first with preserved systolic function and in end stages with heart failure and reduced ejection fraction. Although there have been important advances in the utilization of cardiac imaging and laboratory techniques that have made the diagnosis of cardiac amyloid more commonly, most of the patients are diagnosed in late stages and the prognosis of these patients is poor. (Source: Current Problems in Cardiology)
Source: Current Problems in Cardiology - November 1, 2017 Category: Cardiology Source Type: research

Aortic Valve Regurgitation: A Comprehensive Review
Aortic regurgitation (AR) is the diastolic reversal of blood flow from the aorta into the left ventricle. AR can be due to a primary disease of the aortic valve (AV) or abnormalities of the perivalvular apparatus and structures such as the aortic root and ascending aorta. The prevalence of AR was estimated as 4.9% in the Framingham study, with moderate and severe AR occurring in 0.5% of the study population.1 AR was also observed in 13% of men and 8.5% of women.2 The incidence and severity of AR increases with age, peaking at 40 –60 years. (Source: Current Problems in Cardiology)
Source: Current Problems in Cardiology - November 1, 2017 Category: Cardiology Authors: Oluwaseun A. Akinseye, Aradhana Pathak, Uzoma N. Ibebuogu Source Type: research

Current Trends and Future Perspectives in the Treatment of Pulmonary Arterial Hypertension
Pulmonary hypertension continues to be a life-threatening illness with debilitating physical and emotional consequences affecting around 1% of global population. The progression of this devastating disease is characterized by increase in pulmonary vascular resistance resulting in elevated pulmonary pressure, eventually leading to right heart failure and death. Better understanding of pathophysiology has led to substantial improvements in terms of availability of treatment options. The purpose of this review is to summarize the currently available treatment options along with pertinent trials and possible future therapies o...
Source: Current Problems in Cardiology - October 31, 2017 Category: Cardiology Authors: Sukhdeep Bhogal, Debabrata Mukherjee, Subhash Banerjee, Walter Tan, Timir K. Paul Source Type: research

Current Trends and Future Perspectives in the Treatment of Pulmonary Hypertension: WHO Group II-V
Pulmonary hypertension continues to be a life-threatening illness with debilitating physical and emotional consequences affecting around 1% of global population. The progression of this devastating disease is characterized by increase in pulmonary vascular resistance resulting in elevated pulmonary pressure, eventually leading to right heart failure and death. Better understanding of pathophysiology has led to substantial improvements in terms of availability of treatment options. The purpose of this review is to summarize the currently available treatment options along with pertinent trials and possible future therapies o...
Source: Current Problems in Cardiology - October 31, 2017 Category: Cardiology Authors: Sukhdeep Bhogal, Debabrata Mukherjee, Subhash Banerjee, AKM Monwarul Islam, Ramesh Daggubati, Timir K. Paul Source Type: research

Pregnancy and Heart Disease: Pregnancy-Associated Hypertension and Peripartum Cardiomyopathy
Cardiovascular diseases are major complications in pregnancy worldwide and the number of patients who develop cardiac problems during pregnancy is increasing. Pregnancy-associated hypertensive complications such as pre-eclampsia (PE) or peripartum cardiomyopathy (PPCM) are potentially life-threatening heart diseases emerging during pregnancy, under delivery or in the first postpartal months in previously healthy women. Both disease entities display substantial morbidity and mortality in the acute phase. (Source: Current Problems in Cardiology)
Source: Current Problems in Cardiology - October 31, 2017 Category: Cardiology Authors: Tobias Jonathan Pfeffer, Denise Hilfiker-Kleiner Source Type: research

Current Trends and Future Perspectives in the Treatment of Pulmonary Hypertension: WHO Group II-V
Pulmonary hypertension continues to be a life-threatening illness with debilitating physical and emotional consequences affecting around 1% of global population. The progression of this devastating disease is characterized by increase in pulmonary vascular resistance resulting in elevated pulmonary pressure, eventually leading to right heart failure and death. Better understanding of pathophysiology has led to substantial improvements in terms of availability of treatment options. The purpose of this review is to summarize the currently available treatment options along with pertinent trials and possible future therapies o...
Source: Current Problems in Cardiology - October 31, 2017 Category: Cardiology Authors: Sukhdeep Bhogal, Debabrata Mukherjee, Subhash Banerjee, AKM Monwarul Islam, Ramesh Daggubati, Timir K. Paul Source Type: research

Current Trends and Future Perspectives in the Treatment of Pulmonary Arterial Hypertension
Pulmonary hypertension continues to be a life-threatening illness with debilitating physical and emotional consequences affecting around 1% of global population. The progression of this devastating disease is characterized by increase in pulmonary vascular resistance resulting in elevated pulmonary pressure, eventually leading to right heart failure and death. Better understanding of pathophysiology has led to substantial improvements in terms of availability of treatment options. The purpose of this review is to summarize the currently available treatment options along with pertinent trials and possible future therapies o...
Source: Current Problems in Cardiology - October 31, 2017 Category: Cardiology Authors: Sukhdeep Bhogal, Carl J. Lavie, Ramesh Daggubati, Jennifer Treece, Ola Khairasa, Hector Ventura, Timir K. Paul Source Type: research

Current Trends and Future Perspectives in the Treatment of Pulmonary Hypertension: WHO Group II -V
Pulmonary hypertension continues to be a life-threatening illness with debilitating physical and emotional consequences affecting around 1% of global population. The progression of this devastating disease is characterized by increase in pulmonary vascular resistance resulting in elevated pulmonary pressure, eventually leading to right heart failure and death. Better understanding of pathophysiology has led to substantial improvements in terms of availability of treatment options. The purpose of this review is to summarize the currently available treatment options along with pertinent trials and possible future therapies o...
Source: Current Problems in Cardiology - October 31, 2017 Category: Cardiology Authors: Sukhdeep Bhogal, Debabrata Mukherjee, Subhash Banerjee, Monwarul Islam, Ramesh Daggubati, Timir K. Paul Source Type: research

Pregnancy and Heart Disease: Pregnancy-associated hypertension and peripartum cardiomyopathy
Cardiovascular diseases (CVD) are major complications in pregnancy worldwide and the number of patients who develop cardiac problems during pregnancy is increasing. Pregnancy associated hypertensive complications such as preeclampsia or peripartum cardiomyopathy (PPCM) are potentially life-threatening heart diseases emerging during pregnancy, under delivery or in the first postpartal months in previously healthy women. Both disease entities display substantial morbidity and mortality in the acute phase. (Source: Current Problems in Cardiology)
Source: Current Problems in Cardiology - October 31, 2017 Category: Cardiology Authors: Tobias Jonathan Pfeffer, Denise Hilfiker-Kleiner Source Type: research

Editorial Board
(Source: Current Problems in Cardiology)
Source: Current Problems in Cardiology - October 28, 2017 Category: Cardiology Source Type: research

Title Page
(Source: Current Problems in Cardiology)
Source: Current Problems in Cardiology - October 28, 2017 Category: Cardiology Source Type: research

Information for Readers
(Source: Current Problems in Cardiology)
Source: Current Problems in Cardiology - October 28, 2017 Category: Cardiology Source Type: research

Table of Contents
(Source: Current Problems in Cardiology)
Source: Current Problems in Cardiology - October 28, 2017 Category: Cardiology Source Type: research