TGFß signaling regulates lipogenesis in human sebaceous glands cells

Conclusion:
TGFβ signaling plays an essential role in sebaceous gland regulation by maintaining sebocytes in an undifferentiated state. This data was generated using a novel method for human sebocyte culture, which is likely to prove generally useful in investigations of sebaceous gland growth and differentiation. These findings open a new paradigm in human skin biology with important implications for skin therapies.

Source: BMC Dermatology - January 23, 2013 Category: Dermatology Authors: Adrian McNairnYanne DoucetJulien DemaudeMarion BrusadelliChristopher GordonArmando Uribe-RiveraPaul LambertCharbel BouezLionel BretonGéraldine Guasch Source Type: research