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A man with HIV and papules and nodules on the knees
A 39-YEAR-OLD MAN WITH with human immunodeficiency virus (HIV) infection and a CD4 cell count of 528 × 106/L... (Source: Cleveland Clinic Journal of Medicine)
Source: Cleveland Clinic Journal of Medicine - August 31, 2016 Category: Journals (General) Tags: CCJM The Clinical Picture CCJM Emergency Medicine CCJM Dermatology CCJM Infectious Diseases Source Type: research

Diet in the pathophysiology and management of irritable bowel syndrome
DIET PLAYS AN IMPORTANT ROLE in the pathophysiology of irritable bowel syndrome (IBS) and is an effective tool in managing this disorder. This includes a diet low in fermentable oligosaccharides,... (Source: Cleveland Clinic Journal of Medicine)
Source: Cleveland Clinic Journal of Medicine - August 31, 2016 Category: Journals (General) Tags: CCJM Editorial CCJM Viewpoints & Opinions CCJM Gastroenterology and Hepatology Source Type: research

Your patient has chronic leukemia: Now what?
THE ADVENT of targeted therapies has dramatically changed the management of chronic leukemia. Chemotherapy—highly toxic, nonspecific drugs that can be dangerous to patients and providers and result... (Source: Cleveland Clinic Journal of Medicine)
Source: Cleveland Clinic Journal of Medicine - July 27, 2016 Category: Journals (General) Tags: CCJM CME CCJM Medical Grand Rounds CCJM Slide-Out CCJM Drug Therapy CCJM Hematology CCJM Oncology Source Type: research

Is a serum TSH measurement sufficient to monitor the treatment of primary hypothyroidism?
A 28-YEAR-OLD WOMAN returns for follow-up of her hypothyroidism. She was diagnosed 4 years ago when she presented with fatigue, “foggy” thinking, poor concentration, cold intolerance, and... (Source: Cleveland Clinic Journal of Medicine)
Source: Cleveland Clinic Journal of Medicine - July 27, 2016 Category: Journals (General) Tags: CCJM Smart Testing CCJM Diabetes Endocrinology & Metabolism CCJM Drug Therapy Source Type: research

Should patients with stable ischemic heart disease undergo revascularization?
The answer is less clear for these patients than for patients with acute coronary syndromes. In the latter group, percutaneous or surgical revascularization reduces the rates of morbidity and... (Source: Cleveland Clinic Journal of Medicine)
Source: Cleveland Clinic Journal of Medicine - July 27, 2016 Category: Journals (General) Tags: CCJM 1-Minute Consult CCJM Cardiology CCJM Vascular Medicine CCJM Home Page Slider Source Type: research

Thrombotic thrombocytopenic purpura: The role of ADAMTS13
A BREAKTHROUGH in understanding the pathogenesis of thrombotic thrombocytopenic purpura (TTP) came with the discovery of ADAMTS13 (an abbreviation for “a disintegrin and metalloproteinase with... (Source: Cleveland Clinic Journal of Medicine)
Source: Cleveland Clinic Journal of Medicine - July 27, 2016 Category: Journals (General) Tags: CCJM CME CCJM Review CCJM Slide-Out CCJM Hematology CCJM Nephrology CCJM Neurology CCJM Vascular Medicine CCJM Women's Health Source Type: research

Anemia of chronic kidney disease: Treat it, but not too aggressively
ANEMIA IS A FREQUENT complication of chronic kidney disease, occurring in over 90% of patients receiving renal replacement therapy. It is associated with significant morbidity and mortality. While... (Source: Cleveland Clinic Journal of Medicine)
Source: Cleveland Clinic Journal of Medicine - July 27, 2016 Category: Journals (General) Tags: CCJM CME CCJM Review CCJM Slide-Out CCJM Drug Therapy CCJM Hematology CCJM Nephrology CCJM Home Page Slider Source Type: research

Information management for clinicians
ACCESSING, ABSORBING, ORGANIZING, storing, and retrieving potentially useful medical information is a challenge. Physicians used to try meet this challenge with personal libraries of journal articles... (Source: Cleveland Clinic Journal of Medicine)
Source: Cleveland Clinic Journal of Medicine - July 27, 2016 Category: Journals (General) Tags: CCJM Review CCJM Practice Management Source Type: research

Trust the thyroid thermostat
Primary hypothyroidism is common. Most patients... (Source: Cleveland Clinic Journal of Medicine)
Source: Cleveland Clinic Journal of Medicine - July 27, 2016 Category: Journals (General) Tags: CCJM From the Editor CCJM Viewpoints & Opinions CCJM Diabetes Endocrinology Metabolism CCJM Allergy Immunology Source Type: research

Advanced-stage calciphylaxis: Think before you punch
A 53-YEAR-OLD WOMAN presented with extensive, nonulcerated, painful plaques on both calves. She had long-standing diabetes mellitus and had recently started hemodialysis. She had no fever or trauma... (Source: Cleveland Clinic Journal of Medicine)
Source: Cleveland Clinic Journal of Medicine - July 27, 2016 Category: Journals (General) Tags: CCJM The Clinical Picture CCJM Dermatology CCJM Nephrology CCJM Home Page Slider Source Type: research

Geographic tongue
A PREVIOUSLY HEALTHY 35-year-old woman presented with reddish discoloration of her tongue for the past 7 days, accompanied by mild soreness over the area when eating spicy foods. The lesion had also... (Source: Cleveland Clinic Journal of Medicine)
Source: Cleveland Clinic Journal of Medicine - July 27, 2016 Category: Journals (General) Tags: CCJM The Clinical Picture CCJM Dermatology CCJM Rheumatology Source Type: research

Renal failure in HCV cirrhosis
A 54-YEAR-OLD MAN with a history of cirrhosis secondary to hepatitis C virus (HCV) infection has had a progressive decline in kidney function. He was diagnosed with hepatitis C 15 years ago; he tried... (Source: Cleveland Clinic Journal of Medicine)
Source: Cleveland Clinic Journal of Medicine - July 27, 2016 Category: Journals (General) Tags: CCJM Internal Medicine Board Review CCJM Hepatology CCJM Infectious Diseases CCJM Nephrology CCJM Home Page Slider Source Type: research

Premature ventricular contractions: Reassure or refer?
DOCTOR, MY HEART ______.” Fill in the blank with: skips, flip-flops, hiccups, stops, beats in my throat or chest, or any of the various ways patients describe palpitations. One cannot practice... (Source: Cleveland Clinic Journal of Medicine)
Source: Cleveland Clinic Journal of Medicine - July 1, 2016 Category: Journals (General) Tags: CCJM Review CCJM CME CCJM Slide-Out CCJM Cardiology CCJM Home Page Slider Source Type: research

Are we causing anemia by ordering unnecessary blood tests?
A 68-YEAR-OLD WOMAN is admitted for community-acquired pneumonia. She receives antibiotics, and her condition begins to improve after 2 days. She has her blood drawn daily throughout her admission.... (Source: Cleveland Clinic Journal of Medicine)
Source: Cleveland Clinic Journal of Medicine - July 1, 2016 Category: Journals (General) Tags: CCJM Smart Testing CCJM Geriatrics CCJM Hospital Medicine CCJM Hematology CCJM Home Page Slider Source Type: research

Ovarian hyperstimulation syndrome as a complication of molar pregnancy
AN 18-YEAR-OLD WOMAN, pregnant for the third time, presented to the emergency department with constant vaginal bleeding and intermittent cramping for the past 3 weeks. Her last menstrual period was... (Source: Cleveland Clinic Journal of Medicine)
Source: Cleveland Clinic Journal of Medicine - July 1, 2016 Category: Journals (General) Tags: CCJM The Clinical Picture CCJM Diabetes Endocrinology & Metabolism CCJM Imaging CCJM Women's Health CCJM Home Page Slider Source Type: research