Adherence to drug treatments and adjuvant barrier repair therapies are key factors for clinical improvement in mild to moderate acne: the ACTUO observational prospective multicenter cohort trial in 643 patients
In acne, several studies report a poor adherence to treatments. We evaluate, in a real-life setting conditions, the impact of compliance to physician’s instructions, recommendations and adherence to the treatm... (Source: BMC Dermatology)
Source: BMC Dermatology - September 11, 2015 Category: Dermatology Authors: Raúl de Lucas, Gerardo Moreno-Arias, Montserrat Perez-López, Ángel Vera-Casaño, Sonia Aladren and Massimo Milani Source Type: research

Adherence to drug treatments and adjuvant barrier repair therapies are key factors for clinical improvement in mild to moderate acne: the ACTUO observational prospective multicenter cohort trial in 643 patients
Conclusions: Good adherence to medication plus adherence to adjuvants was significantly associated with a higher clinical improvement unlike those that despite adherence with medication had a low adherence to adjuvants. A good adherence to adjuvant treatment was associated with improved adherence and better treatment outcomes in mild to moderate acne patients. (ISRCTN Registry: ISRCTN14257026). (Source: BMC Dermatology)
Source: BMC Dermatology - September 11, 2015 Category: Dermatology Authors: Raúl de LucasGerardo Moreno-AriasMontserrat Perez-LópezÁngel Vera-CasañoSonia AladrenMassimo Milanion behalf of ACTUO Investigators study group Source Type: research

Skin diseases in pediatric patients attending a tertiary dermatology hospital in Northern Tanzania: a cross-sectional study
Skin diseases affect 21–87 % of children in developing countries in Africa. However, the spectrum of the skin diseases varies from region to region due to several factors such as genetics, socioeconomic and en... (Source: BMC Dermatology)
Source: BMC Dermatology - September 10, 2015 Category: Dermatology Authors: Samson K. Kiprono, Julia W. Muchunu and John E. Masenga Source Type: research

Skin diseases in pediatric patients attending a tertiary dermatology hospital in Northern Tanzania: a cross-sectional study
Conclusions: Skin infections are still the main cause of dermatological consultations in children although with a reduced prevalence. Inflammatory skin conditions are increasing and can be attributed to improved socioeconomic status and HIV pandemic. (Source: BMC Dermatology)
Source: BMC Dermatology - September 10, 2015 Category: Dermatology Authors: Samson KipronoJulia MuchunuJohn Masenga Source Type: research

Magnitude and associated factors of Atopic dermatitis among children in Ayder referral hospital, Mekelle, Ethiopia
Atopic Dermatitis (AD) is now a day’s increasing in prevalence globally. A Prevalence of 5–25 % have been reported in different country. Even if its prevalence is known in most countries especially in developi... (Source: BMC Dermatology)
Source: BMC Dermatology - August 25, 2015 Category: Dermatology Authors: Abraham Getachew Kelbore, Workalemahu Alemu, Ashenafi Shumye and Sefonias Getachew Source Type: research

Magnitude and associated factors of Atopic dermatitis among children in Ayder referral hospital, Mekelle, Ethiopia
Background: Atopic Dermatitis (AD) is now a day’s increasing in prevalence globally. A Prevalence of 5–25 % have been reported in different country. Even if its prevalence is known in most countries especially in developing countries there is scarcity with regard to prevalence and associated risk factors of AD among children in Ethiopia settings. The aim of this study was to determine the magnitude and associated factors of atopic dermatitis among children in Ayder referral hospital, Mekelle, Ethiopia. Methods: A facility-based cross-sectional study design was conducted among 477 children aged from 3 months to 14 ye...
Source: BMC Dermatology - August 25, 2015 Category: Dermatology Authors: Abraham KelboreWorkalemahu AlemuAshenafi ShumyeSefonias Getachew Source Type: research

Role models in a preventive program for hand eczema among healthcare workers: a qualitative exploration of their main tasks and associated barriers and facilitators
Conclusions: Most role models performed only the tasks they learned during their training. They mentioned a wide range of barriers and facilitators for the performing of their role. To enhance the functioning of the role models, a suggestion would be to select role models by taking into account prior coaching experience.Trial registrationTrial registration number: NTR2812 (Source: BMC Dermatology)
Source: BMC Dermatology - August 20, 2015 Category: Dermatology Authors: Anne BruinewoudEsther van der MeerJoost van der GuldenJohannes AnemaCécile Boot Source Type: research

Perinatal probiotic supplementation in the prevention of allergy related disease: 6 year follow up of a randomised controlled trial
Conclusions: Maternal probiotic ingestion alone may be sufficient for long term reduction in the cumulative incidence of AD, but not other allergy related diseases.Trial registrationClinicalTrials.gov identifier: NCT00159523 (Source: BMC Dermatology)
Source: BMC Dermatology - August 1, 2015 Category: Dermatology Authors: Melanie SimpsonChristian DotterudOla StorrøRoar JohnsenTorbjørn Øien Source Type: research

Small lymphocytic lymphoma with florid perniosis-like features: a case report
Conclusions: This unusual cutaneous manifestation of a lymphoma and the favourable response to systemic therapy may be instructive for the management of other patients who develop similar perniosis-like features. (Source: BMC Dermatology)
Source: BMC Dermatology - July 23, 2015 Category: Dermatology Authors: Taylor MorrisRosetta MazzolaBrian BerryDouglas SawyerDavid Saltman Source Type: research

Features of human scabies in resource-limited settings: the Cameroon case
Conclusion: Human scabies remains preponderant in our milieu. Populations should be educated on preventive measures in order to avoid this disease, and clinicians’ knowledges must be strengthened for its proper diagnosis and management. (Source: BMC Dermatology)
Source: BMC Dermatology - July 23, 2015 Category: Dermatology Authors: Emmanuel KouotouJobert NansseuIsidore SieleunouDefo DefoAnne-Cécile BissekElie Ndam Source Type: research

Effect of etanercept therapy on psoriasis symptoms in patients from Latin America, Central Europe, and Asia: a subset analysis of the PRISTINE trial
Background: Psoriasis prevalence and characteristics in Asia, Central Europe, and Latin America have not been thoroughly investigated and there are no large trials for biologic treatments for patients from these regions. The goal of this analysis was to report clinical response to anti-tumor necrosis factor-alpha treatment in these patients. Methods: Patients from Argentina, Czech Republic, Hungary, Mexico, Taiwan, and Thailand (N = 171) were included in this subset analysis of the PRISTINE trial. Patients with stable moderate-to-severe plaque psoriasis were blinded and randomized to receive etanercept 50 mg once week...
Source: BMC Dermatology - May 21, 2015 Category: Dermatology Authors: L. KemenyM. AmayaP. CetkovskaN. RajatanavinW-R. LeeA. SzumskiL. MarshallE. MahgoubE. Aldinç Source Type: research

Effects of tofacitinib on lymphocyte sub-populations, CMV and EBV viral load in patients with plaque psoriasis
Conclusions: Twelve weeks of treatment with tofacitinib had no clinically significant effects on CMV or EBV viral load, suggesting that lymphocyte sub-populations critical to the response to chronic viral infections and viral reactivation were not significantly affected. Replication of these findings during long-term use of tofacitinib will allow confirmation of this observation. (Source: BMC Dermatology)
Source: BMC Dermatology - May 8, 2015 Category: Dermatology Authors: Fernando ValenzuelaKim PappDavid PariserStephen TyringRobert WolkMarjorie BuonannoJeff WangHuaming TanHernan Valdez Source Type: research

Subjective stress reactivity in psoriasis – a cross sectional study of associated psychological traits
Conclusion: According to our results, patients who perceive stress as a causal factor in their psoriasis might have a more vulnerable psychological constitution. This finding suggests important opportunities for clinicians to identify patients who may benefit from additional psychological exploration and support. (Source: BMC Dermatology)
Source: BMC Dermatology - May 2, 2015 Category: Dermatology Authors: Charlotta RemrödKarin SjöströmÅke Svensson Source Type: research

BMC Dermatology reviewer acknowledgement, 2014
Contributing reviewerThe editors of BMC Dermatology would like to thank all our reviewers who have contributed their time to the journal in Volume 14 (2014). (Source: BMC Dermatology)
Source: BMC Dermatology - March 18, 2015 Category: Dermatology Authors: Guangde Tu Source Type: research

Validation of the global resource of eczema trials (GREAT database)
Conclusions: The sensitivity of the GREAT database for trials from 2000 onwards was high (75/88 trials, 94%). Sensitivity for the period prior to 2000 was less sensitive, due to differences in how the trials were identified prior to this time.‘Dual’ filtering for new records has recently become part of the GREAT database methodology and should further improve the sensitivity of the database in time. The GREAT database can be considered as a primary source for future systematic reviews including randomised controlled trials of eczema treatments, but searches should be supplemented by checking reference lists for eligibl...
Source: BMC Dermatology - March 14, 2015 Category: Dermatology Authors: Helen NankervisAlison DevineHywel WilliamsJohn IngramElizabeth DoneyFinola DelamereSherie SmithKim Thomas Source Type: research