Human T cell lymphotropic virus type 1- associated infective dermatitis in KwaZulu Natal, South Africa
Conclusions: IDH is a distinct entity which also affects South Africans. Our patients were older at presentation and the majority did not present with nasal crusting as has been described in other countries. (Source: BMC Dermatology)
Source: BMC Dermatology - October 23, 2013 Category: Dermatology Authors: Carol HlelaNatalie GrahamAhmed BhigjeeGraham TaylorNonhlanhla KhumaloAnisa Mosam Source Type: research

Toll-Like receptor 2 activation and comedogenesis: implications for the pathogenesis of acne
Conclusions: TLR activation and secretion of IL-1alpha from keratinocytes may be initiating steps in comedogenesis and, therefore, critical to the pathophysiology of acne. (Source: BMC Dermatology)
Source: BMC Dermatology - September 6, 2013 Category: Dermatology Authors: Joanne SelwayTomasz KurczabTerence KealeyKenneth Langlands Source Type: research

Treatment and referral patterns for psoriasis in United Kingdom primary care: a retrospective cohort study
Conclusions: Estimates of the incidence of diagnosed adult psoriasis, referral rates to dermatologists, and characteristics of referred patients may assist in understanding the burden on the UK healthcare system and managing this population in primary and secondary care. (Source: BMC Dermatology)
Source: BMC Dermatology - August 19, 2013 Category: Dermatology Authors: Javaria KhalidGary GlobeKathleen FoxDina ChauAndrew MaguireChio-Fang Chiou Source Type: research

Metabolic changes in psoriatic skin under topical corticosteroid treatment
Conclusion: This MR method demonstrates that metabolism in psoriatic skin becomes similar to that of uninvolved skin after effective corticosteroid treatment. MR profiling of skin lesions reflect metabolic alterations related to pathogenesis and treatment effects. (Source: BMC Dermatology)
Source: BMC Dermatology - August 14, 2013 Category: Dermatology Authors: Beathe SitterMargareta JohnssonJostein HalgunsetTone Bathen Source Type: research

Improved emollient use reduces atopic eczema symptoms and is cost neutral in infants: before-and-after evaluation of a multifaceted educational support programme
Conclusion A community-based multifaceted educational support programme greatly increased emollient use, reducing symptoms of atopic eczema and general practitioner contacts, without increasing cost. Significant benefits may accrue to the families and carers of children with atopic eczema due to improved sleep patterns and greater feeling of control. PEST, a new simple measure of acute and remitting atopic eczema severity designed to help parents and children to monitor and manage eczema, merits further evaluation. (Source: BMC Dermatology)
Source: BMC Dermatology - May 16, 2013 Category: Dermatology Authors: James MasonJulie CarrCarolyn BuckleySteve HewittPhillip BerryJosh TaylorMichael Cork Source Type: research

Exposure to indoor tanning in France: a population based study
Conclusions: This first study on artificial UV radiation exposure in France has better quantified and characterized the users. It has also defined the state of knowledge and the perception of risk by the general French population. This work will contribute to determine actions of prevention to reduce cancer risk related to artificial UV radiation. (Source: BMC Dermatology)
Source: BMC Dermatology - April 23, 2013 Category: Dermatology Authors: Tarik BenmarhniaChristophe LéonFrançois Beck Source Type: research

BMC Dermatology reviewer acknowledgement, 2012
Contributing reviewersThe editors of BMC Dermatology would like to thank all our reviewers who have contributed to the journal in Volume 12 (2012). (Source: BMC Dermatology)
Source: BMC Dermatology - April 15, 2013 Category: Dermatology Authors: Hayley Henderson Source Type: research

BMC Dermatology reviewer acknowledgement, 2012
The editors of BMC Dermatology would like to thank all our reviewers who have contributed to the journal in Volume 12 (2012). (Source: BMC Dermatology)
Source: BMC Dermatology - April 15, 2013 Category: Dermatology Authors: Hayley Henderson Source Type: research

Single application of 4% dimeticone liquid gel versus two applications of 1% permethrin creme rinse for treatment of head louse infestation: a randomised controlled trial
This study was designed to confirm this in comparison with two applications of 1% permethrin. Methods: We have performed a single centre parallel group, randomised, controlled, open label, community based trial, with domiciliary visits, in Cambridgeshire, UK. Treatments were allocated through sealed instructions derived from a computer generated list. We enrolled 90 children and adults with confirmed head louse infestation analysed by intention to treat (80 per-protocol after 4 drop outs and 6 non-compliant). The comparison was between 4% dimeticone liquid gel applied once for 15 minutes and 1% permethrin creme rinse appli...
Source: BMC Dermatology - April 1, 2013 Category: Dermatology Authors: Ian BurgessElizabeth BruntonNazma Burgess Source Type: research

Barriers and facilitators of adherence to medical advice on skin self-examination during melanoma follow-up care
DiscussionThe identification of short and long-term predictors of skin self-examination and an increased understanding of barriers will allow health care professionals to better address patient difficulties in adhering to this life-saving health behavior. Furthermore, the findings will enable the development and evaluation of evidence-based, comprehensive intervention strategies. Ultimately, these findings could impact a wide range of outreach programs and secondary prevention initiatives for other populations with increased melanoma risk. (Source: BMC Dermatology)
Source: BMC Dermatology - March 1, 2013 Category: Dermatology Authors: Annett KörnerMartin DrapeauBrett ThombsZeev RosbergerBeatrice WangManish KhannaAlan SpatzAdina CoroiuRosalind GarlandGerald Batist Source Type: research

TGFß signaling regulates lipogenesis in human sebaceous glands cells
Conclusion: TGFβ signaling plays an essential role in sebaceous gland regulation by maintaining sebocytes in an undifferentiated state. This data was generated using a novel method for human sebocyte culture, which is likely to prove generally useful in investigations of sebaceous gland growth and differentiation. These findings open a new paradigm in human skin biology with important implications for skin therapies. (Source: BMC Dermatology)
Source: BMC Dermatology - January 23, 2013 Category: Dermatology Authors: Adrian McNairnYanne DoucetJulien DemaudeMarion BrusadelliChristopher GordonArmando Uribe-RiveraPaul LambertCharbel BouezLionel BretonGéraldine Guasch Source Type: research

TGFbeta signaling regulates lipogenesis in human sebaceous glands cells
Conclusion: TGFbeta signaling plays an essential role in sebaceous gland regulation by maintaining sebocytes in an undifferentiated state. This data was generated using a novel method for human sebocyte culture, which is likely to prove generally useful in investigations of sebaceous gland growth and differentiation. These findings open a new paradigm in human skin biology with important implications for skin therapies. (Source: BMC Dermatology)
Source: BMC Dermatology - January 23, 2013 Category: Dermatology Authors: Adrian McNairnYanne DoucetJulien DemaudeMarion BrusadelliChristopher GordonArmando Uribe-RiveraPaul LambertCharbel BouezLionel BretonGéraldine Guasch Source Type: research

Calciphylaxis ¿ a challenging & solvable task for plastic surgery? A case report
Conclusion: It can be suggested that this agonizing disease needs indeed a multidisciplinary approach involving Nephrologists, Dermatologists, Intensive Care Physicians and Plastic Surgeons, taking into consideration that surgical correction can achieve further improvement in a specialized centre. Notwithstanding, further cohort studies should be approached clinically to insight the light on this disease with special regard to the prognosis after this approach. (Source: BMC Dermatology)
Source: BMC Dermatology - January 14, 2013 Category: Dermatology Authors: Savas TsolakidisGerrit GriebAndrzej PiatkowskiZiyad AlharbiErhan DemirDavid SimonsNorbert Pallua Source Type: research

Calciphylaxis -- a challenging & solvable task for plastic surgery? A case report
Conclusion: It can be suggested that this agonizing disease needs indeed a multidisciplinary approach involving Nephrologists, Dermatologists, Intensive Care Physicians and Plastic Surgeons, taking into consideration that surgical correction can achieve further improvement in a specialized centre. Notwithstanding, further cohort studies should be approached clinically to insight the light on this disease with special regard to the prognosis after this approach. (Source: BMC Dermatology)
Source: BMC Dermatology - January 14, 2013 Category: Dermatology Authors: Savas TsolakidisGerrit GriebAndrzej PiatkowskiZiyad AlharbiErhan DemirDavid SimonsNorbert Pallua Source Type: research

Sentinel lymph node biopsy in melanoma: Our 8-year clinical experience in a single French institute (2002¿2009)
Conclusion: Our data confirm previous studies and support the clinical usefulness of SLNB as a reliable and accurate staging method in patients with cutaneous melanoma. However, the benefit of additional CLND in patients with positive SLN remains to be demonstrated. (Source: BMC Dermatology)
Source: BMC Dermatology - December 10, 2012 Category: Dermatology Authors: Caroline Biver-DalleEve PuzenatMarc PuyraveauDelphine DelroeuxHatem BoulahdourFrances SheppardFabien PelletierPhilippe HumbertFrançois Aubin Source Type: research