Best Practice and Research. Clinical Gastroenterology 
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This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.Tobacco smoking, alcohol consumption and gastro-oesophageal reflux disease
Publication date: October 2017Source: Best Practice & Research Clinical Gastroenterology, Volume 31, Issue 5Author(s): Eivind Ness-Jensen, Jesper LagergrenAbstractGastro-oesophageal reflux disease (GORD) develops when reflux of gastric content causes troublesome symptoms or complications. The main symptoms are heartburn and acid regurgitation and complications include oesophagitis, strictures, Barrett's oesophagus and oesophageal adenocarcinoma. In addition to hereditary influence, GORD is associated with lifestyle factors, mainly obesity. Tobacco smoking is regarded as an aetiological factor of GORD, while alcohol consump...
Source: Best Practice and Research Clinical Gastroenterology - July 10, 2018 Category: Gastroenterology Source Type: research
Aims & Scope/ Editorial Board
Publication date: October 2017Source: Best Practice & Research Clinical Gastroenterology, Volume 31, Issue 5Author(s): (Source: Best Practice and Research Clinical Gastroenterology)
Source: Best Practice and Research Clinical Gastroenterology - July 10, 2018 Category: Gastroenterology Source Type: research
The role of smoking and alcohol behaviour in management of functional gastrointestinal disorders
Publication date: October 2017Source: Best Practice & Research Clinical Gastroenterology, Volume 31, Issue 5Author(s): Bodil OhlssonAbstractFunctional gastrointestinal disorders (FGIDs) are common disorders in the population. Lifestyle habits have been suspected to influence the presence and degree of symptoms, and many studies have examined the role of food components and physical activity on the disease development. The role of smoking and alcohol intake on FGID has been less thoroughly examined. This systematic literature review, of a large amount of studies from different countries around the world with different desig...
Source: Best Practice and Research Clinical Gastroenterology - July 10, 2018 Category: Gastroenterology Source Type: research
Intervening in disease through genetically-modified bacteria
Publication date: December 2017Source: Best Practice & Research Clinical Gastroenterology, Volume 31, Issue 6Author(s): Adilson K. Ferreira, Lisley I. Mambelli, Saravanan Y. PillaiAbstractThe comprehension of the molecular basis of different diseases is rapidly being dissected as a consequence of advancing technology. Consequently, proteins with potential therapeutic usefulness, including cytokines and signaling molecules have been identified in the last decades. However, their clinical use is hampered by disadvantageous functional and economic considerations. One of the most important of these considerations is targeted t...
Source: Best Practice and Research Clinical Gastroenterology - July 10, 2018 Category: Gastroenterology Source Type: research
Preface to “Gut microbiome in health and disease”
Publication date: December 2017Source: Best Practice & Research Clinical Gastroenterology, Volume 31, Issue 6Author(s): Maikel P. Peppelenbosch (Source: Best Practice and Research Clinical Gastroenterology)
Source: Best Practice and Research Clinical Gastroenterology - July 10, 2018 Category: Gastroenterology Source Type: research
The gastrointestinal microbiota and its role in oncogenesis
Publication date: December 2017Source: Best Practice & Research Clinical Gastroenterology, Volume 31, Issue 6Author(s): S.Y. Lam, J. Yu, S.H. Wong, M.P. Peppelenbosch, G.M. FuhlerAbstractAdvances in research techniques have made it possible to map the microbial communities in the gastrointestinal (GI) tract, where the majority of bacteria in the human body reside. Disturbances in these communities are referred to as dysbiosis and have been associated with GI cancers. Although dysbiosis is observed in several GI malignancies, the specific role of these changes has not been understood to the extent of Helicobacter pylori (HP...
Source: Best Practice and Research Clinical Gastroenterology - July 10, 2018 Category: Gastroenterology Source Type: research
Microbiome measurement: Possibilities and pitfalls
Publication date: December 2017Source: Best Practice & Research Clinical Gastroenterology, Volume 31, Issue 6Author(s): Djawad Radjabzadeh, André G. Uitterlinden, Robert KraaijAbstractMicrobiome research is an emerging field in medical sciences. Several studies have made headways in understanding the influence of microbes on our health and disease states. Further progress in mapping microbiome populations across different body sites and understanding the underlying mechanisms of microbiome-host interactions depends critically on study design, collection protocols, analytical genetic techniques, and reference databases. In...
Source: Best Practice and Research Clinical Gastroenterology - July 10, 2018 Category: Gastroenterology Source Type: research
Lifestyle alters GUT-bacteria function: Linking immune response and host
Publication date: December 2017Source: Best Practice & Research Clinical Gastroenterology, Volume 31, Issue 6Author(s): Omid Jazayeri, S. Mojtaba Daghighi, Farhad RezaeeAbstractMicrobiota in human is a “mixture society” of different species (i.e. bacteria, viruses, funguses) populations with a different way of relationship classification to Human. Human GUT serves as the host of the majority of different bacterial populations (GUT flora, more than 500 species), which are with us (“from the beginning”) in an innate manner known as the commensal (no harm to each other) and symbiotic (mutual benefit) relationship. A h...
Source: Best Practice and Research Clinical Gastroenterology - July 10, 2018 Category: Gastroenterology Source Type: research
Action and function of Akkermansia muciniphila in microbiome ecology, health and disease
Publication date: December 2017Source: Best Practice & Research Clinical Gastroenterology, Volume 31, Issue 6Author(s): Noora Ottman, Sharon Y. Geerlings, Steven Aalvink, Willem M. de Vos, Clara BelzerAbstractThe discovery of Akkermansia muciniphila has opened new avenues for the use of this abundant intestinal symbiont in next generation therapeutic products, as well as targeting microbiota dynamics. A. muciniphila is known to colonize the mucosal layer of the human intestine where it triggers both host metabolic and immune responses. A. muciniphila is particularly effective in increasing mucus thickness and increasing ...
Source: Best Practice and Research Clinical Gastroenterology - July 10, 2018 Category: Gastroenterology Source Type: research
Action and function of Faecalibacterium prausnitzii in health and disease
Publication date: December 2017Source: Best Practice & Research Clinical Gastroenterology, Volume 31, Issue 6Author(s): Carmen Veríssima Ferreira-Halder, Alessandra Valéria de Sousa Faria, Sheila Siqueira AndradeAbstractFaecalibacterium prausnitzii, anaerobic bacteria, is one of the main components of gut microbiota and the most important butyrate-producing bacteria in the human colon. So far, this commensal bacterium has been considered as a bioindicator of human health, once when its population is altered (decreased), inflammatory processes are favored. Several reports in the literature highlighted that the amount of F...
Source: Best Practice and Research Clinical Gastroenterology - July 10, 2018 Category: Gastroenterology Source Type: research
Action and function of Chromobacterium violaceum in health and disease: Violacein as a promising metabolite to counteract gastroenterological diseases
Publication date: December 2017Source: Best Practice & Research Clinical Gastroenterology, Volume 31, Issue 6Author(s): Giselle Zenker Justo, Nelson DuránAbstractChromobacterium violaceum is a Gram negative, β-proteobacterium found in the microbiota of tropical and subtropical environments. Although considered an opportunistic pathogen, infection rapidly progress to fatal sepsis, with metastatic abscesses. It is noteworthy the multidrug resistant phenotype of C. violaceum and the possibility of relapse. Recently, an influence of global climate in the incidence of cases beyond the previous areas has been observed. Furthe...
Source: Best Practice and Research Clinical Gastroenterology - July 10, 2018 Category: Gastroenterology Source Type: research
NAFLD, Helicobacter species and the intestinal microbiome
Publication date: December 2017Source: Best Practice & Research Clinical Gastroenterology, Volume 31, Issue 6Author(s): Natalia Castaño-Rodríguez, Hazel M. Mitchell, Nadeem O. KaakoushAbstractNon-alcoholic fatty liver disease (NAFLD) has become the most common chronic liver disease worldwide. It is well-accepted that gut dysbiosis is associated with NAFLD, however, there is some conflicting evidence regarding the nature of these alterations. Infection with Helicobacter species, mainly H. pylori, has also been associated with increased NAFLD risk, however, some studies have failed to reproduce this finding. Further studi...
Source: Best Practice and Research Clinical Gastroenterology - July 10, 2018 Category: Gastroenterology Source Type: research
Intestinal microbiome and permeability in patients with autoimmune hepatitis
Publication date: December 2017Source: Best Practice & Research Clinical Gastroenterology, Volume 31, Issue 6Author(s): Wangfeng Cai, Ying Ran, Yanni Li, Bangmao Wang, Lu ZhouAbstractAutoimmune hepatitis (AIH) is a severe inflammatory liver disease. The underlying mechanisms remain unclear, but recent studies provided new perspectives on altered intestinal microbiome and permeability in AIH animal models and patients, highlighting gut-liver crosstalk in the pathogenesis of AIH. Transgenic AIH mice carrying HLA-DR3 showed reduced diversity and total load of gut microbiota. Germ-free mice are resistant to concanavalin A-indu...
Source: Best Practice and Research Clinical Gastroenterology - July 10, 2018 Category: Gastroenterology Source Type: research
Microbiome, pattern recognition receptor function in health and inflammation
Publication date: December 2017Source: Best Practice & Research Clinical Gastroenterology, Volume 31, Issue 6Author(s): David Fawkner-Corbett, Alison Simmons, Kaushal ParikhAbstractThe innate immune system plays an important role in shaping the microbiota into configurations that are tolerated and beneficial to the host, thereby playing a crucial role in human health. Innate immunity is based on the fundamental principle that Pattern Recognition Receptors (PRRs) recognise pathogen associated molecular patterns as non-self-entities and trigger intracellular signalling pathways that lead to the induction of numerous cytokine...
Source: Best Practice and Research Clinical Gastroenterology - July 10, 2018 Category: Gastroenterology Source Type: research
Diet, microbiome, and colorectal cancer
Publication date: December 2017Source: Best Practice & Research Clinical Gastroenterology, Volume 31, Issue 6Author(s): Sergey R. KonstantinovAbstractThe scientific interests in the colorectal cancer (CRC) associated microbiome have increased significantly in the past decade. Mechanistically, several members of the human microbiome and products thereof have been implicated as inductors of the pathogenic inflammation related to CRC. Conversely, the activities of the human intestinal microbial community influenced by specific diet might confer a protective effect against the CRC risks and progression. As the microbiome is bo...
Source: Best Practice and Research Clinical Gastroenterology - July 10, 2018 Category: Gastroenterology Source Type: research
