When the VEST Does Not Fit: Representations of Trial Results Deviating From Rigorous Data Interpretation [On My Mind]
(Source: Circulation: Heart Failure)
Source: Circulation: Heart Failure - April 17, 2018 Category: Cardiology Authors: Allen, L. A., Adler, E. D., Bayes-Genis, A., Brisco-Bacik, M. A., Chirinos, J. A., Claggett, B., Cook, J. L., Fang, J. C., Gustafsson, F., Ho, C. Y., Kapur, N. K., Klewer, S. E., Kociol, R. D., Lanfear, D. E., Vardeny, O., Sweitzer, N. K. Tags: Arrhythmias, Catheter Ablation and Implantable Cardioverter-Defibrillator, Sudden Cardiac Death, Heart Failure On My Mind Source Type: research
Ventricular Assist Device Utilization in Heart Transplant Candidates: Nationwide Variability and Impact on Waitlist Outcomes [Emerging Investigators]
Conclusions:
CF-LVAD utilization may lower waitlist mortality at the expense of lower likelihood of HT. Decision to use CF-LVAD and timing of transition should be individualized based on patient-, center-, and region-level risk factors to achieve optimal outcomes. (Source: Circulation: Heart Failure)
Source: Circulation: Heart Failure - April 17, 2018 Category: Cardiology Authors: Truby, L. K., Garan, A. R., Givens, R. C., Takeda, K., Takayama, H., Trinh, P. N., Yuzefpolskaya, M., Farr, M. A., Naka, Y., Colombo, P. C., Topkara, V. K. Tags: Heart Failure, Transplantation Emerging Investigators Source Type: research
Left Ventricular Assist Device Inflow Cannula Angle and Thrombosis Risk [Original Articles]
Conclusions:
Angulation of the inflow cannula >7° from the apical axis (axis connecting mitral valve and ventricular apex) leads to markedly unfavorable hemodynamics as determined by computational fluid dynamics. Computational hemodynamic simulations incorporating Lagrangian and Eulerian metrics are a powerful tool for studying optimization of LVAD implantation strategies, with the long-term potential of improving outcomes. (Source: Circulation: Heart Failure)
Source: Circulation: Heart Failure - April 17, 2018 Category: Cardiology Authors: Chivukula, V. K., Beckman, J. A., Prisco, A. R., Dardas, T., Lin, S., Smith, J. W., Mokadam, N. A., Aliseda, A., Mahr, C. Tags: Cardiomyopathy, Heart Failure, Complications Original Articles Source Type: research
Incidence, Predictors, and Outcomes Associated With Hypotensive Episodes Among Heart Failure Patients Receiving Sacubitril/Valsartan or Enalapril: The PARADIGM-HF Trial (Prospective Comparison of Angiotensin Receptor Neprilysin Inhibitor With Angiotensin-Converting Enzyme Inhibitor to Determine Impact on Global Mortality and Morbidity in Heart Failure) [Original Articles]
Conclusions:
Hypotension was more common with sacubitril/valsartan relative to enalapril in PARADIGM-HF but did not differentially affect permanent discontinuations. Patients with hypotension during run-in derived similar benefit from sacubitril/valsartan compared with enalapril as those who did not experience hypotension. (Source: Circulation: Heart Failure)
Source: Circulation: Heart Failure - April 11, 2018 Category: Cardiology Authors: Vardeny, O., Claggett, B., Kachadourian, J., Pearson, S. M., Desai, A. S., Packer, M., Rouleau, J., Zile, M. R., Swedberg, K., Lefkowitz, M., Shi, V., McMurray, J. J. V., Solomon, S. D. Tags: Clinical Studies, Heart Failure Original Articles Source Type: research
Early Ambulation Among Hospitalized Heart Failure Patients Is Associated With Reduced Length of Stay and 30-Day Readmissions [Original Articles]
Conclusions:
Multivariable-adjusted hospital-level analysis suggests an association between EA and both shorter length of stay and lower 30-day readmissions. Further prospective studies are needed to validate these findings. (Source: Circulation: Heart Failure)
Source: Circulation: Heart Failure - April 11, 2018 Category: Cardiology Authors: Fleming, L. M., Zhao, X., DeVore, A. D., Heidenreich, P. A., Yancy, C. W., Fonarow, G. C., Hernandez, A. F., Kociol, R. D. Tags: Heart Failure, Mortality/Survival, Quality and Outcomes Original Articles Source Type: research
Pulmonary Effective Arterial Elastance as a Measure of Right Ventricular Afterload and Its Prognostic Value in Pulmonary Hypertension Due to Left Heart Disease [Original Articles]
Conclusions:
Pulmonary Ea and pulmonary arterial compliance more consistently predicted mortality than pulmonary vascular resistance or transpulmonary gradient across a spectrum of left heart disease with pulmonary hypertension, including patients with heart failure with preserved ejection fraction, heart failure with reduced ejection fraction, and pulmonary hypertension with a normal pulmonary vascular resistance. (Source: Circulation: Heart Failure)
Source: Circulation: Heart Failure - April 11, 2018 Category: Cardiology Authors: Tampakakis, E., Shah, S. J., Borlaug, B. A., Leary, P. J., Patel, H. H., Miller, W. L., Kelemen, B. W., Houston, B. A., Kolb, T. M., Damico, R., Mathai, S. C., Kasper, E. K., Hassoun, P. M., Kass, D. A., Tedford, R. J. Tags: Hemodynamics, Heart Failure, Pulmonary Hypertension Original Articles Source Type: research
Advanced Dilated Cardiomyopathy in a Patient With Hutterite Limb-Girdle Muscular Dystrophy: Use of a Left Ventricular Assist Device [Images and Case Reports in Heart Failure]
(Source: Circulation: Heart Failure)
Source: Circulation: Heart Failure - April 6, 2018 Category: Cardiology Authors: Miskew Nichols, B., Nikhanj, A., Wang, F., Freed, D. H., Oudit, G. Y. Tags: Cardiomyopathy, Heart Failure, Hypertrophy, Remodeling Images and Case Reports in Heart Failure Source Type: research
Devil in Disguise: Hints and Pitfalls in Diagnosis of Peripartum Cardiomyopathy [Editorial]
(Source: Circulation: Heart Failure)
Source: Circulation: Heart Failure - April 6, 2018 Category: Cardiology Authors: Bauersachs, J., Koenig, T. Tags: Cardiomyopathy, Heart Failure Editorial Source Type: research
Incidence, Risk Factors, and Clinical Characteristics of Peripartum Cardiomyopathy in South Korea [Original Articles]
Conclusions:
The incidence of PPCM was 1 in 1741 deliveries in South Korea. Patients with PPCM were older, were more associated with primiparity and multiple pregnancy, had more pregnancy-related complications, and revealed higher in-hospital mortality than controls. The number of cases diagnosed as PPCM were decreased over time after delivery; however, a large number of patients were still noted through 12 months after delivery. (Source: Circulation: Heart Failure)
Source: Circulation: Heart Failure - April 6, 2018 Category: Cardiology Authors: Lee, S., Cho, G. J., Park, G. U., Kim, L. Y., Lee, T.-S., Kim, D. Y., Choi, S.-W., Youn, J.-C., Han, S. W., Ryu, K.-H., Na, J. O., Choi, C. U., Seo, H. S., Kim, E. J. Tags: Epidemiology, Cardiomyopathy, Heart Failure Original Articles Source Type: research
Causes and Predictors of 30-Day Readmission in Patients With Acute Myocardial Infarction and Cardiogenic Shock [Original Articles]
Conclusions:
In-hospital mortality and 30-day readmission in cardiogenic shock complicating AMI are significantly elevated. Patients are readmitted mainly for noncardiac causes. Identification of high-risk factors may guide interventions to improve outcomes within this population. (Source: Circulation: Heart Failure)
Source: Circulation: Heart Failure - April 4, 2018 Category: Cardiology Authors: Shah, M., Patil, S., Patel, B., Agarwal, M., Davila, C. D., Garg, L., Agrawal, S., Kapur, N. K., Jorde, U. P. Tags: Heart Failure, Complications, Mortality/Survival, Quality and Outcomes, Acute Coronary Syndromes Original Articles Source Type: research
TTR (Transthyretin) Stabilizers Are Associated With Improved Survival in Patients With TTR Cardiac Amyloidosis [Original Articles]
Conclusions:
TTR stabilizers are associated with decreased death and OHT in TTR cardiac amyloidosis. These results need to be confirmed by ongoing randomized clinical trials. (Source: Circulation: Heart Failure)
Source: Circulation: Heart Failure - April 3, 2018 Category: Cardiology Authors: Rosenblum, H., Castano, A., Alvarez, J., Goldsmith, J., Helmke, S., Maurer, M. S. Tags: Cardiomyopathy, Heart Failure Original Articles Source Type: research
Association of Biomarker Clusters With Cardiac Phenotypes and Mortality in Patients With HIV Infection [Original Articles]
Conclusions:
Serum biomarkers can be used to classify HIV-infected individuals into separate clusters for differentiating cardiopulmonary structural and functional abnormalities and can predict mortality independent of these structural and functional measures. (Source: Circulation: Heart Failure)
Source: Circulation: Heart Failure - April 3, 2018 Category: Cardiology Authors: Scherzer, R., Shah, S. J., Secemsky, E., Butler, J., Grunfeld, C., Shlipak, M. G., Hsue, P. Y. Tags: Heart Failure Original Articles Source Type: research
Accelerated Cardiomyocyte Proliferation in the Heart of a Neonate With LEOPARD Syndrome-Associated Fatal Cardiomyopathy [Images and Case Reports in Heart Failure]
(Source: Circulation: Heart Failure)
Source: Circulation: Heart Failure - March 30, 2018 Category: Cardiology Authors: Nakagama, Y., Inuzuka, R., Ichimura, K., Hinata, M., Takehara, H., Takeda, N., Kakiuchi, S., Shiraga, K., Asakai, H., Shindo, T., Hirata, Y., Saitoh, M., Oka, A. Tags: Developmental Biology, Genetics, Cardiomyopathy, Heart Failure, Hypertrophy Images and Case Reports in Heart Failure Source Type: research
Apophenia and the Crafting of a Circulation: Heart Failure Issue [Editor's Perspective]
(Source: Circulation: Heart Failure)
Source: Circulation: Heart Failure - March 16, 2018 Category: Cardiology Authors: Sweitzer, N. K. Tags: Heart Failure Editor ' s Perspective Source Type: research
Same Story, Different Disease: It Is Time to Change the Storyline for Racial Minorities and Patients of Lower Socioeconomic Status [Editorial]
(Source: Circulation: Heart Failure)
Source: Circulation: Heart Failure - March 16, 2018 Category: Cardiology Authors: Breathett, K. Tags: Race and Ethnicity, Transplantation, Health Services, Quality and Outcomes Editorial Source Type: research
