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(Source: Computerized Medical Imaging and Graphics)
Source: Computerized Medical Imaging and Graphics - August 19, 2014 Category: Radiology Source Type: research

Spectral clustering applied for dynamic contrast-enhanced MR analysis of time–intensity curves
Magnetic resonance imaging (MRI) has become a reference technique for the diagnosis and staging of several types of cancer, including prostate, breast, and liver tumors. The typical multiparametric MRI protocol involves morphologic acquisition of T1-weighted (T1W) and/or T2-weighted (T2W) images as well as functional imaging using diffusion, spectroscopy, and perfusion sequences. Indeed, perfusion or dynamic contrast enhanced (DCE) imaging, which is acquired following injection of a contrast agent, is commonly employed to enhance the characterization of early cancers prior to therapy and to monitor their progression during...
Source: Computerized Medical Imaging and Graphics - August 12, 2014 Category: Radiology Authors: Guillaume Tartare, Denis Hamad, Mustapha Azahaf, Philippe Puech, Nacim Betrouni Source Type: research

Spectral Clustering Applied for Dynamic Contrast-Enhanced MR Analysis of Time-Intensity Curves
Magnetic resonance imaging (MRI) has become a reference technique for the diagnosis and staging of several types of cancer, including prostate, breast, and liver tumors. The typical multiparametric MRI protocol involves morphologic acquisition of T1-weighted (T1W) and/or T2-weighted (T2W) images as well as functional imaging using diffusion, spectroscopy, and perfusion sequences. Indeed, perfusion or dynamic contrast enhanced (DCE) imaging, which is acquired following injection of a contrast agent, is commonly employed to enhance the characterization of early cancers prior to therapy and to monitor their progression during...
Source: Computerized Medical Imaging and Graphics - August 12, 2014 Category: Radiology Authors: Guillaume Tartare, Denis Hamad, Mustapha Azahaf, Philippe Puech, Nacim Betrouni Source Type: research

A novel method for dendritic spines detection based on directional morphological filter and shortest path
Dendritic spines are tiny membranous protrusions from neuron's dendrites. They play a very important role in the nervous system. A number of mental diseases such as Alzheimer's disease and mental retardation are revealed to have close relations with spine morphologies or spine number changes. Spines have various shapes, and spine images are often not of good quality; hence it is very challenging to detect spines in neuron images. This paper presents a novel pipeline to detect dendritic spines in 2D maximum intensity projection (MIP) images and a new dendrite backbone extraction method is developed in the pipeline. (Source:...
Source: Computerized Medical Imaging and Graphics - August 7, 2014 Category: Radiology Authors: Ran Su, Changming Sun, Chao Zhang, Tuan D. Pham Source Type: research

Semi-automatic segmentation for 3D motion analysis of the tongue with dynamic MRI
The tongue is a crucial part of the oral cavity. Its behavior is critical for the production of speech, where its deformation shapes the vocal tract to produce sounds. It is also essential for eating, where it contains and propels the bolus during chewing and swallowing. Finally, the tongue is vital for breathing where every inhalation is accompanied by muscle activity designed to prevent the tongue from being pulled backward and closing off the airway [1]. (Source: Computerized Medical Imaging and Graphics)
Source: Computerized Medical Imaging and Graphics - August 1, 2014 Category: Radiology Authors: Junghoon Lee, Jonghye Woo, Fangxu Xing, Emi Z. Murano, Maureen Stone, Jerry L. Prince Source Type: research

Semi-automatic segmentation for 3D motion analysis of the tongue with dynamic MRI
Dynamic MRI has been widely used to track the motion of the tongue and measure its internal deformation during speech and swallowing. Accurate segmentation of the tongue is a prerequisite step to define the target boundary and constrain the tracking to tissue points within the tongue. Segmentation of 2D slices or 3D volumes is challenging because of the large number of slices and time frames involved in the segmentation, as well as the incorporation of numerous local deformations that occur throughout the tongue during motion. (Source: Computerized Medical Imaging and Graphics)
Source: Computerized Medical Imaging and Graphics - August 1, 2014 Category: Radiology Authors: Junghoon Lee, Jonghye Woo, Fangxu Xing, Emi Z. Murano, Maureen Stone, Jerry L. Prince Source Type: research

An image processing approach to analyze morphological features of microscopic images of muscle fibers
Skeletal muscle is the most abundant tissue of the human body, occupying about half of the body weight in healthy adults [1]. Skeletal muscle is principally composed of individual muscle fibers (or muscle cells) that are arranged in a structured manner. Muscle fibers are formed in the development process from the fusion of myoblasts (primitive muscle cells that can potentially develop into a muscle fiber) in a process known as myogenesis. The long, cylindrical, multinucleated muscle fibers is the biggest cell in the body, generally of tens of micrometers in diameter and hundreds of micrometer in length. (Source: Computeriz...
Source: Computerized Medical Imaging and Graphics - July 30, 2014 Category: Radiology Authors: Cesar Henrique Comin, Xiaoyin Xu, Yaming Wang, Luciano da Fontoura Costa, Zhong Yang Source Type: research

Detection of temporal lobe epilepsy using support vector machines in multi-parametric quantitative MR imaging
Magnetic resonance imaging (MRI) is a powerful tool for the evaluation of patients with brain disorders and neurological diseases. For those with temporal lobe epilepsy (TLE), the most common type of epilepsy in adults [1], it is the entry point to a clinical workflow that may conclude with temporal lobe surgery and an improved quality of life. Finding evidence of seizures on MRI is a clear diagnostic element for TLE, however this task is not easy given that epileptogenic lesions are often small and can be missed, they can be uncertain due to subtle intensity changes, or only perceptible after image post-processing. (Sourc...
Source: Computerized Medical Imaging and Graphics - July 21, 2014 Category: Radiology Authors: Diego Cantor-Rivera, Ali R. Khan, Maged Goubran, Seyed M. Mirsattari, Terry M. Peters Source Type: research

An effective and robust method for modeling multi-furcation liver vessel by using Gap Border Pairing
Highlights: Abstract: Shape-based 3D surface reconstructing methods for liver vessels have difficulties to tackle with limited contrast of medical images and the intrinsic complexity of multi-furcation parts. In this paper, we propose an effective and robust technique, called Gap Border Pairing (GBPa), to reconstruct surface of liver vessels with complicated multi-furcations. The proposed method starts from a tree-like skeleton which is extracted from segmented liver vessel volumes and preprocessed as a number of simplified smooth branching lines. Secondly, for each center point of any branching line, an optimized elliptic...
Source: Computerized Medical Imaging and Graphics - July 21, 2014 Category: Radiology Authors: Bin Fang, Nanchang Zhong, Yi Wang, Yuan Yan Tang, Shenhai Zheng, Zekun Li, Jia-hong Dong, Shao-xiang Zhang Tags: CT/MRI/PET Source Type: research

A pre-operative CT and non-contrast-enhanced C-arm CT registration framework for trans-catheter aortic valve implantation
Aortic valve disease is the most frequent valvular disease in western countries. According to a population-based study [1], 1.8% of the global population is affected by the disease. Compared to the well established open-chest valve surgery, minimal invasive trans-catheter aortic valve implantation (TAVI) is an emerging technique that is especially suitable for non-operable and high-risk surgical candidates with a severe aortic stenosis. Furthermore, it has the potential to replace the open heart surgery for regular risk patients. (Source: Computerized Medical Imaging and Graphics)
Source: Computerized Medical Imaging and Graphics - July 19, 2014 Category: Radiology Authors: Yongning Lu, Ying Sun, Rui Liao, Sim Heng Ong Source Type: research

A Pre-operative CT and Non-contrast-enhanced C-arm CT Registration Framework for Trans-catheter Aortic Valve Implantation
Aortic valve disease is the most frequent valvular disease in western countries. According to a population-based study [1], 1.8% of the global population is affected by the disease. Compared to the well established open-chest valve surgery, minimal invasive trans-catheter aortic valve implantation (TAVI) is an emerging technique that is especially suitable for non-operable and high-risk surgical candidates with a severe aortic stenosis. Furthermore, it has the potential to replace the open heart surgery for regular risk patients. (Source: Computerized Medical Imaging and Graphics)
Source: Computerized Medical Imaging and Graphics - July 19, 2014 Category: Radiology Authors: Yongning Lu, Ying Sun, Rui Liao, Sim Heng Ong Source Type: research

Fractional anisotropy asymmetry and the side of seizure origin for partial onset-temporal lobe epilepsy
In this study, FAA analysis is applied to 30 patients of partial TLE (15 left, 15 right) and 14 matched normal controls. Specifically, after registering all the images with the JHU-DTI-MNI template the average FA value of each FA skeleton section is calculated using the tract-based spatial statistics (TBSS) method. Then, FAA is calculated to quantify the WM diffusivity asymmetry of the corresponding region-pairs between the left and right hemispheres. Using FAA the regional asymmetry contributing significantly to the group differences of controls and left/right TLE, as well as the left and right TLE, is identified. As a co...
Source: Computerized Medical Imaging and Graphics - July 17, 2014 Category: Radiology Authors: Hai Li, Zhong Xue, Mario F. Dulay, Amit Verma, Christof Karmonik, Robert G. Grossman, Stephen T. Wong Tags: CT/MRI/PET Source Type: research