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When patients on target-specific oral anticoagulants need surgery
The target-specific oral anticoagulants (TSOACs), eg, dabigatran, rivaroxaban, and apixaban, are changing the way we manage thromboembolic disease. At the same time, many clinicians wonder how best to manage TSOAC therapy when patients need surgery. An in-depth understanding of these drugs is essential to minimize the risk of bleeding and thrombosis perioperatively. (Source: Cleveland Clinic Journal of Medicine)
Source: Cleveland Clinic Journal of Medicine - October 1, 2014 Category: Journals (General) Authors: ANDERSON, M., HASSELL, K. L., TRUJILLO, T. C., WOLFE, B. Tags: Review Source Type: research

Diabetes therapy and cancer risk: Where do we stand when treating patients?
This article discusses the links between diabetes and cancer, the different agents available for treating diabetes, and the cancer risk associated with these therapies. (Source: Cleveland Clinic Journal of Medicine)
Source: Cleveland Clinic Journal of Medicine - October 1, 2014 Category: Journals (General) Authors: CHING SUN, G. E., KASHYAP, S. R., NASR, C. Tags: Review Source Type: research

Managing snoring: When to consider surgery
Snoring can range in significance from merely annoying the patient’s bed partner to being a symptom of obstructive sleep apnea, a risk factor for heart disease and stroke. If conservative measures do not help, primary care physicians can refer patients for consideration of a variety of surgical procedures to keep the airway open during sleep. (Source: Cleveland Clinic Journal of Medicine)
Source: Cleveland Clinic Journal of Medicine - October 1, 2014 Category: Journals (General) Authors: TIEN, D. A., KOMINSKY, A. Tags: Review Source Type: research

Keeping up with immunizations for adults
This paper discusses recommendations from the US Centers for Disease Control and Prevention’s Advisory Committee on Immunization Practices for vaccinating adults against influenza, tetanus, measles, mumps, rubella, varicella, hepatitis A and B, human papillomavirus, shingles (zoster), pneumonia, and meningitis. (Source: Cleveland Clinic Journal of Medicine)
Source: Cleveland Clinic Journal of Medicine - October 1, 2014 Category: Journals (General) Authors: NIELSEN, C. Tags: Medical Grand Rounds Source Type: research

Bench-to-bedside challenges in developing immune protection against breast cancer
This article explains the vaccine strategy, how we think the vaccine will work, and how we plan to move forward through clinical trials. (Source: Cleveland Clinic Journal of Medicine)
Source: Cleveland Clinic Journal of Medicine - October 1, 2014 Category: Journals (General) Authors: TUOHY, V. K. Tags: Medical Grand Rounds Source Type: research

Terry nails in a patient with chronic alcoholic liver disease
(Source: Cleveland Clinic Journal of Medicine)
Source: Cleveland Clinic Journal of Medicine - October 1, 2014 Category: Journals (General) Authors: KHICHAR, S., CHOUDHARY, S. Tags: The Clinical Picture Source Type: research

Should all patients have a resting 12-lead ECG before elective noncardiac surgery?
(Source: Cleveland Clinic Journal of Medicine)
Source: Cleveland Clinic Journal of Medicine - October 1, 2014 Category: Journals (General) Authors: SHARMA, P., DHUNGEL, S., PRABHAKARAN, A. Tags: 1-Minute Consult Source Type: research

In reply
(Source: Cleveland Clinic Journal of Medicine)
Source: Cleveland Clinic Journal of Medicine - October 1, 2014 Category: Journals (General) Authors: SIMON, J. F., SAKHUJA, A., Hyland, J. Tags: Letters to the Editor Source Type: research

Why is metformin contraindicated in chronic kidney disease? (MAY 2014)
(Source: Cleveland Clinic Journal of Medicine)
Source: Cleveland Clinic Journal of Medicine - October 1, 2014 Category: Journals (General) Authors: IMAM, T. H. Tags: Letters to the Editor Source Type: research

To dream the maybe possible dream: A breast cancer vaccine
(Source: Cleveland Clinic Journal of Medicine)
Source: Cleveland Clinic Journal of Medicine - October 1, 2014 Category: Journals (General) Authors: MANDELL, B. F. Tags: From The Editor Source Type: research

In reply
(Source: Cleveland Clinic Journal of Medicine)
Source: Cleveland Clinic Journal of Medicine - September 2, 2014 Category: Journals (General) Authors: SMITH, C. D., ALGUIRE, P. C. Tags: Letters to the Editor Source Type: research

Stress testing (JULY 2014)
(Source: Cleveland Clinic Journal of Medicine)
Source: Cleveland Clinic Journal of Medicine - September 2, 2014 Category: Journals (General) Authors: HOMLER, H. Tags: Letters to the Editor Source Type: research

Radon and lung cancer: Assessing and mitigating the risk
Radon is a naturally occurring radioactive gas. Its progenies emit alpha particles capable of causing tissue damage. Radon exposure is estimated to be the second most common cause of lung cancer in the United States. Management of patients with a history of radon exposure should involve a lung cancer specialist. (Source: Cleveland Clinic Journal of Medicine)
Source: Cleveland Clinic Journal of Medicine - September 2, 2014 Category: Journals (General) Authors: CHOI, H., MAZZONE, P. Tags: Review Source Type: research

The protein-sparing modified fast for obese patients with type 2 diabetes: What to expect
This article reviews the principles of the PSMF and its potential benefits in terms of weight loss, glycemic control, insulin resistance, cardiovascular risk factors, and related complications for patients with type 2 diabetes. (Source: Cleveland Clinic Journal of Medicine)
Source: Cleveland Clinic Journal of Medicine - September 2, 2014 Category: Journals (General) Authors: CHANG, J., KASHYAP, S. R. Tags: Review Source Type: research

Advances in autosomal dominant polycystic kidney disease--2014 and beyond
Autosomal dominant polycystic kidney disease (ADPKD), which frequently leads to end-stage renal disease, currently has no specific drug therapies. Better understanding of its pathogenesis and recent clinical trials have led to more accurate diagnosis of the disease and its manifestations, as well as to promising new approaches to treatment. (Source: Cleveland Clinic Journal of Medicine)
Source: Cleveland Clinic Journal of Medicine - September 2, 2014 Category: Journals (General) Authors: BRAUN, W. E. Tags: Medical Grand Rounds Source Type: research