An 18-year-old woman with hepatic cysts
(Source: Cleveland Clinic Journal of Medicine)
Source: Cleveland Clinic Journal of Medicine - May 1, 2014 Category: Journals (General) Authors: HO, C. H., LIN, J. Tags: The Clinical Picture Source Type: research

Syncope during a pharmacologic nuclear stress test
(Source: Cleveland Clinic Journal of Medicine)
Source: Cleveland Clinic Journal of Medicine - May 1, 2014 Category: Journals (General) Authors: BUITRAGO, I., WOLINSKY, D., ASHER, C. R. Tags: The Clinical Picture Source Type: research

Niacin's effect on cardiovascular risk: Have we finally learned our lesson?
(Source: Cleveland Clinic Journal of Medicine)
Source: Cleveland Clinic Journal of Medicine - May 1, 2014 Category: Journals (General) Authors: NICHOLLS, S. J. Tags: Commentary Source Type: research

The generalist, the specialist, and the patient with chronic kidney disease
(Source: Cleveland Clinic Journal of Medicine)
Source: Cleveland Clinic Journal of Medicine - May 1, 2014 Category: Journals (General) Authors: MANDELL, B. F. Tags: From The Editor Source Type: research

Recognizing, managing medical consequences of eating disorders in primary care
Eating disorders can lead to serious health problems, and as in many other disorders, primary care physicians are on the front line. Problems that can arise from intentional malnutrition and from purging affect multiple organ systems. Treatment challenges include maximizing weight gain while avoiding the refeeding syndrome. (Source: Cleveland Clinic Journal of Medicine)
Source: Cleveland Clinic Journal of Medicine - April 1, 2014 Category: Journals (General) Authors: DICKSTEIN, L. P., FRANCO, K. N., ROME, E. S., AURON, M. Tags: Review Source Type: research

Don't forget non-Alzheimer dementias
Dementia is commonly encountered in the elderly, with prevalence increasing with age. Although Alzheimer disease is the most recognized form of dementia, other types have distinct clinical features and are often overlooked. Proper identification aids patients, caregivers, and physicians in planning and management. (Source: Cleveland Clinic Journal of Medicine)
Source: Cleveland Clinic Journal of Medicine - April 1, 2014 Category: Journals (General) Authors: FACTORA, R. M., TOUSI, B. Tags: Review Source Type: research

Managing acute coronary syndromes: Decades of progress
This article reviews clinical trials that inform current standards of practice regarding reperfusion, aggressive vs conservative initial approaches, and the appropriate use of aspirin, dual antiplatelet therapy, glycoprotein IIb/IIIa antagonists, anticoagulants, and statins. (Source: Cleveland Clinic Journal of Medicine)
Source: Cleveland Clinic Journal of Medicine - April 1, 2014 Category: Journals (General) Authors: LINCOFF, A. M. Tags: Medical Grand Rounds Source Type: research

The METEOR trial: No rush to repair a torn meniscus
It is uncertain whether arthroscopic partial meniscectomy is better than physical therapy in patients who have a symptomatic torn meniscus on top of osteoarthritis of the knee. The Meniscal Repair in Osteoarthritis Research (METEOR) trial concluded that physical therapy is acceptable at first, and that surgery is not routinely needed. In patients assigned to physical therapy who eventually needed surgery, the delay resulting from a trial of conservative management did not impair outcomes at 12 months from the initial presentation. Here, we analyze the background, design, findings, and clinical implications of the METEOR tr...
Source: Cleveland Clinic Journal of Medicine - April 1, 2014 Category: Journals (General) Authors: HWANG, Y. G., KWOH, C. K. Tags: Interpreting Key Trials Source Type: research

The Clinical Picture: An intravenous drug user with persistent dyspnea and lung infiltrates
(Source: Cleveland Clinic Journal of Medicine)
Source: Cleveland Clinic Journal of Medicine - April 1, 2014 Category: Journals (General) Authors: MBUVAH, F., VENUR, V. A., KISTANGARI, G. Tags: The Clinical Picture Source Type: research

Acute and critical limb ischemia: When time is limb
Acute and critical limb ischemia post significant rates of morbidity and death, and need to be promptly recognized and treated to avoid amputation. Perfusion should be thoroughly assessed using multiple methods, and patients should be considered for revascularization (angioplasty or bypass surgery) to restore blood perfusion. Underlying conditions that need to be assessed and treated include cardiovascular disease, diabetes, and infection. (Source: Cleveland Clinic Journal of Medicine)
Source: Cleveland Clinic Journal of Medicine - April 1, 2014 Category: Journals (General) Authors: SHISHEHBOR, M. H. Tags: Medical Grand Rounds Source Type: research

Appreciating the appetite for reflective practice
(Source: Cleveland Clinic Journal of Medicine)
Source: Cleveland Clinic Journal of Medicine - April 1, 2014 Category: Journals (General) Authors: MANDELL, B. F. Tags: From The Editor Source Type: research

Prevention and treatment of influenza in the primary care office
Influenza, a common respiratory infection, is a source of significant rates of illness, death, and loss of productivity. Annual vaccination is safe and effective in preventing disease and in reducing its severity. Yet a majority of eligible US adults do not receive the annual vaccine, at least in part because of misunderstandings about adverse reactions and clinical effectiveness. (Source: Cleveland Clinic Journal of Medicine)
Source: Cleveland Clinic Journal of Medicine - March 3, 2014 Category: Journals (General) Authors: GOLOVYAN, D. M., MOSSAD, S. B. Tags: Review Source Type: research

New hypertension guidelines: One size fits most?
The report of the panel appointed to the eighth Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC 8) is more evidence-based and focused than its predecessors, outlining a management strategy that is simpler and, in some instances, less aggressive. It has both strengths and weaknesses. (Source: Cleveland Clinic Journal of Medicine)
Source: Cleveland Clinic Journal of Medicine - March 3, 2014 Category: Journals (General) Authors: THOMAS, G., SHISHEHBOR, M., BRILL, D., NALLY, J. V. Tags: Review Source Type: research

When are effective medications just too expensive?
(Source: Cleveland Clinic Journal of Medicine)
Source: Cleveland Clinic Journal of Medicine - March 3, 2014 Category: Journals (General) Authors: MEHTA, S. J., ASCH, D. A. Tags: Editorial Source Type: research

Hepatitis C virus: Here comes all-oral treatment
Treatment for chronic hepatitis C virus (HCV) infection is evolving rapidly. The approval in 2013 of two new direct-acting antivirals—sofosbuvir (a polymerase inhibitor) and simeprevir (a second-generation protease inhibitor)—opens the door for an all-oral regimen, potentially avoiding interferon and its harsh side effects. Other direct-acting antivirals are under development. (Source: Cleveland Clinic Journal of Medicine)
Source: Cleveland Clinic Journal of Medicine - March 3, 2014 Category: Journals (General) Authors: DUGUM, M., O'SHEA, R. Tags: Current Drug Therapy Source Type: research