Effect of tadalafil on reduction of necrosis in the ischemic zone in a rat comb burn model
Burns are dynamic wounds in which the extent of injury tends to progress over time due to a combination of ischemia-reperfusion due to decreased perfusion, inflammation and oxidative stress [1 –5]. In his monumental paper in 1953 Jackson described how burns classically affected the skin [6]. The zone directly in contact with the thermal insult underwent immediate and complete necrosis and was termed the zone of necrosis. Immediately surrounding this inner core was a zone of ischemia or stasis in which the microcirculation was diminished, but if improved, was potentially reversible. (Source: Burns : Journal of the Interna...
Source: Burns : Journal of the International Society for Burn Injuries - June 9, 2018 Category: Cosmetic Surgery Authors: Adam J. Singer, Henry Towery, Steve A. McClain Source Type: research

Accurately identifying blast injuries in civilian burn practice
A blast injury is a severe multi-system traumatic injury that may occur in tandem with any burn resulting from an enclosed or high-order explosion. Pathological sequelae can be severe, vary and affect the brain as well as any organs holding air-tissue interfaces such as the eyes, ears and lungs. Consequently traumatic brain injury, blast lung (ARDS), traumatic ocular neuropathy and conversational hearing loss are all well documented complications [1,2]. Following the recent asymmetric conflicts in Iraq and Afghanistan, blast injury has experienced a renaissance in interest. (Source: Burns : Journal of the International Soc...
Source: Burns : Journal of the International Society for Burn Injuries - June 7, 2018 Category: Cosmetic Surgery Authors: Joseph A. Ward, Georgina Phillips, Niall A.J. Martin Tags: Letter to the Editor Source Type: research

The recovery of post-burn hypertrophic scar in a monitored pressure therapy intervention programme and the timing of intervention
Hypertrophic scar (HS) following burn injuries and other types of trauma or surgeries is a common complication and a major challenge to health professionals and patients [1]. In Asian populations, despite a high survival rate of 98.9% after burns [2], the prevalence rate of HS after burn injury is as high as 70%, much higher than that of Caucasian populations [2,3]. Hypertrophic scar is characterized by its red to purple colour, elevated height, decreased pliability, tenderness, pain and itch [4 –7]. (Source: Burns : Journal of the International Society for Burn Injuries)
Source: Burns : Journal of the International Society for Burn Injuries - June 7, 2018 Category: Cosmetic Surgery Authors: Pan Li, Cecilia Wai Ping Li-Tsang, Xue Deng, Xiaoyun Wang, Hanjie Wang, Yuting Zhang, Ziming Tan, Chengqi He Source Type: research

Changes in burn mortality in Bangladesh: Findings from Bangladesh Health and Injury Survey (BHIS) 2003 and 2016
Burn injury is the fourth most prevalent cause of injury in the world [1,2]. Annually about 265,000 burn-related deaths occur worldwide [3]. Owing to the physical, psychological, economic and social impact of burn, it has become an eminent public health concern globally [4]. Thermal, electrical and chemical burns, etc. are well-known mechanisms of burn injuries [5]. Among unintentional injuries, electrocution is becoming a rising concern, especially in low-income countries [6]. The socioeconomic condition, age, gender, residence and comorbid conditions are established risk factors worldwide [7]. (Source: Burns : Journal of...
Source: Burns : Journal of the International Society for Burn Injuries - June 7, 2018 Category: Cosmetic Surgery Authors: Saidur Rahman Mashreky, Riffat Ara Shawon, Animesh Biswas, Junnatul Ferdoush, Afrida Unjum, A.K.M. Fazlur Rahman Source Type: research

The abbreviated burn severity index as a predictor of acute respiratory distress syndrome in young individuals with severe flammable starch-based powder burn
Severe burn injuries require high-cost medical services for serious health issues associated with morbidity, mortality, and rehabilitation [1]. The severity of a burn is mainly related to its total body surface area (TBSA) and the lesion depth. Severe burn injury is also associated with inhalation injury, which is also a risk factor of mortality [2]. Moreover, acute respiratory distress syndrome (ARDS) in patients with critically ill burns commonly leads to mortality [3]. Pneumonia and inflammation are the major causes of ARDS in patients with burns. (Source: Burns : Journal of the International Society for Burn Injuries)
Source: Burns : Journal of the International Society for Burn Injuries - June 6, 2018 Category: Cosmetic Surgery Authors: Kuan-Hsun Lin, Chi-Ming Chu, Yu-Kai Lin, Hao-Yu Chiao, Ta-Wei Pu, Yuan-Ming Tsai, Ying-Yi Chen, Hsu-Kai Huang, Hung Chang, Shih-Chun Lee, Tsai-Wang Huang Source Type: research

Toxic epidermal necrolysis data from the CELESTE multinational registry. Part I: Epidemiology and general microbiological characteristics
Toxic epidermal necrolysis (TEN) is a life-threatening autoimmune disease predominantly manifested in the skin and mucous membranes [1]. It is a toxic allergic reaction to the presence of a foreign antigen, most commonly a medication [2]. The pathophysiological basis of this disease is the induction of massive apoptosis in the area of dermo-epidermal junction by caspase and non-caspase mechanisms [3,4]. (Source: Burns : Journal of the International Society for Burn Injuries)
Source: Burns : Journal of the International Society for Burn Injuries - June 6, 2018 Category: Cosmetic Surgery Authors: B. Lipov ý, J. Holoubek, M. Hanslianová, M. Cvanová, L. Klein, I. Grossová, R. Zajíček, P. Bukovčan, J. Koller, M. Baran, P. Lengyel, L. Eimer, M. Jandová, M. Košťál, P. Brychta, CELESTE Study Group Source Type: research

Attribution bias underlying burns-induced anxiety symptoms
Burn injuries are a debilitating cause of morbidity and mortality. They cause clear cosmetic and functional sequelae, often necessitating physical and aesthetic rehabilitation [1]. Surgery and physiotherapy form the core of burns treatment and can produce rapid, demonstrable improvements to the physical injury [2]. However, despite significant reduction in mortality from advances in specialised wound care and reconstructive surgical techniques, mental health remains a large contributory factor in the long-term quality of life (QoL) [3,4]. (Source: Burns : Journal of the International Society for Burn Injuries)
Source: Burns : Journal of the International Society for Burn Injuries - June 6, 2018 Category: Cosmetic Surgery Authors: Mena Farag, Edward J.R. Watson, Kl ára Nenadlová, Christian Asher, Sayed Al-Aidarous, Sundhiya Mandalia, Lisa M. Williams, Trudi L. Edginton, Declan Collins, Marcela P. Vizcaychipi Source Type: research

Comparison of intralesional verapamil versus intralesional corticosteroids in treatment of keloids and hypertrophic scars: A randomized controlled trial
Hypertrophic scars and keloids are dermal fibro-proliferative disorders which can lead to pruritus, disfigurement and pain. Against hypertrophic scars which are limited to the injury sites and after quick growth can partially regress, keloids extend beyond the extent of the original wound and have a permanent and long evolution [1,2]. (Source: Burns : Journal of the International Society for Burn Injuries)
Source: Burns : Journal of the International Society for Burn Injuries - June 6, 2018 Category: Cosmetic Surgery Authors: Robabeh Abedini, Pardis Sasani, Hamid Reza Mahmoudi, Maryam Nasimi, Amir Teymourpour, Zahra Shadlou Source Type: research

A population-based retrospective cohort study to assess the mental health of patients after a non-intentional burn compared with uninjured people
Burn injury is an important cause of unintentional morbidity and for many it can be a traumatic life experience [1]. Advances over the past decades in the surgical care of burn patients have resulted in improved survival rates. However, many burn survivors face long periods of treatment and recovery, as well as physical [2] and psychosocial issues [3]. Extended hospital stays are often associated with feelings of social isolation, loss of independence, issues related to return to work and financial dependency, and increased stress [4]. (Source: Burns : Journal of the International Society for Burn Injuries)
Source: Burns : Journal of the International Society for Burn Injuries - June 6, 2018 Category: Cosmetic Surgery Authors: Janine M. Duke, Sean M. Randall, James H. Boyd, Fiona M. Wood, Mark W. Fear, Suzanne Rea Source Type: research

Pre-burn malnutrition increases operative mortality in burn patients who undergo early excision and grafting in a sub-Saharan African burn unit: Methodological issues
We read the article by Grudziak et al. with great interest [1]. They aimed to determine the burn injury outcomes following operative intervention based on nutritional status. They concluded that poor nutrition is associated with post-operative mortality in burned patients. Undoubtedly, their results make contribution to the area but some important methodological issues need to be noted. (Source: Burns : Journal of the International Society for Burn Injuries)
Source: Burns : Journal of the International Society for Burn Injuries - June 5, 2018 Category: Cosmetic Surgery Authors: Ahad Ashrafi-Asgarabad, Saeid Safiri Tags: Letter to the Editor Source Type: research

Graft orientation influences meshing ratio
Split thickness skin grafting is a mainstay surgical technique for soft tissue reconstruction worldwide. In cases of large defects or limited donor site availability, the classic example being major burn injuries, skin grafts may be expanded beyond their original geometry. This permits a smaller graft to reconstruct a larger defect. Principally, there are two techniques used for skin expansion: tissue expansion, and skin graft meshing [1,2]. The first technique consists of overstretching the skin by gradual mechanical distention, usually in the form of a surgically inserted underlying silicone implant that is progressively...
Source: Burns : Journal of the International Society for Burn Injuries - May 31, 2018 Category: Cosmetic Surgery Authors: Lukas Capek, Cormac Flynn, Martin Molitor, Simon Chong, Petr Henys Source Type: research

Ultrasound elastography reliably identifies altered mechanical properties of burned soft tissues
The aim of this article is to characterize the material properties of a burned tissue with regard to unburned tissue. This is of importance because burns are the most common injuries in both civilian and combat scenarios [1], and a noninvasive technique that results in the rapid identification of a burned tissue in a reliable manner could be clinically useful. Existing techniques are reviewed in Ref. [1]. Outside of clinical judgment and biopsy, most imaging-based techniques have been developed for such purposes, of which laser Doppler imaging (LDI) remains the only technique that is approved by the US Food and Drug Admini...
Source: Burns : Journal of the International Society for Burn Injuries - May 30, 2018 Category: Cosmetic Surgery Authors: Hanglin Ye, Rahul, Saurabh Dargar, Uwe Kruger, Suvranu De Source Type: research

Hypnosis for burn wound care pain and anxiety: A systematic review and meta-analysis
Most recent data from the World Health Organization indicates nearly 11 million persons worldwide are burned severely enough to require medical attention yearly [1]. In the United States, in 2013, 40000 patients were hospitalized for a burn injury [2]. Severe burns often require surgical interventions such as skin grafts or debridement (removal of dead tissues) in order to heal [3]. Moreover, wounds must be cleaned daily to promote healing and prevent infection, which typically include debridement and dressing changes [4]. (Source: Burns : Journal of the International Society for Burn Injuries)
Source: Burns : Journal of the International Society for Burn Injuries - May 24, 2018 Category: Cosmetic Surgery Authors: Sarah-Claude Proven çal, Suzie Bond, Elie Rizkallah, Ghassan El-Baalbaki Tags: Review Source Type: research

“Home-made slime”: A novel cause for paediatric burns’ referrals; do we need to raise awareness?
Homemade slime has become a phenomenon amongst children recreationally, eight to twelve years old [1], extending into the healthcare profession for paediatric sensory and functional based therapy [2]. There have been several reported cases of chemical burns associated with the home-made compound [3]. At the Children ’s burns centre in Manchester, UK, we have recently seen three, referred to us as chemical burns, but on further investigation, an alternative aetiology to these cases is suggested. (Source: Burns : Journal of the International Society for Burn Injuries)
Source: Burns : Journal of the International Society for Burn Injuries - May 24, 2018 Category: Cosmetic Surgery Authors: Christian Asher, Razli Dalan, Mohamed Ismail Aly Tags: Letter to the Editor Source Type: research

From traditional biochemical signals to molecular markers for detection of sepsis after burn injuries
Following a severe burn injury, the body must respond immediately to activate the immune system in order to challenge the insult and to restore homeostasis while also preventing any bacteria from establishing an infection [1]. However, burns can leave skin and other tissues vulnerable to bacterial infection and increase the risk of sepsis (Fig. 1A). Sepsis is defined as life-threatening organ dysfunction [2 –4] caused by a dysregulated host response to infection [5]. This process is regarded as a major public-health concern, with the mortality rate, depending on the severity of the insult, ranging from 30 to 50% [6]. (So...
Source: Burns : Journal of the International Society for Burn Injuries - May 22, 2018 Category: Cosmetic Surgery Authors: Balam Mu ñoz, Rocío Suárez-Sánchez, Oscar Hernández-Hernández, Rafael Franco-Cendejas, Hernán Cortés, Jonathan J. Magaña Tags: Review Source Type: research