BMC Dermatology reviewer acknowledgement 2014
Contributing reviewersThe editors of BMC Dermatology would like to thank all our reviewers who have contributed to the journal in Volume 14 (2014). (Source: BMC Dermatology)
Source: BMC Dermatology - February 27, 2015 Category: Dermatology Authors: Hayley Henderson Source Type: research
Exploring the association between Morgellons disease and Lyme disease: identification of Borrelia burgdorferi in Morgellons disease patients
Conclusions:
Our study using multiple detection methods confirms that MD is a true somatic illness associated with Borrelia spirochetes that cause Lyme disease. Further studies are needed to determine the optimal treatment for this spirochete-associated dermopathy. (Source: BMC Dermatology)
Source: BMC Dermatology - February 12, 2015 Category: Dermatology Authors: Marianne MiddelveenCheryl BandoskiJennie BurkeEva SapiKatherine FilushYean WangAgustin FrancoPeter MayneRaphael Stricker Source Type: research
Digital photography in skin cancer screening by mobile units in remote areas of Brazil
Conclusions:
Given the high sensitivity and PPV, Teledermatology seems to be a suitable tool for skin cancer screening by MPU in remote areas of Brazil. (Source: BMC Dermatology)
Source: BMC Dermatology - December 24, 2014 Category: Dermatology Authors: Carlos SilveiraThiago SilvaJosé FregnaniRené da Costa VieiraRaphael HaikelKari SyrjänenAndré CarvalhoEdmundo Mauad Source Type: research
Innate lymphoid cells and the skin
Innate lymphoid cells are an emerging family of effector cells that contribute to lymphoid organogenesis, metabolism, tissue remodelling and protection against infections. They maintain homeostatic immunity at barrier surfaces such as lung, skin and gut (Nature 464:1367-1371, 2010, Nat Rev Immunol 13: 145-149, 2013). Several human and mouse studies suggest a role for innate lymphoid cells in inflammatory skin conditions including atopic eczema and psoriasis. Here we review the innate lymphoid cell family and discuss their function in the skin and during inflammation. (Source: BMC Dermatology)
Source: BMC Dermatology - November 26, 2014 Category: Dermatology Authors: Maryam SalimiGraham Ogg Source Type: research
Association of variation in the LAMA3 gene, encoding the alpha-chain of laminin 5, with atopic dermatitis in a German case-control cohort
Background:
Atopic dermatitis (AD) is a chronic inflammatory skin disorder caused by complex interaction of genetic and environmental factors. Besides mutations in the filaggrin gene, leading to impaired skin barrier function, variation in genes encoding additional skin proteins has been suggested to contribute to disease risk. Laminin 5, playing an important role in skin integrity, is composed of three subunits encoded by the LAMA3, LAMB3 and LAMC2 genes in which biallelic mutations cause epidermolysis bullosa junctionalis. We aimed at evaluating the role of variation in the LAMA3, LAMB3 and LAMC2 genes for AD pathogenesi...
Source: BMC Dermatology - November 3, 2014 Category: Dermatology Authors: Susanne StemmlerQumar ParwezElisabeth Petrasch-ParwezJoerg EpplenSabine Hoffjan Source Type: research
Testing the effectiveness of a self-efficacy based exercise intervention for adults with venous leg ulcers: protocol of a randomised controlled trial
This study seeks to address a significant gap in current wound management practice by providing evidence for the effectiveness of a home-based exercise program for adults with venous leg ulcers. Theory-driven, evidence-based strategies that can improve an individual's exercise self-efficacy and self-management capacity could have a significant impact in improving the management of people with venous leg ulcers. Information gained from this study will provide much needed information on management of this chronic disease to promote health and independence in this population.Trial registration: Australian New Zealand Clinical...
Source: BMC Dermatology - October 3, 2014 Category: Dermatology Authors: Jane O¿BrienKathleen FinlaysonGraham KerrHelen Edwards Source Type: research
Tomotherapy concomitant with cetuximab, followed by cetuximab as single-agent therapy for unresectable squamous cell carcinoma of the skin: a case report
Conclusion:
The treatment was effective and feasible. Considering these excellent results, further studies about concomitant tomotherapy with Cetuximab for advanced/inoperable SCC of the skin are needed. (Source: BMC Dermatology)
Source: BMC Dermatology - September 30, 2014 Category: Dermatology Authors: Sara FaliveneFrancesca GiuglianoAntonio GrimaldiRossella Di FrancoDiego ToledoMatteo MutoFabrizio CammarotaValentina BorzilloPaolo AsciertoPaolo Muto Source Type: research
Employment is maintained and sick days decreased in psoriasis/psoriatic arthritis patients with etanercept treatment
Background:
Psoriasis and psoriatic arthritis (PsA) impair quality of life, including reduction in employment or job duties. The PRESTA (Psoriasis Randomized Etanercept STudy in Patients with Psoriatic Arthritis) study, a randomized, double-blind, two-dose trial, examined the efficacy of etanercept treatment in patients with moderate-to-severe plaque psoriasis and PsA and the main results have been presented previously. This analysis examined employment status, job duties and sick days, pre-defined endpoints in PRESTA, among this patient population.
Methods:
Participants (N = 752) were randomized to receive etanercept 50 m...
Source: BMC Dermatology - August 5, 2014 Category: Dermatology Authors: Robert BoggsSarolta KárpátiWenzhi LiTheresa WilliamsRonald PedersenLotus MallbrisRobert Gniadecki Source Type: research
Low rate of dermatology outpatient visits in Asian-Americans: an initial survey study for associated patient-related factors
Conclusions:
Identification of patient-related factors that associate with dermatology clinic visits in Asian-Americans is important so that this potential gap in dermatologic care can be better addressed through future studies. (Source: BMC Dermatology)
Source: BMC Dermatology - August 2, 2014 Category: Dermatology Authors: Bharathi LingalaAshley WysongShufeng LiAllison TruongDavid KimAnne Chang Source Type: research
Two sisters reveal autosomal recessive inheritance of epidermodysplasia verruciformis: a case report
Conclusions:
In this report, the patient's parents did not have epidermodysplasia verruciformis lesions or a consanguineous marriage. EV did not develop in the elder sister until five years of age, so the parents did not perceive EV as an inherited disease. The probability that EV developed in both sisters was only 6.25%. Thus, it is rare for both sisters to develop epidermodysplasia verruciformis lesions considering that the parents were presumed to be carriers and the disease reveal an autosomal recessive pattern of inheritance. (Source: BMC Dermatology)
Source: BMC Dermatology - July 21, 2014 Category: Dermatology Authors: Rui YoshidaToshihiko KatoMasahiko KawaseMariko HondaTsuyoshi Mitsuishi Source Type: research
A systematic literature review of pediculosis due to head lice in the Pacific Island Countries and Territories: what country specific research on head lice is needed?
Conclusions:
Current local evidence on head lice in the PICTs is minimal and totally inadequate to guide any recommendations for treatment or control. We recommend that local research is required to generate evidence on: i) epidemiology; ii) knowledge, attitudes and practices of health care providers and community members; iii) efficacy of local commercially available pharmaceutical treatments and local customary treatments; iv) acceptability, accessibility and affordability of available treatment strategies; and iv) appropriate control strategies for families, groups and institutions. We also recommend that operational re...
Source: BMC Dermatology - June 24, 2014 Category: Dermatology Authors: Rick SpeareHumpress HarringtonDeon CanyonPeter Massey Source Type: research
Survey and online discussion groups to develop a patient-rated outcome measure on acceptability of treatment response in vitiligo
Conclusions:
This study represents the first step in developing a patient reported measure of treatment success in vitiligo trials. Further work is now needed to assess its construct validity and responsiveness to change. (Source: BMC Dermatology)
Source: BMC Dermatology - June 14, 2014 Category: Dermatology Authors: Selina TourKim ThomasDawn-Marie WalkerPaul LeightonAdrian YongJonathan Batchelor Source Type: research
HLA class II alleles may influence susceptibility to adult dermatomyositis and polymyositis in a Han Chinese population
Conclusions:
Our results demonstrate that HLA alleles may be involved in susceptibility to adult DM and PM in the Han Chinese population. (Source: BMC Dermatology)
Source: BMC Dermatology - June 4, 2014 Category: Dermatology Authors: Xiang GaoLei HanLan YuanYongchen YangGuimei GouHengjuan SunLing LuLiming Bao Source Type: research
Dermoscopy as an adjuvant tool for detecting skin leiomyomas in patient with uterine fibroids and cerebral cavernomas
Conclusions:
This observation highlights the usefulness of dermoscopy in the diagnosis of cutaneous leiomyomas disclosing multiple cutaneous and uterine leiomyomatosis syndrome. Dermoscopy should be performed for non-melanocytic multiple lesions mimicking leiomyomas in a large number of patients, to establish a strict classification and identify false negative cases or evaluate them as dermatofibromas. In this case, the dermatologist recognized the risk of renal cancer and cerebral cavernomas. (Source: BMC Dermatology)
Source: BMC Dermatology - April 16, 2014 Category: Dermatology Authors: Laura DiluvioClaudia TortiAlessandro TerrinoniEleonora CandiRaffaella PiancatelliEmilio PiccioneEvelin PaternòSergio ChimentiAugusto OrlandiElena CampioneLuca Bianchi Source Type: research
