Adaptive-weighted bilateral filtering and other pre-processing techniques for optical coherence tomography
Highlights: Abstract: This paper presents novel pre-processing image enhancement algorithms for retinal optical coherence tomography (OCT). These images contain a large amount of speckle causing them to be grainy and of very low contrast. To make these images valuable for clinical interpretation, we propose a novel method to remove speckle, while preserving useful information contained in each retinal layer. The process starts with multi-scale despeckling based on a dual-tree complex wavelet transform (DT-CWT). We further enhance the OCT image through a smoothing process that uses a novel adaptive-weighted bilateral filter...
Source: Computerized Medical Imaging and Graphics - July 16, 2014 Category: Radiology Authors: N. Anantrasirichai, Lindsay Nicholson, James E. Morgan, Irina Erchova, Katie Mortlock, Rachel V. North, Julie Albon, Alin Achim Tags: Optical Imaging/Microscopy Source Type: research

A two-layer structure prediction framework for microscopy cell detection
With the development of bioimage informatics, there has been an increasing focus on the cell detection studies, which come over the problem of the traditional microscopy studies that only a few cells are detected, providing a more powerful statistical tool for experiments and medical diagnosis [1,2]. Studying the amount, types, morphological shape, and configuration of the cells in microscopic images has significant biological and clinical significance in e.g. cancer diagnosis and cancer treatment [3–7]. (Source: Computerized Medical Imaging and Graphics)
Source: Computerized Medical Imaging and Graphics - July 15, 2014 Category: Radiology Authors: Yan Xu, Weiying Wu, Eric I-Chao Chang, Danny Chen, Jian Mu, Peter P. Lee, Kim R.M. Blenman, Zhuowen Tu Source Type: research

Quality assessment of 3D-CTVR, MPR and section plane techniques in ossicular chain reconstruction in middle ear cholesteatoma
It is widely recognized that the ossicular chain plays an important role in sound conduction. In pre-operative cholesteatoma surgery, understanding the extent of abnormality of the ossicles are essential in the reconstruction of the ossicular chain. The two axial and coronal section planes of conventional HRCT (high resolution CT) are insufficient to allow otologists to clearly determine the degree of ossicle conditions such as the absence or destruction of ossicular chain within the surrounding soft tissues. (Source: Computerized Medical Imaging and Graphics)
Source: Computerized Medical Imaging and Graphics - July 14, 2014 Category: Radiology Authors: Yang Liu, Jianjun Sun, Yong Guo, Qiaohui Lu, Danheng Zhao, Yongsheng Lin Source Type: research