Effects of tofacitinib on lymphocyte sub-populations, CMV and EBV viral load in patients with plaque psoriasis
Conclusions:
Twelve weeks of treatment with tofacitinib had no clinically significant effects on CMV or EBV viral load, suggesting that lymphocyte sub-populations critical to the response to chronic viral infections and viral reactivation were not significantly affected. Replication of these findings during long-term use of tofacitinib will allow confirmation of this observation.
Source: BMC Dermatology - Category: Dermatology Authors: Fernando ValenzuelaKim PappDavid PariserStephen TyringRobert WolkMarjorie BuonannoJeff WangHuaming TanHernan Valdez Source Type: research