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PCSK9 inhibition: A promise fulfilled?
Statin therapy has been shown to substantially reduce adverse events associated with low-density-lipoprotein cholesterol (LDL-C) and cardiovascular disease (CVD). Statins alone are often not adequate... (Source: Cleveland Clinic Journal of Medicine)
Source: Cleveland Clinic Journal of Medicine - November 2, 2016 Category: Journals (General) Tags: CCJM Supplement Articles CCJM Supplements CCJM Cardiology CCJM Drug Therapy CCJM Preventive Medicine CCJM Vascular Medicine Source Type: research

Fibromuscular dysplasia: Advances in understanding and management
Fibromuscular dysplasia (FMD) is an uncommon vascular disease that leads to narrowing (with either a beaded appearance or, less commonly, focal stenosis), dissection, or aneurysm of medium-sized... (Source: Cleveland Clinic Journal of Medicine)
Source: Cleveland Clinic Journal of Medicine - November 2, 2016 Category: Journals (General) Tags: CCJM Supplement Articles CCJM Supplements CCJM Cardiology CCJM Imaging CCJM Nephrology CCJM Neurology CCJM Vascular Medicine CCJM Women's Health Source Type: research

Benefits and challenges of caring for international patients
It is much more important to know what sort of a patient has a disease than what sort of a disease a patient has. —Attributed to Sir William Osler1 RECENT YEARS<span... (Source: Cleveland Clinic Journal of Medicine)
Source: Cleveland Clinic Journal of Medicine - October 31, 2016 Category: Journals (General) Tags: CCJM Review CCJM General Internal Medicine CCJM Hospital Medicine CCJM Practice Management Source Type: research

Serotonin syndrome: Preventing, recognizing, and treating it
WITH A SUBSTANTIAL INCREASE in antidepressant use in the United States over the last 2 decades, serotonin syndrome has become an increasingly common and significant clinical concern. In 1999, 6.5% of... (Source: Cleveland Clinic Journal of Medicine)
Source: Cleveland Clinic Journal of Medicine - October 31, 2016 Category: Journals (General) Tags: CCJM Review CCJM Drug Therapy CCJM Emergency Medicine CCJM Mental Health CCJM Neurology Source Type: research

Update on the management of intestinal failure
INTESTINAL FAILURE, THE INABILITY of the gut to maintain nutritional homeostasis,1 is a complication of vascular thrombosis, inflammatory bowel disease, radiation enteritis, obstruction,... (Source: Cleveland Clinic Journal of Medicine)
Source: Cleveland Clinic Journal of Medicine - October 31, 2016 Category: Journals (General) Tags: CCJM CME CCJM Review CCJM Slide-Out CCJM Gastroenterology and Hepatology CCJM Obesity & Weight Management Source Type: research

Influenza: Still more important than Zika virus
THE MASS MEDIA and the medical literature have been saturated in the last few years by concerns about a variety of emerging viral epidemics such as Ebola and Zika. We must always remember that... (Source: Cleveland Clinic Journal of Medicine)
Source: Cleveland Clinic Journal of Medicine - October 31, 2016 Category: Journals (General) Tags: CCJM CME CCJM Review CCJM Home Page Slider CCJM Geriatrics CCJM Infectious Diseases CCJM Women's Health CCJM Slide-Out Source Type: research

Bilateral earlobe creases and coronary artery disease
A 70-YEAR-OLD MAN with hypertension and hypercholesterolemia presented to the emergency department after the acute onset of substernal, pressure-like chest pain while climbing a flight of stairs. His... (Source: Cleveland Clinic Journal of Medicine)
Source: Cleveland Clinic Journal of Medicine - October 31, 2016 Category: Journals (General) Tags: CCJM The Clinical Picture CCJM Cardiology CCJM Emergency Medicine Source Type: research

Seeking medical care abroad: A challenge to empathy
ON AN OTHERWISE PLEASANT evening during the first week of July 2016, a businessman who was a citizen of the United Arab Emirates visiting Cleveland for medical treatment was falsely accused of links... (Source: Cleveland Clinic Journal of Medicine)
Source: Cleveland Clinic Journal of Medicine - October 31, 2016 Category: Journals (General) Tags: CCJM Editorial CCJM Viewpoints & Opinions CCJM General Internal Medicine CCJM Hospital Medicine CCJM Practice Management Source Type: research

The peacock and the doctor
Of the seven deadly sins, the worst is said to be... (Source: Cleveland Clinic Journal of Medicine)
Source: Cleveland Clinic Journal of Medicine - October 31, 2016 Category: Journals (General) Tags: CCJM From the Editor CCJM Viewpoints & Opinions CCJM General Internal Medicine CCJM Hospital Medicine CCJM Practice Management Source Type: research

Plexiform neurofibroma
A 19-YEAR-OLD WOMAN presented with diffuse swelling on her neck and face that had been growing gradually over the past 12 years. There was no family history of similar swelling. <table... (Source: Cleveland Clinic Journal of Medicine)
Source: Cleveland Clinic Journal of Medicine - October 31, 2016 Category: Journals (General) Tags: CCJM The Clinical Picture CCJM Adolescent Medicine CCJM Dermatology CCJM Genetics CCJM Neurology CCJM Oncology CCJM Home Page Slider Source Type: research

Left ventricular thrombosis can still complicate acute myocardial infarction
A 62-YEAR-OLD MAN with hypertension, type 2 diabetes mellitus, and hypercholesterolemia presented to the emergency department with substernal chest pain that started about 15 hours earlier while he... (Source: Cleveland Clinic Journal of Medicine)
Source: Cleveland Clinic Journal of Medicine - October 31, 2016 Category: Journals (General) Tags: CCJM Internal Medicine Board Review CCJM Cardiology CCJM Drug Therapy CCJM Imaging CCJM Vascular Medicine CCJM Home Page Slider Source Type: research

Breaking the pain contract: A better controlled-substance agreement for patients on chronic opioid therapy
REGULATORY BODIES and professional societies have encouraged or mandated written pain treatment agreements for over a decade as a way to establish informed consent, improve adherence, and mitigate... (Source: Cleveland Clinic Journal of Medicine)
Source: Cleveland Clinic Journal of Medicine - October 31, 2016 Category: Journals (General) Tags: CCJM CME CCJM Review CCJM Slide-Out CCJM Drug Therapy CCJM Hospice & Palliative Medicine CCJM Mental Health CCJM Pain CCJM Practice Management Source Type: research

Update in perioperative cardiac medicine
PERIOPERATIVE MEDICINE is an evolving field with a rapidly growing body of literature. Because physicians and patients are often concerned about cardiac risk, we focus this review on perioperative... (Source: Cleveland Clinic Journal of Medicine)
Source: Cleveland Clinic Journal of Medicine - October 3, 2016 Category: Journals (General) Tags: CCJM CME CCJM Review CCJM Slide-Out CCJM Cardiology CCJM Hospital Medicine CCJM Home Page Slider Source Type: research

Evolution of heart failure management: Miles to go
The woods are lovely, dark and deep, But I have promises to keep, And miles to go before I sleep, And miles to go before I sleep. —Robert Frost, “Stopping by Woods on a... (Source: Cleveland Clinic Journal of Medicine)
Source: Cleveland Clinic Journal of Medicine - October 3, 2016 Category: Journals (General) Tags: CCJM Editorial CCJM Viewpoints & Opinions CCJM Cardiology CCJM Critical Care CCJM Drug Therapy CCJM Hospice Palliative Medicine CCJM Hospital Medicine Source Type: research

Air leakage in multiple compartments after endoscopy
A 68-YEAR-OLD MAN with metastatic periampullary adenocarcinoma presented to his usual clinic for a scheduled biliary stent exchange by endoscopic retrograde cholangiopancreatography (ERCP). The stent... (Source: Cleveland Clinic Journal of Medicine)
Source: Cleveland Clinic Journal of Medicine - October 3, 2016 Category: Journals (General) Tags: CCJM The Clinical Picture CCJM Gastroenterology and Hepatology CCJM Imaging CCJM Oncology Source Type: research